Zobrazeno 1 - 10
of 316
pro vyhledávání: '"Karam El-Bayoumy"'
Autor:
Kun-Ming Chen, Yuan-Wan Sun, Jiafen Hu, Karla Balogh, Krishne Gowda, Cesar Aliaga, Dongxiao Sun, Neil Christensen, Shantu Amin, Karam El-Bayoumy
Publikováno v:
ACS Omega, Vol 9, Iss 7, Pp 8434-8438 (2024)
Externí odkaz:
https://doaj.org/article/18061059da3b466ba1a6dc2a7e724b02
Autor:
Sarah A. Brendle, Jingwei J. Li, Vonn Walter, Todd D. Schell, Michael Kozak, Karla K. Balogh, Song Lu, Neil D. Christensen, Yusheng Zhu, Karam El-Bayoumy, Jiafen Hu
Publikováno v:
Pathogens, Vol 12, Iss 12, p 1452 (2023)
Human papillomavirus (HPV)-induced oropharyngeal cancer now exceeds HPV-induced cervical cancer, with a noticeable sex bias. Although it is well established that women have a more proficient immune system, it remains unclear whether immune control of
Externí odkaz:
https://doaj.org/article/149d7cf9818e413ba9c00c4e24f6679d
Autor:
Andrea Manni, Yuan-Wan Sun, Todd D. Schell, Tymofiy Lutsiv, Henry Thompson, Kun-Ming Chen, Cesar Aliaga, Junjia Zhu, Karam El-Bayoumy
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1422 (2023)
Immunotherapy targeting program cell death protein 1 (PD-1) in addition to chemotherapy has improved the survival of triple-negative breast cancer (TNBC) patients. However, the development of resistance and toxicity remain significant problems. Using
Externí odkaz:
https://doaj.org/article/54762d617f8a4219972a7e469044795b
Autor:
Kun-Ming Chen, Henry Thompson, John P. Vanden-Heuvel, Yuan-Wan Sun, Neil Trushin, Cesar Aliaga, Krishne Gowda, Shantu Amin, Bruce Stanley, Andrea Manni, Karam El-Bayoumy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Docosahexaenoic acid (DHA) is known to inhibit breast cancer in the rat. Here we investigated whether DHA itself or select metabolites can account for its antitumor action. We focused on metabolites derived from the lipoxygenase (LOX) pathwa
Externí odkaz:
https://doaj.org/article/c4bb46a811624f08af671d39c0e3ef81
Autor:
Ana H. Sales, Marina Kolbanovskiy, Nicholas E. Geacintov, Kun-Ming Chen, Yuan-Wan Sun, Karam El-Bayoumy
Publikováno v:
Antioxidants, Vol 11, Iss 11, p 2110 (2022)
As demonstrated by us earlier and by other researchers, a diet containing freeze-dried black raspberries (BRB) inhibits DNA damage and carcinogenesis in animal models. We tested the hypothesis that the inhibition of DNA damage by BRB is due, in part,
Externí odkaz:
https://doaj.org/article/6affea84318e48c6a9ff316d2ca9194b
Autor:
Douglas B. Stairs, Mary E. Landmesser, Cesar Aliaga, Kun-Ming Chen, Yuan-Wan Sun, Karam El-Bayoumy
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
One of the major risk factors for head and neck squamous cell carcinoma (HNSCC) is tobacco smoke exposure, but the mechanisms that can account for disease development remain to be fully defined. Utilizing our HNSCC mouse model, we analyzed oral squam
Externí odkaz:
https://doaj.org/article/d9871f36b4b740b192e267be62d94a4f
Publikováno v:
Chemical research in toxicology. 35(10)
Nitro group containing xenobiotics include drugs, cancer chemotherapeutic agents, carcinogens (e.g., nitroarenes and aristolochic acid) and explosives. The nitro group undergoes a six-electron reduction to form sequentially the nitroso
Publikováno v:
Chemical Research in Toxicology. 35:2296-2309
1-Nitropyrene (1-NP) and 1,8-dinitropyrene (1,8-DNP) are diesel exhaust constituents and are classified by the International Agency for Research on Cancer as probable (Group 2A) or possible (Group 2B) human carcinogens. These nitroarenes undergo meta
Publikováno v:
Chemical Research in Toxicology. 35:2152-2159
Autor:
Kun-Ming Chen, Yuan-Wan Sun, Nicolle M Krebs, Dongxiao Sun, Jacek Krzeminski, Lisa Reinhart, Krishne Gowda, Shantu Amin, Susan Mallery, John P Richie, Karam El-Bayoumy
Publikováno v:
Carcinogenesis
Polycyclic aromatic hydrocarbons (PAHs) are recognized as potential etiological agents in the development of oral cancer in smokers. In particular, benzo[a]pyrene (B[a]P) and dibenzo[def,p]chrysene (DB[a,l]P) are detected in cigarette smoke and the e