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pro vyhledávání: '"Karakike, E."'
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Akademický článek
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Acute respiratory distress syndrome (ARDS) in COVID-19 has been associated with catastrophic inflammation. We present measurements in humans and a new animal model implicating a role in danger-associated molecular patterns. Calprotectin (S100A8/A9) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::2a9cc25dd83d9e36833055a99c39e617
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3219967
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3219967
The pandemic 2019 novel coronavirus disease (COVID-19) shares certain clinical characteristics with other acute viral infections. We studied the whole-blood transcriptomic host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::02aab4bb6351ae083f08b572e87f6017
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056305
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3056305
Background It was studied if early suPAR-guided anakinra treatment can prevent severe respiratory failure (SRF) of COVID-19. Methods 130 patients with suPAR ≥6 ng/ml were assigned to subcutaneous anakinra 100mg once daily for 10 days. Primary outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::7413aa627084b09fd3d3170b07c20071
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2997204
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2997204
Lipopolysaccharide (LPS) and monophosphoryl lipid A (MPLA) induce, overall, similar transcriptional profiles in healthy individuals, although LPS has been shown to more potently induce pro-inflammatory cytokines. We explore herein whether MPLA could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::65694831079008290fd71025fae60c9e
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2999888
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2999888
Hydrogen sulfide (H2S) has recently been recognized as a novel gaseous transmitter with several anti-inflammatory properties. The role of host- derived H2S in infections by Pseudomonas aeruginosa was investigated in clinical and mouse models. H2S con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::4074d8a701bea80423f800074f98b6a0
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2999937
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2999937
Background: Anakinra might improve the prognosis of patients with moderate to severe COVID-19 (ie, patients requiring oxygen supplementation but not yet receiving organ support). We aimed to assess the effect of anakinra treatment on mortality in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::a9acb0a5c15e9c11554aca5f19ae9e2c
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2999762
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:2999762
The beneficial effect of sinus bradycardia during targeted temperature management (TTM) in cardiac arrest patients remains doubtful. We aimed to investigate the impact of sinus bradycardia on survival and neurological outcome. MEDLINE (PubMed), Cochr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::0a7a0c017d63475495af55327dd5b9ef
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3121333
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3121333
Autor:
Karakike, E. Kyriazopoulou, E. Tsangaris, I. Routsi, C. Vincent, J.-L. Giamarellos-Bourboulis, E.J.
Background: Since the Sepsis-3 criteria, change in Sequential Organ Failure Assessment (SOFA) score has become a key component of sepsis identification. Thus, it could be argued that reversal of this change (ΔSOFA) may reflect sepsis response and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::ec96c491da30a7752299237878c981ad
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3105439
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3105439