Phenotyping EMT and MET cellular states in lung cancer patient liquid biopsies at a personalized level using mass cytometry.

Autor: Karacosta LG; Department of Biomedical Data Science, Stanford University, Stanford, CA, 94305, USA.; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 77054, USA., Pancirer D; Stanford Cancer Institute - Clinical Trials Office, Stanford University, Stanford, CA, 94305, USA., Preiss JS; Stanford Cancer Institute - Clinical Trials Office, Stanford University, Stanford, CA, 94305, USA., Benson JA; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, 94305, USA., Trope W; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, 94305, USA., Shrager JB; Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, 94305, USA.; Palo Alto VA Health Care System, Palo Alto, USA., Sung AW; Division of Pulmonary, Allergy & Critical Care Medicine, Department of Medicine, Stanford University, Stanford, CA, 94305, USA., Neal JW; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA, 94305, USA., Bendall SC; Department of Pathology, Stanford University, Stanford, CA, 94305, USA., Wakelee H; Division of Oncology, Department of Medicine, Stanford University, Stanford, CA, 94305, USA., Plevritis SK; Department of Biomedical Data Science, Stanford University, Stanford, CA, 94305, USA. sylvia.plevritis@stanford.edu.; Department of Radiology, Stanford University, Stanford, CA, 94305, USA. sylvia.plevritis@stanford.edu.

Publikováno v: Scientific reports [Sci Rep] 2023 Dec 08; Vol. 13 (1), pp. 21781. Date of Electronic Publication: 2023 Dec 08.

Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation.

Autor: Adler FR; Department of Mathematics, University of Utah, Salt Lake City, UT 84112, USA; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA., Anderson ARA; Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA., Bhushan A; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA., Bogdan P; Ming Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA., Bravo-Cordero JJ; Division of Hematology and Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Brock A; Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA., Chen Y; Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA., Cukierman E; Cancer Signaling and Microenvironment Program, Marvin and Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA 19111, USA; Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA., DelGiorno KE; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA., Denis GV; Boston University-Boston Medical Center Cancer Center, Boston University School of Medicine, Boston, MA 02118, USA., Ferrall-Fairbanks MC; J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA; University of Florida Health Cancer Center, University of Florida, Gainesville, FL 32611, USA., Gartner ZJ; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA; NSF Center for Cellular Construction, San Francisco, CA 94158, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA., Germain RN; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Gordon DM; Department of Biology, Stanford University, Stanford, CA 94305, USA., Hunter G; Department of Biology, Clarkson University, Potsdam, NY 13699, USA., Jolly MK; Centre for BioSystems Science and Engineering, Indian Institute of Science, Bangalore, 560012, India., Karacosta LG; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Mythreye K; Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL 35294, USA., Katira P; Mechanical Engineering Department, San Diego State University, San Diego, CA 92182, USA; Computational Sciences Research Center, San Diego State University, San Diego, CA 92182, USA., Kulkarni RP; Department of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA; Department Biomedical Engineering, Oregon Health and Science University, Portland, OR 97239, USA; Department Oncological Sciences, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA; Cancer Early Detection Advanced Research Center (CEDAR), Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA; Operative Care Division, VA Portland Health Care System, Portland, OR 97239, USA., Kutys ML; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA., Lander AD; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; Center for Complex Biological Systems, University of California, Irvine, Irvine, CA 92697, USA., Laughney AM; Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10021, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA., Levine H; Center for Theoretical Biological Physics, Northeastern University, Boston, MA 02115, USA., Lou E; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Lowenstein PR; Department of Neurosurgery, Rogel Cancer Center, The University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Rogel Cancer Center, The University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI 48109, USA., Masters KS; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA., Pe'er D; Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Peyton SR; Department of Chemical Engineering, University of Massachusetts, Amherst, MA 01003, USA., Platt MO; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, Atlanta, GA 30322, USA; Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Emory University, Atlanta, GA 30322, USA., Purvis JE; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Quon G; Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616, USA., Richer JK; Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; University of Colorado Cancer Center, Aurora, CO 80045, USA., Riddle NC; Department of Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA., Rodriguez A; Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Snyder JC; Department of Surgery, Duke University, Durham, NC 27710, USA; Department of Cell Biology, Duke University, Durham, NC 27710, USA., Lee Szeto G; Allen Institute for Immunology, Seattle, WA 98109, USA; Seagen, Bothell, WA 98021, USA., Tomlin CJ; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA 94720, USA., Yanai I; Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA; Institute for Computational Medicine, NYU Langone Health, New York, NY 10016, USA., Zervantonakis IK; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15232, USA; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15232, USA., Dueck H; Division of Cancer Biology, National Cancer Institute, National Institutes of Health, Rockville, MD 20850, USA. Electronic address: hannah.dueck@nih.gov.

Publikováno v: Cell systems [Cell Syst] 2023 Apr 19; Vol. 14 (4), pp. 252-257.

Multiomics Analysis of Spatially Distinct Stromal Cells Reveals Tumor-Induced O-Glycosylation of the CDK4-pRB Axis in Fibroblasts at the Invasive Tumor Edge.

Autor: Bouchard G; Department of Biomedical Data Science, Stanford University, Stanford, California.; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California.; Department of Radiation Oncology, Stanford University, Stanford, California., Garcia-Marques FJ; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California., Karacosta LG; Department of Biomedical Data Science, Stanford University, Stanford, California., Zhang W; Department of Biomedical Data Science, Stanford University, Stanford, California., Bermudez A; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California., Riley NM; Departments of Chemistry, Stanford University, Stanford, California., Varma S; Department of Pathology, Stanford University, Stanford, California., Mehl LC; Department of Biomedical Data Science, Stanford University, Stanford, California., Benson JA; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Shrager JB; Department of Cardiothoracic Surgery, Stanford University, Stanford, California., Bertozzi CR; Departments of Chemistry, Stanford University, Stanford, California., Pitteri SJ; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California., Giaccia AJ; Department of Radiation Oncology, Stanford University, Stanford, California.; Department of Oncology, University of Oxford, Oxford, United Kingdom., Plevritis SK; Department of Biomedical Data Science, Stanford University, Stanford, California.; Department of Radiology, Canary Center for Cancer Early Detection, Palo Alto, California.

Publikováno v: Cancer research [Cancer Res] 2022 Feb 15; Vol. 82 (4), pp. 648-664.

Mapping lung cancer epithelial-mesenchymal transition states and trajectories with single-cell resolution.

Autor: Karacosta LG; Department of Biomedical Data Science, Stanford University, Stanford, USA.; Department of Radiology, Stanford University, Stanford, USA., Anchang B; Department of Biomedical Data Science, Stanford University, Stanford, USA.; Department of Radiology, Stanford University, Stanford, USA., Ignatiadis N; Department of Statistics, Stanford University, Stanford, USA., Kimmey SC; Department of Pathology, Stanford University, Stanford, USA., Benson JA; Department of Cardiothoracic Surgery, Stanford University, Stanford, USA., Shrager JB; Department of Cardiothoracic Surgery, Stanford University, Stanford, USA., Tibshirani R; Department of Biomedical Data Science, Stanford University, Stanford, USA.; Department of Statistics, Stanford University, Stanford, USA., Bendall SC; Department of Pathology, Stanford University, Stanford, USA., Plevritis SK; Department of Biomedical Data Science, Stanford University, Stanford, USA. sylvia.plevritis@stanford.edu.; Department of Radiology, Stanford University, Stanford, USA. sylvia.plevritis@stanford.edu.

Publikováno v: Nature communications [Nat Commun] 2019 Dec 06; Vol. 10 (1), pp. 5587. Date of Electronic Publication: 2019 Dec 06.

Preclinical Analysis of JAA-F11, a Specific Anti-Thomsen-Friedenreich Antibody via Immunohistochemistry and In Vivo Imaging.

Autor: Karacosta LG; For-Robin, Inc, Buffalo, NY. Electronic address: loukia@stanford.edu., Fisk JC; For-Robin, Inc, Buffalo, NY. Electronic address: johnfisk76@yahoo.com., Jessee J; For-Robin, Inc, Buffalo, NY. Electronic address: joejessee0@gmail.com., Tati S; For-Robin, Inc, Buffalo, NY. Electronic address: swethata@buffalo.edu., Turner B; Department of Pathology, University of Rochester, Rochester, NY. Electronic address: Bradley_Turner@URMC.Rochester.edu., Ghazal D; For-Robin, Inc, Buffalo, NY. Electronic address: dialagha@buffalo.edu., Ludwig R; For-Robin, Inc, Buffalo, NY. Electronic address: rludwig3@buffalo.edu., Johnson H; For-Robin, Inc, Buffalo, NY. Electronic address: hollyjoh@buffalo.edu., Adams J; Department of Biotechnical and Clinical Laboratory Sciences, University at Buffalo, Buffalo, NY. Electronic address: jadams33@u.rochester.edu., Sajjad M; Department of Nuclear Medicine, University at Buffalo, Buffalo, NY. Electronic address: msajjad@buffalo.edu., Koury S; Department of Biotechnical and Clinical Laboratory Sciences, University at Buffalo, Buffalo, NY. Electronic address: stvkoury@buffalo.edu., Roy R; Glycovax Pharma Inc., Montreal, Quebec, Canada. Electronic address: rroy@glycovax.com., Olson JR; For-Robin, Inc, Buffalo, NY; Department of Pharmacology and Toxicology, University at Buffalo, Buffalo, NY. Electronic address: jolson@buffalo.edu., Rittenhouse-Olson K; For-Robin, Inc, Buffalo, NY; Department of Biotechnical and Clinical Laboratory Sciences, University at Buffalo, Buffalo, NY. Electronic address: krolson@buffalo.edu.

Publikováno v: Translational oncology [Transl Oncol] 2018 Apr; Vol. 11 (2), pp. 450-466. Date of Electronic Publication: 2018 Feb 22.