Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kara Y. Chan"'
Autor:
Linya Wang, Pankaj Garg, Kara Y. Chan, Tom Z. Yuan, Ana G. Lujan Hernandez, Zhen Han, Sean M. Peterson, Emily Tuscano, Crystal Safavi, Eric Kwan, Mouna Villalta, Melina Mathur, Joyce Lai, Fumiko Axelrod, Colby A. Souders, Chloe Emery, Aaron K. Sato
Publikováno v:
PLoS ONE, Vol 19, Iss 6 (2024)
Externí odkaz:
https://doaj.org/article/19d9881e92ee441db2ab1b748136eaae
Autor:
Yijie Wang, Yan Chen, Chenliang Wang, Mingming Yang, Yanan Wang, Lei Bao, Jennifer E. Wang, BongWoo Kim, Kara Y. Chan, Weizhi Xu, Emanuela Capota, Janice Ortega, Deepak Nijhawan, Guo-Min Li, Weibo Luo, Yingfei Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Replication stress is associated with cancer formation and progression. Here the authors reveal that the macrophage migration inhibitory factor (MIF) functions as 3’ flap nuclease involved in resolving replication stress affecting overall tumor pro
Externí odkaz:
https://doaj.org/article/e6e52889e32e4ede9a3a9d521e8846bc
Autor:
Linya Wang, Sean M. Peterson, Ana Lujan, Kara Y. Chan, Cameron F. Hu, Mouna Villalta, Tom Z. Yuan, Zhen Han, Marisa Yang, Vishwas Prabhu, Tammy Htoy, Paul VanDyke, Carson Holliday, Hector Franco, Hansika Wadhwa, Hoa Giang, Ryan Stafford, Fumiko Axelrod, Aaron Sato
Publikováno v:
Cancer Research. 83:2649-2649
Wnt signaling plays an important role in embryonic development and tumorigenesis. These biological effects are exerted by activation of the β-catenin/TCF transcription complex and consequent regulation of a set of downstream genes. Dickkopf WNT Sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb7179b0e397811781bbde259ab20d94
https://doi.org/10.1158/1538-7445.am2023-2649
https://doi.org/10.1158/1538-7445.am2023-2649
Autor:
Linya Wang, Tom Z. Yuan, Mouna Villalta, Zhen Han, Hansika Wadhwa, Kara Y. Chan, Marisa Yang, Tammy Htoy, Paul VanDyke, Carson Holliday, Hector Franco, Hoa Giang, Fumiko Axelrod, Aaron Sato
Publikováno v:
Cancer Research. 83:1531-1531
Checkpoint inhibitors represent a major advance in cancer immunotherapy, and combinatorial immunotherapies with secondary drivers of anti-tumor immunity provide beneficial effects for patients that do not show a strong endogenous immune response. CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ac2e0db61bf9d1a52a7935784744fd5
https://doi.org/10.1158/1538-7445.am2023-1531
https://doi.org/10.1158/1538-7445.am2023-1531
Publikováno v:
The Journal of Biological Chemistry
Huntington's disease (HD), a neurodegenerative disease characterized by progressive dementia, psychiatric problems, and chorea, is known to be caused by CAG repeat expansions in the HD gene HTT. However, the mechanism of this pathology is not fully u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebae6f95d3f821dae8a620705cf59bbb
https://pubmed.ncbi.nlm.nih.gov/34473992
https://pubmed.ncbi.nlm.nih.gov/34473992
Autor:
Yingfei Wang, Emanuela Capota, Bong Woo Kim, Weizhi Xu, Kara Y. Chan, Weibo Luo, Guo Min Li, Deepak Nijhawan, Yanan Wang, Yijie Wang, Lei Bao, Jennifer E. Wang, Mingming Yang, Janice Ortega, Chenliang Wang, Yan Chen
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
How cancer cells cope with high levels of replication stress during rapid proliferation is currently unclear. Here, we show that macrophage migration inhibitory factor (MIF) is a 3’ flap nuclease that translocates to the nucleus in S phase. Poly(AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b307c45fbf426edb48e82ccb8d7c36d5
http://europepmc.org/articles/PMC8134555
http://europepmc.org/articles/PMC8134555
Publikováno v:
Nucleic Acids Research
CTG circle CAG repeat expansions cause at least twelve inherited neurological diseases. Expansions require the presence, not the absence, of the mismatch repair protein MutS beta (Msh2-Msh3 heterodimer). To evaluate properties of MutS beta that drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac00076f2c584a0c975adf2ebb7e185
http://hdl.handle.net/10379/12240
http://hdl.handle.net/10379/12240
Publikováno v:
Photochemistry and photobiology. 89(2)
The fluorescence lifetimes of the estrogens, estrone, 17β-estradiol and 17α-ethinylestradiol, were studied in various solvents. The fluorescence lifetimes of 17β-estradiol and 17α-ethinylestradiol decreased from 4.7 to 0.9 ns as the solvent hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0e0816a8992035c3168a64ef91ca6d6
https://pubmed.ncbi.nlm.nih.gov/23094977
https://pubmed.ncbi.nlm.nih.gov/23094977
Publikováno v:
Photochemistry and photobiology. 88(2)
Absorption and emission yields for estrone and 17β-estradiol were measured in a variety of room temperature solvents. Molar extinction coefficients were found to not vary as a function of solvent, while fluorescence yields were found to be significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b53c5927cb9831876ae8319253e04f49
https://pubmed.ncbi.nlm.nih.gov/22191459
https://pubmed.ncbi.nlm.nih.gov/22191459