Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Kara W Chew"'
Autor:
Tin Phan, Carolin Zitzmann, Kara W Chew, Davey M Smith, Eric S Daar, David A Wohl, Joseph J Eron, Judith S Currier, Michael D Hughes, Manish C Choudhary, Rinki Deo, Jonathan Z Li, Ruy M Ribeiro, Ruian Ke, Alan S Perelson, ACTIV-2/A5401 Study Team
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011680 (2024)
To mitigate the loss of lives during the COVID-19 pandemic, emergency use authorization was given to several anti-SARS-CoV-2 monoclonal antibody (mAb) therapies for the treatment of mild-to-moderate COVID-19 in patients with a high risk of progressin
Externí odkaz:
https://doaj.org/article/78108cfe10f347ff8cf97ead03163c63
Autor:
Sergie Antoniak, Charles S Chasela, Morgan Julie Freiman, Yulia Stopolianska, Tetiana Barnard, Malini M Gandhi, Maria Liulchuk, Zhanna Tsenilova, Tretiakov Viktor, Jeri Dible, Constance Wose Kinge, Francis Akpan, Thomas Minior, Ntombi Sigwebela, Sofiane Mohamed, Matthiue Barralon, Fadzai Marange, Clint Cavenaugh, Charles Vander Horst, Svitlana Antonyak, Thembisile Xulu, Kara W Chew, Ian Sanne, Sydney Rosen, for EQUIP Health
Publikováno v:
JGH Open, Vol 6, Iss 12, Pp 894-903 (2022)
Abstract Background and Aim To demonstrate the use of a standard dose of ledipasvir (LDV) and sofosbuvir (SOF), with or without ribavirin, to treat hepatitis C and hepatitis C/HIV co‐infection in Ukraine. Methods Eligible HCV viraemic adults from t
Externí odkaz:
https://doaj.org/article/e28414838a3e4a78882d07b1520eb1f7
Autor:
Deanna Ware, Frank J Palella, Kara W Chew, M Reuel Friedman, Gypsyamber D'Souza, Ken Ho, Michael Plankey
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203890 (2018)
Rates of aging-related comorbidities, which require targeted medications to treat, have been shown to be increased among persons living with HIV compared with uninfected counterparts. Polypharmacy is generally defined as the concurrent use of 5 or mo
Externí odkaz:
https://doaj.org/article/a395165b21b146f1b4d575706cd74891
Autor:
Christopher J. Berg, Bobby Patel, Maxwell Reynolds, Mirela Tuzovic, Kara W. Chew, Jason J. Sico, Debika Bhattacharya, Adeel A. Butt, Joseph K. Lim, Roger J. Bedimo, Sheldon T. Brown, John S. Gottdiener, Alberta L. Warner, Matthew S. Freiberg, Kaku A. So-Armah, Kim-Lien Nguyen
Publikováno v:
The American Journal of Cardiology. 186:50-57
Human immunodeficiency virus (HIV) infection is associated with subclinical cardiomyopathy, diastolic dysfunction, and increased risk of cardiovascular death. However, the relationship between left atrial (LA) mechanics and left ventricular (LV) dias
Autor:
Yijia Li, Linda J Harrison, Kara W Chew, Judy S Currier, David A Wohl, Eric S Daar, Teresa H Evering, Ryan Wu, Mark Giganti, Justin Ritz, Arzhang Cyrus Javan, Robert W Coombs, Carlee Moser, Michael D Hughes, Joseph J Eron, Davey M Smith, Jonathan Z Li
Publikováno v:
Clinical Infectious Diseases. 76:734-737
Acute Coronavirus Disease 2019 symptoms limit daily activities, but little is known about its association with severe acute respiratory syndrome coronavirus 2 viral burden. In this exploratory analysis of placebo recipients in the ACTIV-2/A5401 platf
Autor:
Kara W Chew, Kunling Wu, Katherine Tassiopoulos, Frank J Palella, Susanna Naggie, Netanya S Utay, Edgar T Overton, Mark Sulkowski
Publikováno v:
Clinical Infectious Diseases. 76:e571-e579
Background We sought to characterize in people with human immunodeficiency virus (PWH) the potential etiologies of elevated alanine aminotransferase (ALT) levels, which are common and often unexplained. Methods Participants from the longitudinal obse
Autor:
Akif Altinbas, Jacinta A Holmes, Shadi Salloum, Anna Lidofsky, Nadia Alatrakchi, Ma Somsouk, Peter Hunt, Steven Deeks, Kara W Chew, Georg Lauer, Annie Kruger, Wenyu Lin, Raymond T Chung
Publikováno v:
Biomarkers in Medicine. 16:839-846
Background: Lysil oxidase like enzyme-2 (LOXL-2) and TNC-C play important roles in organ fibrosis. We assessed circulating LOXL-2 and TNC-C levels and their relationship to fibrosis severity in HIV- and/or HCV-infected individuals. Methods: Healthy c
Autor:
Carlee B Moser, Kara W Chew, Mark J Giganti, Jonathan Z. Li, Evgenia Aga, Justin Ritz, Alex Greninger, Arzhang Cyrus Javan, Rachel A Bender Ignacio, Eric S Daar, David A Wohl, Judith S Currier, Joseph J Eron, Davey M Smith, Michael D Hughes
Publikováno v:
medRxiv
Most clinical trials evaluating COVID-19 therapeutics include assessments of antiviral activity. In recently completed outpatient trials, changes in nasal SARS-CoV-2 RNA levels from baseline were commonly assessed using analysis of covariance (ANCOVA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::444c597a5db7472b83d816f388ab8361
https://europepmc.org/articles/PMC10055451/
https://europepmc.org/articles/PMC10055451/
Autor:
Oriol Mitjà, Gilmar Reis, David R. Boulware, Adam M. Spivak, Ammar Sarwar, Christine Johnston, Brandon Webb, Michael D. Hill, Davey Smith, Peter Kremsner, Marla Curran, David Carter, Jim Alexander, Marc Corbacho, Todd C. Lee, Katherine Huppler Hullsiek, Emily G. McDonald, Rachel Hess, Michael Hughes, Jared M. Baeten, Ilan Schwartz, Luanne Metz, Lawrence Richer, Kara W. Chew, Eric Daar, David Wohl, Michael Dunne
Hydroxychloroquine (HCQ) was initially promoted as an oral therapy for early treatment of coronavirus disease 2019 (COVID-19). Conventional meta-analyses cannot fully address the heterogeneity of different designs and outcomes of randomized controlle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a9e1f7e4d16a401f9d02f3b7cae646
Autor:
Louis S. Matza, Katie D. Stewart, April N. Naegeli, Kayla M. Mills, Karin S. Coyne, Kara W. Chew, Michael D. Hughes, Davey M. Smith
Publikováno v:
Journal of patient-reported outcomes, vol 7, iss 1
Background Patient-reported outcome measures are needed to assess the impact of treatments for COVID-19 on symptoms. The ACTIV-2 COVID-19 Symptom Diary (ACSD) is being used in the ongoing Accelerating COVID-19 Therapeutic Interventions and Vaccines-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efba08547b0cc5af8519f95efe5b297
https://escholarship.org/uc/item/3qj6b9zn
https://escholarship.org/uc/item/3qj6b9zn