Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kara S. Bell"'
Autor:
Felicity E. Lumb, James Doonan, Kara S. Bell, Miguel A. Pineda, Marlene Corbet, Colin J. Suckling, Margaret M. Harnett, William Harnett
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract ES-62, a glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae, subverts host immune responses towards anti-inflammatory phenotypes by virtue of covalently attached phosphorylcholine (PC). The PC dictates that ES-
Externí odkaz:
https://doaj.org/article/630b811b03324ca2ba57f8104374c764
Autor:
James Doonan, David Thomas, Michelle H. Wong, Hazel J. Ramage, Lamyaa Al-Riyami, Felicity E. Lumb, Kara S. Bell, Karen J. Fairlie-Clarke, Colin J. Suckling, Kathrin S. Michelsen, Hui-Rong Jiang, Anne Cooke, Margaret M. Harnett, William Harnett
Publikováno v:
Molecules, Vol 23, Iss 10, p 2669 (2018)
Parasitic helminths and their isolated secreted products show promise as novel treatments for allergic and autoimmune conditions in humans. Foremost amongst the secreted products is ES-62, a glycoprotein derived from Acanthocheilonema viteae, a filar
Externí odkaz:
https://doaj.org/article/d5805fddbabc4db1868d1305e8b5be66
Autor:
Dimity H. Ball, Hwee Kee Tay, Kara S. Bell, Michelle L. Coates, Lamyaa Al-Riyami, Justyna Rzepecka, William Harnett, Margaret M. Harnett
Publikováno v:
Journal of Parasitology Research, Vol 2013 (2013)
ES-62, an immunomodulator secreted by filarial nematodes, exhibits therapeutic potential in mouse models of allergic inflammation, at least in part by inducing the desensitisation of FcεRI-mediated mast cell responses. However, in addition to their
Externí odkaz:
https://doaj.org/article/376ffc3c319d447fa550805c2bcd3e0d
Autor:
Russell J, Eason, Kara S, Bell, Fraser A, Marshall, David T, Rodgers, Miguel A, Pineda, Christina N, Steiger, Lamyaa, Al-Riyami, William, Harnett, Margaret M, Harnett
Publikováno v:
Scientific Reports
We have previously shown that ES-62, a phosphorylcholine (PC)-containing glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae targets dendritic cell (DC) responses, specifically by suppressing TLR4 signalling to inhibit T
Autor:
Kara S, Bell, Lamyaa, Al-Riyami, Felicity E, Lumb, Graham J, Britton, Alastair W, Poole, Christopher M, Williams, Ursula, Braun, Michael, Leitges, Margaret M, Harnett, William, Harnett
Publikováno v:
Immunology Letters
Highlights • Knock out mice have been used to explore the role of PKCs in mast cell (MC) function. • Individual PKC isoforms may positively or negatively regulate MC cytokine responses. • Certain PKC isoforms in MCs are targeted by the parasiti
Autor:
Hwee Kee Tay, Justyna Rzepecka, Michelle L. Coates, Margaret M. Harnett, Kara S. Bell, William Harnett, Lamyaa Al-Riyami, Dimity H. Ball
Publikováno v:
Journal of Parasitology Research
Journal of Parasitology Research, Vol 2013 (2013)
Journal of Parasitology Research, Vol 2013 (2013)
ES-62, an immunomodulator secreted by filarial nematodes, exhibits therapeutic potential in mouse models of allergic inflammation, at least in part by inducing the desensitisation of FcεRI-mediated mast cell responses. However, in addition to their