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Autor:
Shayne C. Gad, Leslie Anne Eagle, Danielle R Stackhouse Pallman, Philip A. Downing, Catherine Shoemake, Richard E. Seals, Jennifer Daly, Charles B. Spainhour, Kara Polhamus, Alain Stricker-Krongrad
Publikováno v:
International journal of toxicology. 35(2)
Formulation of nonclinical evaluations is a challenge, with the fundamental need to achieve multiples of the clinical exposure complicated by differences in species and routes of administration-specific tolerances, depending on concentrations, volume