Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kara N Thomas"'
Autor:
Samantha L. Higgins, Sanat S. Bhadsavle, Matthew N. Gaytan, Kara N. Thomas, Michael C. Golding
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Although dose-response analyses are a fundamental tool in developmental toxicology, few studies have examined the impacts of toxicant dose on the non-genetic paternal inheritance of offspring disease and dysgenesis. In this study, we used geometric m
Externí odkaz:
https://doaj.org/article/b73c04efed8842c291b30ca674b11847
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Externí odkaz:
https://doaj.org/article/21158086210f4d4899fa9d8a52c8c541
Autor:
Kara N. Thomas, Nimisha Srikanth, Sanat S. Bhadsavle, Kelly R. Thomas, Katherine N. Zimmel, Alison Basel, Alexis N. Roach, Nicole A. Mehta, Yudhishtar S. Bedi, Michael C. Golding
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/cc5084375bb0487faa5fc0f82732938d
Autor:
Yudhishtar S. Bedi, Haiqing Wang, Kara N. Thomas, Alison Basel, Julien Prunier, Claude Robert, Michael C. Golding
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Using a mouse model, studies by our group reveal that paternal preconception alcohol intake affects offspring fetal-placental growth, with long-lasting consequences on adult metabolism. Here, we tested the hypothesis that chronic preconcepti
Externí odkaz:
https://doaj.org/article/1f16f170932a4db788f247f21c0e5a04
Publikováno v:
Epigenetics & Chromatin, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Background Paternal lifestyle choices and male exposure history have a critical influence on the health and fitness of the next generation. Accordingly, defining the processes of germline programming is essential to resolving how the epigene
Externí odkaz:
https://doaj.org/article/55a645d872fb4af197c7bc0ab706c993
Autor:
Richard C. Chang, Kara N. Thomas, Nicole A. Mehta, Kylee J. Veazey, Scott E. Parnell, Michael C. Golding
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-16 (2021)
Abstract Background A critical question emerging in the field of developmental toxicology is whether alterations in chromatin structure induced by toxicant exposure control patterns of gene expression or, instead, are structural changes that are part
Externí odkaz:
https://doaj.org/article/d04f2596db574a03bd7ad0daa9753dd6
Autor:
Kara N. Thomas, Katherine N. Zimmel, Alison Basel, Alexis N. Roach, Nicole A. Mehta, Kelly R. Thomas, Luke J. Dotson, Yudhishtar S. Bedi, Michael C. Golding
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Hormesis refers to graded adaptive responses to harmful environmental stimuli where low-level toxicant exposures stimulate tissue growth and responsiveness while, in contrast, higher-level exposures induce toxicity. Although the intergenerational inh
Externí odkaz:
https://doaj.org/article/c31b73da319244fb89966aa845bb534e
Publikováno v:
Molecular Metabolism, Vol 30, Iss , Pp 161-172 (2019)
Objectives: Paternally inherited alterations in epigenetic programming are emerging as relevant factors in numerous disease states, including the growth and metabolic defects observed in fetal alcohol spectrum disorders. In rodents, chronic paternal
Externí odkaz:
https://doaj.org/article/c92434f059ea40e088dde86d444b11d5
Autor:
Alexis N Roach, Katherine N Zimmel, Kara N Thomas, Alison Basel, Sanat S Bhadsavle, Michael C Golding
Publikováno v:
Molecular Human Reproduction. 29
Increasingly, couples struggling with fertility turn to assisted reproductive techniques, including IVF, to have children. Despite the demonstrated influence of periconception male health and lifestyle choices on offspring development, studies examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83f9368e0d22babb5fafb066582ee4a5
https://doi.org/10.1093/molehr/gaad002
https://doi.org/10.1093/molehr/gaad002
Autor:
Yudhishtar S, Bedi, Haiqing, Wang, Kara N, Thomas, Alison, Basel, Julien, Prunier, Claude, Robert, Michael C, Golding
Publikováno v:
Scientific reports. 12(1)
Using a mouse model, studies by our group reveal that paternal preconception alcohol intake affects offspring fetal-placental growth, with long-lasting consequences on adult metabolism. Here, we tested the hypothesis that chronic preconception male a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0f20e3c34bd157594cb790bd7ba116fc
https://pubmed.ncbi.nlm.nih.gov/35614060
https://pubmed.ncbi.nlm.nih.gov/35614060