Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kara L. Bane"'
Autor:
Erica M. Sparkenbaugh, Michael W. Henderson, Megan Miller-Awe, Christina Abrams, Anton Ilich, Fatima Trebak, Nirupama Ramadas, Shantel Vital, Dillon Bohinc, Kara L. Bane, Chunsheng Chen, Margi Patel, Michael Wallisch, Thomas Renné, Andras Gruber, Brian Cooley, David Gailani, Malgorzata Kasztan, Gregory M. Vercellotti, John D. Belcher, Felicity E. Gavins, Evi X. Stavrou, Nigel S. Key, Rafal Pawlinski
Publikováno v:
Blood. 141:1871-1883
Data are available on request from the corresponding author, R. Pawlinski (rafal_pawlinski@med.unc.edu). The online version of this article contains a data supplement. The American Society of Hematology A hypercoagulable state, chronic inflammation,
Autor:
Lewis J. Hardy, Dillon Bohinc, Kara L. Bane, Samantha L. Heal, Emma Hethershaw, Majid Ali, Thomas Palmer-Dench, Richard Foster, Colin Longstaff, Thomas Renné, Evi X. Stavrou, Helen Philippou
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:814-827
Autor:
Michelle A. Cruz, Dillon Bohinc, Elizabeth A. Andraska, Jurgis Alvikas, Shruti Raghunathan, Nicole A. Masters, Nadine D. van Kleef, Kara L. Bane, Kathryn Hart, Kathryn Medrow, Michael Sun, Haitao Liu, Shannon Haldeman, Ankush Banerjee, Emma M. Lessieur, Kara Hageman, Agharnan Gandhi, Maria de la Fuente, Marvin T. Nieman, Timothy S. Kern, Coen Maas, Steven de Maat, Keith B. Neeves, Matthew D. Neal, Anirban Sen Gupta, Evi X. Stavrou
Publikováno v:
Nature nanotechnology, vol 17, iss 9
Nat Nanotechnol
Nat Nanotechnol
Targeted drug delivery to disease-associated activated neutrophils can provide novel therapeutic opportunities while avoiding systemic effects on immune functions. We created a nanomedicine platform that uniquely utilizes an α(1)-antitrypsin-derived
Autor:
Kara L. Bane, Evi X. Stavrou, Pedram Mohseni, Aman Opneja, Brigid Wilson, Debnath Maji, Michael A. Suster
Publikováno v:
Thromb Haemost
Background There are acute settings where assessing the anticoagulant effect of direct oral anticoagulants (DOACs) can be useful. Due to variability among routine coagulation tests, there is an unmet need for an assay that detects DOAC effects within
Autor:
Michelle A, Cruz, Dillon, Bohinc, Elizabeth A, Andraska, Jurgis, Alvikas, Shruti, Raghunathan, Nicole A, Masters, Nadine D, van Kleef, Kara L, Bane, Kathryn, Hart, Kathryn, Medrow, Michael, Sun, Haitao, Liu, Shannon, Haldeman, Ankush, Banerjee, Emma M, Lessieur, Kara, Hageman, Agharnan, Gandhi, Maria, de la Fuente, Marvin T, Nieman, Timothy S, Kern, Coen, Maas, Steven, de Maat, Keith B, Neeves, Matthew D, Neal, Anirban, Sen Gupta, Evi X, Stavrou
Publikováno v:
Nature nanotechnology. 17(9)
Targeted drug delivery to disease-associated activated neutrophils can provide novel therapeutic opportunities while avoiding systemic effects on immune functions. We created a nanomedicine platform that uniquely utilizes an α
Critical role of a survivin/TGF-β/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cells.
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e61896 (2013)
Survivin is a unique member of the inhibitor of apoptosis (IAP) proteins that is overexpressed in numerous cancers through poorly defined mechanisms. One such mechanism may be through constitutive activation of the insulin-like growth factor-I (IGF-I
Externí odkaz:
https://doaj.org/article/df90f3df9bdc44a4909e72ecaa5e53b4
Autor:
Sarah L. Corum, Kara L. Bane, Kyung Song, David Danielpour, Hung Ying Kao, Eswar Shankar, Hui Wang
Publikováno v:
Journal of Biological Chemistry. 291:5512-5526
The transcription factor c-Fos controls many important cellular processes, including cell growth and apoptosis. c-Fos expression is rapidly elevated in the prostate upon castration-mediated androgen withdrawal through an undefined mechanism. Here we
Publikováno v:
Blood. 134:2384-2384
Host and Tumor Factor XII Drive Ovarian Cancer Maintenance and Progression Introduction . Epithelial ovarian cancer (EOC) is the leading cause of cancer death in women.Effective strategies to treat this disease are lacking due to the complexity of pa
Autor:
Sudeh Izadmehr, Omar Alhalabi, Alvin H. Schmaier, Kara L. Bane, Anirban Sen Gupta, Agharnan Gandhi, George R. Dubyak, Cindy C. Reynolds, Andy T. Long, Alona Merkulova, Wen Mei Yu, Howard J. Meyerson, Lalitha Nayak, Clément Naudin, Michele M. Mumaw, Marvin T. Nieman, Umut A. Gurkan, Cheng-Kui Qu, Erdem Kucukal, Adina Brett-Morris, Thomas Renné, Evi X. Stavrou, Chao Fang
Coagulation factor XII (FXII) deficiency is associated with decreased neutrophil migration, but the mechanisms remain uncharacterized. Here, we examine how FXII contributes to the inflammatory response. In 2 models of sterile inflammation, FXII-defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3612c60ec3b521e147d3fff7a7887db
https://europepmc.org/articles/PMC5824869/
https://europepmc.org/articles/PMC5824869/