Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kara L O'Brien"'
Autor:
So-Yon Lim, Tiffany Chan, Rebecca S Gelman, James B Whitney, Kara L O'Brien, Dan H Barouch, David B Goldstein, Barton F Haynes, Norman L Letvin
Publikováno v:
PLoS Genetics, Vol 6, Iss 6, p e1000997 (2010)
CCL3 is a ligand for the HIV-1 co-receptor CCR5. There have recently been conflicting reports in the literature concerning whether CCL3-like gene (CCL3L) copy number variation (CNV) is associated with resistance to HIV-1 acquisition and with both vir
Externí odkaz:
https://doaj.org/article/60c4dc61353044759a39108016bac706
Publikováno v:
Natural Areas Journal. 35:18-25
Habitat in national parks is periodically disturbed for road maintenance, and few revegetation protocols of known financial cost exist for this disturbance, especially in deserts where extreme environments constrain natural revegetation. In Saguaro N
Autor:
Annalena La Porte, Kara L. O'Brien, Angela Carville, Keith G. Mansfield, Dan H. Barouch, Jinyan Liu, Katherine Masek-Hammerman, Hualin Li, James B. Whitney, Peter Abbink
Publikováno v:
Journal of Virology. 84:9810-9816
Post hoc analysis of the phase 2b Step study evaluating a recombinant adenovirus serotype 5 (rAd5)-based HIV-1 vaccine candidate suggested a potential increased risk of HIV-1 acquisition in subjects who were baseline Ad5 seropositive and uncircumcise
Autor:
Lori F. Maxfield, Katherine Backus, Kara L. O'Brien, Sharon L. King, Diana M. Lynch, Sarah L. Clark, Ying-Hua B. Sun, Mark J. Muldoon, Will Fischer, James J. Szinger, Peter Abbink, James R. Perry, Bette T. Korber, Michael S. Seaman, Angela Carville, Annalena La Porte, Ambryice M. Riggs, Nathaniel L. Simmons, Keith G. Mansfield, Dan H. Barouch
Publikováno v:
Nature medicine
The worldwide diversity of HIV-1 presents an unprecedented challenge for vaccine development 1-2. Antigens derived from natural HIV-1 sequences have elicited only limited breadth of cellular immune responses in nonhuman primate studies and clinical t
Autor:
Dan H. Barouch, Keith G. Mansfield, Bonnie A. Ewald, Anna R. Thorner, Peter Abbink, Kara L. O'Brien, Angela Carville, Ronald Vogels, Shirley Smits, Angelique A. C. Lemckert, Lennart Holterman, Irma Damen, Jaap Goudsmit, Diana M. Lynch, Matthew Denholtz, Menzo J. E. Havenga
Publikováno v:
Journal of virology, 81(9), 4654-4663. American Society for Microbiology
Recombinant adenovirus serotype 5 (rAd5) vector-based vaccines are currently being developed for both human immunodeficiency virus type 1 and other pathogens. The potential limitations associated with rAd5 vectors, however, have led to the constructi
Autor:
Ying-Hua B. Sun, Jaap Goudsmit, Natalie A. Hutnick, Danilo R. Casimiro, Joern E. Schmitz, Jinyan Liu, Sheri Dubey, Dan H. Barouch, Michelle A. Lifton, Michael N. Robertson, Michael R. Betts, Sharon L. King, Kara L. O'Brien, John W. Shiver
Publikováno v:
Nature medicine, 15(8), 873-875. Nature Publishing Group
Nature medicine
Nature medicine
The immunologic basis for the potential enhanced HIV-1 acquisition in adenovirus serotype 5 (Ad5)-seropositive individuals who received the Merck recombinant Ad5 HIV-1 vaccine in the STEP study remains unclear. Here we show that baseline Ad5-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb1de8b5b2246e4356892ea21fcc4134
https://pure.amc.nl/en/publications/adenovirusspecific-immunity-after-immunization-with-an-ad5-hiv1-vaccine-candidate-in-humans(87821f1b-362c-4ede-bbb8-f5f3c27e71e5).html
https://pure.amc.nl/en/publications/adenovirusspecific-immunity-after-immunization-with-an-ad5-hiv1-vaccine-candidate-in-humans(87821f1b-362c-4ede-bbb8-f5f3c27e71e5).html
Autor:
Jinyan Liu, Jaap Goudsmit, Gary Landucci, Annalena La Porte, Angela Carville, Rory Coffey, Kara L. O'Brien, Maria G. Pau, Keith G. Mansfield, Diana M. Lynch, Michael S. Seaman, Menzo J. E. Havenga, Ambryice M. Riggs, Donald N. Forthal, Dan H. Barouch, Nathaniel L. Simmons, Lauren E. Grandpre, Peter Abbink, David C. Montefiori
Publikováno v:
Nature, 457(7225), 87-91. Nature Publishing Group
Nature, January, 7225, 457, 87-91
Liu, J; O'Brien, KL; Lynch, DM; Simmons, NL; La Porte, A; Riggs, AM; et al.(2009). Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature, 457(7225), 87-91. doi: 10.1038/nature07469. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/006375j7
Nature
Nature, January, 7225, 457, 87-91
Liu, J; O'Brien, KL; Lynch, DM; Simmons, NL; La Porte, A; Riggs, AM; et al.(2009). Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys. Nature, 457(7225), 87-91. doi: 10.1038/nature07469. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/006375j7
Nature
A recombinant adenovirus serotype 5 (rAd5) vector-based vaccine for HIV-1 has recently failed in a phase 2b efficacy study in humans. Consistent with these results, preclinical studies have demonstrated that rAd5 vectors expressing simian immunodefic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437147c27caa4fccf2c95f6e99503c4e
https://pure.amc.nl/en/publications/immune-control-of-an-siv-challenge-by-a-tcellbased-vaccine-in-rhesus-monkeys(d0d20567-246c-4d8d-94d0-bc0792c1cbb7).html
https://pure.amc.nl/en/publications/immune-control-of-an-siv-challenge-by-a-tcellbased-vaccine-in-rhesus-monkeys(d0d20567-246c-4d8d-94d0-bc0792c1cbb7).html
Autor:
Prakash Jeena, Ronald Vogels, Athmanundh Dilraj, Jaap Goudsmit, Kara L. O'Brien, Anna R. Thorner, Lisa M. McNally, Gerrit Jan Weverling, Patricia E. Swanson, Jorn Kaspers, Lennart Holterman, Andrew Bates, Angelique A. C. Lemckert, Dan H. Barouch, Anjali Nanda, Soren Jepsen, Menzo J. E. Havenga, Peter Abbink
Publikováno v:
Journal of clinical microbiology, 44(10), 3781-3783. American Society for Microbiology
We assessed neutralizing antibody titers to adenovirus serotype 5 (Ad5) and six rare adenovirus serotypes, serotypes 11, 35, 50, 26, 48, and 49, in pediatric populations in sub-Saharan Africa. We observed a clear age dependence of Ad5-specific neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d96fe07c4e0c104f2df79e386bb8ac
https://pure.amc.nl/en/publications/age-dependence-of-adenovirusspecific-neutralizing-antibody-titers-in-individuals-from-subsaharan-africa(95f815da-6455-4123-932b-822617f8c171).html
https://pure.amc.nl/en/publications/age-dependence-of-adenovirusspecific-neutralizing-antibody-titers-in-individuals-from-subsaharan-africa(95f815da-6455-4123-932b-822617f8c171).html
Autor:
Kara L. O'Brien, A La Porte, Maria Pau, Robert Tucker, R Dolin, Peter Abbink, Lindsey R. Baden, Seaman, Dan H. Barouch, M Weitjens, E Choi, Jaap Goudsmit
Publikováno v:
Retrovirology