Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Kara L Britt"'
Autor:
Nathan J Godde, Julie M Sheridan, Lorey K Smith, Helen B Pearson, Kara L Britt, Ryan C Galea, Laura L Yates, Jane E Visvader, Patrick O Humbert
Publikováno v:
PLoS Genetics, Vol 10, Iss 5, p e1004323 (2014)
Polarity coordinates cell movement, differentiation, proliferation and apoptosis to build and maintain complex epithelial tissues such as the mammary gland. Loss of polarity and the deregulation of these processes are critical events in malignant pro
Externí odkaz:
https://doaj.org/article/4654c8576bb2422e842ccdba989b01a7
Autor:
Louie Ye, Robyn Mayberry, Camden Y Lo, Kara L Britt, Edouard G Stanley, Andrew G Elefanty, Caroline E Gargett
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21136 (2011)
BACKGROUND: Recent studies have identified stem/progenitor cells in human and mouse uterine epithelium, which are postulated to be responsible for tissue regeneration and proliferative disorders of human endometrium. These progenitor cells are though
Externí odkaz:
https://doaj.org/article/c49d54c8c7014be3a2210e55d76248e3
Autor:
Elena A. Takano, Melissa M. Younes, Katie Meehan, Lisa Spalding, Max Yan, Prue Allan, Stephen B. Fox, Andy Redfern, David Clouston, Graham G. Giles, Elizabeth L. Christie, Robin L. Anderson, Magnus Zethoven, Kelly-Anne Phillips, Kylie Gorringe, Kara L. Britt
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Triple negative BCa (TNBC) is defined by a lack of expression of estrogen (ERα), progesterone (PgR) receptors and human epidermal growth factor receptor 2 (HER2) as assessed by protein expression and/or gene amplification. It mak
Externí odkaz:
https://doaj.org/article/8425c7a02adc4bc79190c37d150123d5
Autor:
Helen Tower, Genevieve Dall, Ashleigh Davey, Melanie Stewart, Patrick Lanteri, Meagan Ruppert, Maria Lambouras, Ibraheem Nasir, Serene Yeow, Phillip K. Darcy, Wendy V. Ingman, Belinda Parker, Nicole M. Haynes, Kara L. Britt
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Breast cancer (BCa) incidence increases following aberrant hormone exposure, which has been linked to direct effects on estrogen receptor (ER)+ mammary epithelium. While estrogen exposure during mammary involution has been shown to drive tum
Externí odkaz:
https://doaj.org/article/49ec8610163947a8b32e9c455e48f421
Autor:
Maria Lambouras, Charlotte Roelofs, Melrine Pereira, Emily Gruber, Jessica L. Vieusseux, Patrick Lanteri, Cameron N. Johnstone, Fenella Muntz, Sandra O’Toole, Lisa M. Ooms, Christina A. Mitchell, Robin L. Anderson, Kara L. Britt
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5666 (2023)
Estrogen receptor-positive breast cancers (ER+ BCas) are the most common form of BCa and are increasing in incidence, largely due to changes in reproductive practices in recent decades. Tamoxifen is prescribed as a component of standard-of-care endoc
Externí odkaz:
https://doaj.org/article/dd936a7e8fe74bbba48736a7c009957e
Autor:
Maria Lambouras, Kara L. Britt
Publikováno v:
Current Opinion in Endocrine and Metabolic Research. 15:49-56
The response of mammary stem and progenitor cell subsets to reproductive hormones (estrogen and progesterone) may provide insight into the mechanisms leading to hormone-mediated breast cancer development. Here we review identification of these cells,
Autor:
Heather J. Bray, Jennifer Stone, Lillith Litchfield, Kara L. Britt, John L. Hopper, Wendy V. Ingman
Publikováno v:
Challenges; Volume 13; Issue 1; Pages: 7
The COVID-19 pandemic caused many scientific conferences to move online, posing a great challenge for scientific communication. This change offers potential advantages and disadvantages for inclusion, diversity, and scientific advancement. Here, we a
Autor:
Maddison Archer, Pallave Dasari, David Walsh, Kara L. Britt, Andreas Evdokiou, Wendy V. Ingman
Publikováno v:
Journal of Clinical Medicine; Volume 11; Issue 3; Pages: 799
Journal of Clinical Medicine, Vol 11, Iss 799, p 799 (2022)
Journal of Clinical Medicine, Vol 11, Iss 799, p 799 (2022)
Mammographic density is associated with a 4–6-fold increase in breast cancer risk independent of age and BMI. High mammographic density is characterized by breast tissue with high proportions of stroma comprised of fibroblasts, collagen, and immune
Autor:
Robin L. Anderson, Mandy J. Ludford-Menting, Alan Ashworth, Jessica L. Vieusseux, Mark Shackleton, Kara L. Britt, Nathan Godde, Yashar Seyed-Razavi, Sarah M. Russell, Genevieve V. Dall, Gail P. Risbridger
Publikováno v:
Breast Cancer Research and Treatment. 183:565-575
Breast cancer (BCa) mortality is decreasing with early detection and improvement in therapies. The incidence of BCa, however, continues to increase, particularly estrogen-receptor-positive (ER +) subtypes. One of the greatest modifiers of ER + BCa ri
Publikováno v:
Nature Reviews Cancer. 20:417-436
Despite decades of laboratory, epidemiological and clinical research, breast cancer incidence continues to rise. Breast cancer remains the leading cancer-related cause of disease burden for women, affecting one in 20 globally and as many as one in ei