Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kara E. Malcolm"'
Autor:
Naval Daver, Pau Montesinos, Ahmed Aribi, Giovanni Marconi, Jessica K. Altman, Eunice S. Wang, Gail J. Roboz, Patrick W. Burke, Gianluca Gaidano, Roland B. Walter, Xavier Thomas, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Elisabetta Todisco, Kebede H. Begna, Anjali Advani, Lauris Gastaud, Adolfo De La Fuente, Antonio Curti, Lourdes M. Mendez, Paresh Vyas, Nicolas Boissel, Norbert Vey, Christian Recher, Thomas Longval, Uwe Platzbecker, Silke Kapp-Schwoerer, Christoph Schliemann, Marina Konopleva, Laura Torres, David A. Sallman, Guido Marcucci, Naveen Pemmaraju, Giovanni Martinelli, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Publikováno v:
Blood. 140:145-149
Autor:
Eunice S. Wang, Callum M. Sloss, Hagop M. Kantarjian, Lourdes M. Mendez, Lauris Gastaud, David A. Sallman, Kendra Sweet, Giovanni Martinelli, Xavier Thomas, Daniel J. DeAngelo, Christoph Schliemann, Naval Daver, Deepa Jeyakumar, Harry P. Erba, Roland B. Walter, Gail J. Roboz, Marina Konopleva, Jessica K. Altman, Gianluca Gaidano, Ahmed Aribi, Patrick W. Burke, Pau Montesinos, Guido Marcucci, Nicolas Boissel, Adolfo de la Fuente, Anjali S. Advani, Elisabetta Todisco, Kara E Malcolm, Laura Torres, Christian Recher, Antonio Curti, Patrick A. Zweidler-McKay
Publikováno v:
Blood. 138:372-372
BACKGROUND: Despite improvements in the treatment of "unfit or older" AML patients with the combination of azacitidine (AZA) and venetoclax (VEN), long-term survival for these patients remains poor. Additions to this new regimen may further improve p
Autor:
Andrew A. Lane, Ahmed Aribi, Hagop M. Kantarjian, Callum M. Sloss, Luca Mazzarella, Kara E Malcolm, Patrick A. Zweidler-McKay, Daniel J. DeAngelo, Roland B. Walter, Naval Daver, David A. Rizzieri, Eric Deconinck, Moshe Yair Levy, Elisabetta Todisco, Harry P. Erba, Evelyn Acuña-Cruz, Giovanni Martinelli, Delphine Lebon, Marina Konopleva, Giovanni Marconi, Naveen Pemmaraju, Eunice S. Wang, Kendra Sweet, Pau Montesinos, Federica Gigli
Publikováno v:
Blood. 138:1284-1284
BACKGROUND: BPDCN is a rare, aggressive hematologic malignancy characterized by historically poor overall survival and limited therapeutic options. Despite the recent approval of tagraxofusp-erzs for BPDCN, outcomes remain suboptimal for many patient
Autor:
Andrew A. Lane, Daniel J. DeAngelo, Ahmed Aribi, Naval Daver, Callum M. Sloss, Kendra Sweet, Eric Deconinck, Naveen Pemmaraju, Delphine Lebon, Hagop M. Kantarjian, David A. Rizzieri, J. Wang, Moshe Yair Levy, Federica Gigli, Pau Montesinos, Kara E Malcolm, Roland B. Walter, Harry P. Erba, Luca Mazzarella, Giovanni Martinelli, Evelyn Acuña-Cruz, Eunice S. Wang, Giovanni Marconi, Marina Konopleva, Elisabetta Todisco, Patrick A. Zweidler-McKay
Publikováno v:
Blood. 138:4429-4429
Background: Overexpression of CD123 (IL-3Rα receptor) is a hallmark of blastic plasmacytoid dendritic cell neoplasm (BPDCN), thus making this antigen an attractive target for the development of new therapeutics. IMGN632 is a CD123-targeting antibody
Autor:
Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Publikováno v:
Blood. 138:4440-4440
Background: Overexpression of CD123 is characteristic of a number of hematological malignancies, including acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm (BPDCN). IMGN632 is a CD123-targeting antibody-drug conjugate (AD
Autor:
Callum M. Sloss, Daniel J. DeAngelo, Ahmed Aribi, Jessica K. Altman, Kendra Sweet, Giovanni Martinelli, Pau Montesinos, Kara E Malcolm, Antonio Curti, Roland P Walter, Patrick A. Zweidler-McKay, Eunice S. Wang, Naval Daver, Harry P. Erba, Anjali S. Advani
Publikováno v:
Blood. 136:50-51
Background: IMGN632 is a CD123-targeting ADC, comprised of a high affinity anti-CD123 antibody coupled to a DNA-alkylating payload of the novel IGN (indolinobenzodiazepine pseudodimer) class. An ongoing Phase I trial in patients with CD123-positive A
Autor:
Naval Daver, Callum M. Sloss, Kendra Sweet, Eunice S. Wang, J. Wang, Patrick A. Zweidler-McKay, Harry P. Erba, Pau Montesinos, Daniel J. DeAngelo, Kara E Malcolm
Publikováno v:
Journal of Clinical Oncology. 38:TPS7564-TPS7564
TPS7564 Background: Overexpression of CD123 is characteristic of a number of hematological malignancies, including acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm (BPDCN). IMGN632 is a CD123-targeting antibody-drug conju
Autor:
Marina Konopleva, Roland B. Walter, Elisabetta Todisco, Callum M. Sloss, Naval Daver, Pau Montesinos, David A. Rizzieri, Corrado Tarella, Moshe Yair Levy, Kendra Sweet, Kara E Malcolm, Eunice S. Wang, Andrew A. Lane, J. Wang, Patrick A. Zweidler-McKay, Harry P. Erba, Daniel J. DeAngelo, Giovanni Martinelli, Eric Deconinck, Naveen Pemmaraju
Publikováno v:
Journal of Clinical Oncology. 38:TPS7563-TPS7563
TPS7563 Background: Overexpression of CD123 occurs in multiple hematological malignancies, including acute myeloid leukemia (AML), blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute lymphoblastic leukemia (ALL) and others, thus making this a
Autor:
Naval G. Daver, Harry P. Erba, Nikolaos Papadantonakis, Daniel J. DeAngelo, Eunice S. Wang, Marina Y Konopleva, Callum M. Sloss, Jiuzhou Wang, Kara E. Malcolm, Patrick A. Zweidler-McKay, Hagop M. Kantarjian
Publikováno v:
Blood. 134:2601-2601
Background: Overexpression of CD123, the alpha subunit of the IL-3 receptor, is characteristic of a number of hematological malignancies, including acute myeloid leukemia (AML), thus providing an attractive candidate for targeted therapeutic approach
Autor:
Naval Daver, Naveen Pemmaraju, Pau Montesinos, Kendra Sweet, Harry P. Erba, Giovanni Martinelli, J. Wang, Marina Konopleva, Eunice S. Wang, David A. Rizzieri, Andrew A. Lane, Hagop M. Kantarjian, Patrick A. Zweidler-McKay, Daniel J. DeAngelo, Corrado Tarella, Elisabetta Todisco, Kerry Culm-Merdek, Eric Deconinck, Kara E Malcolm, Nikolaos Papadantonakis, Callum M. Sloss
Publikováno v:
Blood. 134:1334-1334
Background: Overexpression of CD123, the alpha subunit of the IL-3 receptor, occurs in multiple hematological malignancies, including acute myeloid leukemia (AML), blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute lymphoblastic leukemia (AL