Výsledky vyhledávání - "Kara A, Furger"

The Functional and Clinical Roles of Osteopontin in Cancer and Metastasis

Autor: Ann F. Chambers, Kara A. Furger, Vivien H.C. Bramwell, Alan B. Tuck, Rajashree K. Menon

Publikováno v: Current Molecular Medicine. 1:621-632

Osteopontin (OPN) is a secreted and integrin-binding protein that has been implicated in a number of pathologies. In this review we will focus on the functional and clinical roles of OPN in cancer and metastasis, with a particular emphasis on breast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddf6c95308656a32af3fa51a41b97e8
https://doi.org/10.2174/1566524013363339

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Beta(3) integrin expression increases breast carcinoma cell responsiveness to the malignancy-enhancing effects of osteopontin

Autor: Kara A, Furger, Alison L, Allan, Sylvia M, Wilson, Charulata, Hota, Sharon A, Vantyghem, Carl O, Postenka, Waleed, Al-Katib, Ann F, Chambers, Alan B, Tuck

Publikováno v: Molecular cancer research : MCR. 1(11)

Osteopontin (OPN) is a secreted phosphoprotein that has been associated with malignancy of breast and other cancers. OPN binds to several cell surface integrins including alpha(v)beta(3), alpha(v)beta(5), and alpha(v)beta(1). Although the relative co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ff50a4ab1923a59e8a98c41579e7ebe
https://pubmed.ncbi.nlm.nih.gov/14517343

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