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Intramolecular Nitrene Insertion into Saturated C−H‐Bond‐Mediated C−N Bond Cleavage of a Coordinated NHC Ligand

Autor: Kar-Yee Lam, Chun-Wai Tse, Yungen Liu, Xiangguo Guan, Chi-Ming Che, Meng-Yao Chao, Xiaoyong Chang, Jie-Sheng Huang

Publikováno v: Chemistry – A European Journal. 25:10828-10833

Ruthenium(II) complexes bearing a tridentate bis(N-heterocyclic carbene) ligand reacted with iminoiodanes (PhI=NR) resulting in the formation of isolable ruthenium(III)-amido intermediates, which underwent cleavage of a C-N bond of the tridentate lig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4669b79ba7147d51d0349cc39088eb3d
https://doi.org/10.1002/chem.201903012

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A Macrocyclic Ruthenium(III) Complex Inhibits Angiogenesis with Down-Regulation of Vascular Endothelial Growth Factor Receptor-2 and Suppresses Tumor Growth In Vivo

Autor: Yau-Tsz Lai, PY Lee, Chun-Nam Lok, Wai-Lun Kwong, Kar-Yee Lam, Chi-Ming Che

Publikováno v: Angewandte Chemie. 128:13722-13726

A macrocyclic ruthenium(III) complex [RuIII(N2O2)Cl2]Cl (Ru-1) is reported as an inhibitor of angiogenesis and an anti-tumor compound. The complex is relatively non-cytotoxic towards endothelial and cancer cell lines in vitro, but specifically inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bcd44ce54ccc4bf85e0ebf4cf85fbed
https://doi.org/10.1002/ange.201608094

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Chiral iron pyridine complexes and ruthenium complexes with N-heterocyclic carbene and macrocyclic (N,O) donor atom ligands : synthesis, catalytic activity and biological studies

Autor: Kar-yee Lam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d1c54a7e5ba84b93634d031aebb525a
https://doi.org/10.5353/th_b5760936

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Laparoscopic sleeve gastrectomy with loop bipartition: A novel metabolic operation in treating obese type II diabetes mellitus

Autor: Katherine Kar-Yee Lam, Wilfred Lik-Man Mui, Danny Wai-Hung Lee

Publikováno v: International Journal of Surgery Case Reports

INTRODUCTION We report the first case of laparoscopic sleeve gastrectomy with loop bipartition (a modified form of Santoro's operation) in the treatment of type II diabetes mellitus associated with obesity. PRESENTATION OF CASE A 46-year-old gentlema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ec7b028405b7753907deb52af0d72b
https://doi.org/10.1016/j.ijscr.2013.12.002

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Silica-Supported Gold Nanoparticles Catalyzed One-Pot, Tandem Aerobic Oxidative Cyclization Reaction for Nitrogen-Containing Polyheterocyclic Compounds

Autor: Chi-Ming Che, Kar-Yee Lam, Yungen Liu, Man-Ho So, Chi-Ming Ho

Publikováno v: ChemCatChem. 3:386-393

A silica-supported gold nanoparticle catalyst AuNPs/SiO2 (A) has been prepared by deposition of in situ synthesized gold nanoparticles (AuNPs) onto the surface of silica. A simple method that uses A as the catalyst and oxygen as the oxidant is effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a1cf6339c684fcbb946bc835998bb4e3
https://doi.org/10.1002/cctc.201000312

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Expression of EEN (endophilin II) : a fusion partner gene in leukemia, in haemopoietic cells

Autor: Kar-yee. Lam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c566259d6a269bf44aebce512f64cfe6
https://doi.org/10.5353/th_b3122617

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ChemInform Abstract: Silica-Supported Gold Nanoparticles Catalyzed One-Pot, Tandem Aerobic Oxidative Cyclization Reaction for Nitrogen-Containing Polyheterocyclic Compounds

Autor: Chi-Ming Che, Kar-Yee Lam, Yungen Liu, Man-Ho So, Chi-Ming Ho

Publikováno v: ChemInform. 42

The catalyst can be easily recovered by centrifugation and reused for seven consecutive runs without significant loss of activity.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::25f871220761935ebe018e49c34bc740
https://doi.org/10.1002/chin.201122154

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Normalization of renal aquaporin-2 water channel expression by fosinopril, valsartan, and combination therapy in congestive heart failure: a new mechanism of action

Autor: Joseph Leung, Kar-Yee Lam, Kevin Lai, Cheuk-Man Yu, Kar-Neng Lai, Pik-Shan Li

Publikováno v: Journal of molecular and cellular cardiology. 36(3)

This study investigated the effect of fosinopril (Fos), valsartan (Val), and combination of both drugs (Fos + Val) on the cardiac and renal expression of aquaporin-1 (AQP1) and aquaporin-2 (AQP2) in congestive heart failure (CHF). A rat model of CHF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3173c90abdfe91adc871000985d3c97b
https://pubmed.ncbi.nlm.nih.gov/15010283

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