Zobrazeno 1 - 10
of 712
pro vyhledávání: '"Kar-Neng Lai"'
Autor:
Bin Li, Joseph C.K. Leung, Loretta Y.Y. Chan, Hong-Yu Li, Wai-Han Yiu, Sarah W.Y. Lok, Rui Xue, Yi-Xin Zou, Wei Chen, Kar-Neng Lai, Sydney C.W. Tang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1280-1290 (2021)
Lipotoxicity has been implicated in the pathogenesis of obesity-related kidney damage and propagates chronic kidney injury like diabetic kidney disease; however, the underlying mechanisms have not yet been fully elucidated. To date, reduction of lipi
Externí odkaz:
https://doaj.org/article/6d11bacee341458d8eb557cbe41483d8
Autor:
Kam Wa Chan, Kam Yan Yu, Wai Han Yiu, Rui Xue, Sarah Wing-yan Lok, Hongyu Li, Yixin Zou, Jinyuan Ma, Kar Neng Lai, Sydney Chi-wai Tang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Previous retrospective cohorts showed that Rehmannia-6 (R-6, Liu-wei-di-huang-wan) formulations were associated with significant kidney function preservation and mortality reduction among chronic kidney disease patients with diabetes. Thi
Externí odkaz:
https://doaj.org/article/fb2d86443ef848dfa3015cc6fda0e6b3
Autor:
Kam Wa Chan, Pak Wing Lee, Crystal Pui Sha Leung, Gary Chi Wang Chan, Wai Han Yiu, Hoi Man Cheung, Bin Li, Sarah Wing Yan Lok, Hongyu Li, Rui Xue, Loretta Yuk Yee Chan, Joseph Chi Kam Leung, Tai Pong Lam, Kar Neng Lai, Sydney Chi Wai Tang
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Difference of perspective between patients and physicians over integrative medicine (IM) research and service provision remains unclear despite significant use worldwide. We observed an exceptionally low utilisation of IM and pote
Externí odkaz:
https://doaj.org/article/a98e389eb7fd4bbc9ae9e5edff02c171
Autor:
Kar Neng Lai
This manual provides practical and accessible information on all aspects of general nephrology, dialysis, and transplantation. It outlines current therapies in straightforward language to help readers understand the treatment rationale, and does not
Autor:
Kar Neng Lai
IgA nephropathy is the most common primary glomerulonephritis in developed countries. The primary defect lies in the abnormalities of the IgA molecule. The disease affects all ages, mainly in the young adults, and may recur in a transplanted kidney.T
Autor:
Wai Han Yiu, Sarah W.Y. Lok, Rui Xue, Jiaoyi Chen, Kar Neng Lai, Hui Yao Lan, Sydney C.W. Tang
Publikováno v:
Clinical Science. 137:317-331
Kidney inflammation contributes to the progression of chronic kidney disease (CKD). Modulation of Toll-like receptor 4 (TLR4) signaling is a potential therapeutic strategy for this pathology, but the regulatory mechanisms of TLR4 signaling in kidney
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a30d6abef74fdf65fab89ee4331afca
https://doi.org/10.1042/cs20220537
https://doi.org/10.1042/cs20220537
Autor:
Davina N. W. Lie, Kam Wa Chan, Alexander H. N. Tang, Anthony T. P. Chan, Gary C. W. Chan, Kar Neng Lai, Sydney Chi-Wai Tang
Publikováno v:
Journal of Nephrology. 36:407-416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73eb5f6e1f1ca802de04722960cae1b1
https://doi.org/10.1007/s40620-022-01530-7
https://doi.org/10.1007/s40620-022-01530-7
Autor:
Sarah W Y Lok, Wai Han Yiu, Yixin Zou, Rui Xue, Hongyu Li, Jingyuan Ma, Jiaoyi Chen, Loretta Y Y Chan, Kar Neng Lai, Sydney C W Tang
Publikováno v:
Nephrology Dialysis Transplantation.
Background Thromboembolic events are prevalent in chronic kidney disease (CKD) patients due to increased thrombin generation leading to a hypercoagulable state. We previously demonstrated that inhibition of protease-activated receptor-1 (PAR-1) by vo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e0d66187142cc9a912265febfa8299
https://doi.org/10.1093/ndt/gfad051
https://doi.org/10.1093/ndt/gfad051
Autor:
Hongyu Li, Joseph C. K. Leung, Wai Han Yiu, Loretta Y. Y. Chan, Bin Li, Sarah W. Y. Lok, Rui Xue, Yixin Zou, Kar Neng Lai, Sydney C. W. Tang
Publikováno v:
Cell Death & Disease. 13
Mitochondria take part in a network of intracellular processes that regulate homeostasis. Defects in mitochondrial function are key pathophysiological changes during AKI. Although Wnt/β-catenin signaling mediates mitochondrial dysfunction in chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed50c68a26a99447075a74a1e610ed9
https://doi.org/10.1038/s41419-022-05395-3
https://doi.org/10.1038/s41419-022-05395-3
Autor:
Yi-Xin Zou, Sydney C.W. Tang, Loretta Y.Y. Chan, Joseph Leung, Hongyu Li, Rui Xue, Kar-Neng Lai, Wai-Han Yiu, Bin Li, Sarah W.Y. Lok, Wei Chen
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 1280-1290 (2021)
Molecular Therapy: Nucleic Acids, Vol 26, Iss, Pp 1280-1290 (2021)
Lipotoxicity has been implicated in the pathogenesis of obesity-related kidney damage and propagates chronic kidney injury like diabetic kidney disease; however, the underlying mechanisms have not yet been fully elucidated. To date, reduction of lipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0931da0b22d06f7cb5cb122fcbbcb64f
http://europepmc.org/articles/PMC8609107
http://europepmc.org/articles/PMC8609107