Zobrazeno 1 - 10
of 712
pro vyhledávání: '"Kar Neng, Lai"'
Autor:
Hongyu Li, Joseph C. K. Leung, Wai Han Yiu, Loretta Y. Y. Chan, Bin Li, Sarah W. Y. Lok, Rui Xue, Yixin Zou, Kar Neng Lai, Sydney C. W. Tang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-15 (2022)
Abstract Mitochondria take part in a network of intracellular processes that regulate homeostasis. Defects in mitochondrial function are key pathophysiological changes during AKI. Although Wnt/β-catenin signaling mediates mitochondrial dysfunction i
Externí odkaz:
https://doaj.org/article/82f9885eca8b4c88bf8be3fca5551bed
Autor:
Bin Li, Joseph C.K. Leung, Loretta Y.Y. Chan, Hong-Yu Li, Wai-Han Yiu, Sarah W.Y. Lok, Rui Xue, Yi-Xin Zou, Wei Chen, Kar-Neng Lai, Sydney C.W. Tang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1280-1290 (2021)
Lipotoxicity has been implicated in the pathogenesis of obesity-related kidney damage and propagates chronic kidney injury like diabetic kidney disease; however, the underlying mechanisms have not yet been fully elucidated. To date, reduction of lipi
Externí odkaz:
https://doaj.org/article/6d11bacee341458d8eb557cbe41483d8
Autor:
Kam Wa Chan, Kam Yan Yu, Wai Han Yiu, Rui Xue, Sarah Wing-yan Lok, Hongyu Li, Yixin Zou, Jinyuan Ma, Kar Neng Lai, Sydney Chi-wai Tang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Previous retrospective cohorts showed that Rehmannia-6 (R-6, Liu-wei-di-huang-wan) formulations were associated with significant kidney function preservation and mortality reduction among chronic kidney disease patients with diabetes. Thi
Externí odkaz:
https://doaj.org/article/fb2d86443ef848dfa3015cc6fda0e6b3
Autor:
Kam Wa Chan, Pak Wing Lee, Crystal Pui Sha Leung, Gary Chi Wang Chan, Wai Han Yiu, Hoi Man Cheung, Bin Li, Sarah Wing Yan Lok, Hongyu Li, Rui Xue, Loretta Yuk Yee Chan, Joseph Chi Kam Leung, Tai Pong Lam, Kar Neng Lai, Sydney Chi Wai Tang
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Difference of perspective between patients and physicians over integrative medicine (IM) research and service provision remains unclear despite significant use worldwide. We observed an exceptionally low utilisation of IM and pote
Externí odkaz:
https://doaj.org/article/a98e389eb7fd4bbc9ae9e5edff02c171
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Introduction: The quantitative effect of underlying non-communicable diseases on acute kidney injury (AKI) incidence and the factors affecting the odds of death among coronavirus disease 2019 (COVID-19) AKI patients were unclear at population level.
Externí odkaz:
https://doaj.org/article/56b325ded9de4db9b53b32e0e7862d12
Autor:
Kar Neng Lai
This manual provides practical and accessible information on all aspects of general nephrology, dialysis, and transplantation. It outlines current therapies in straightforward language to help readers understand the treatment rationale, and does not
Autor:
Kar Neng Lai
IgA nephropathy is the most common primary glomerulonephritis in developed countries. The primary defect lies in the abnormalities of the IgA molecule. The disease affects all ages, mainly in the young adults, and may recur in a transplanted kidney.T
Autor:
Bin Li, Joseph C. K. Leung, Loretta Y. Y. Chan, Wai Han Yiu, Ye Li, Sarah W. Y. Lok, Wing Han Liu, Kam Wa Chan, Hung Fat Tse, Kar Neng Lai, Sydney C. W. Tang
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 9, Pp 898-910 (2019)
Abstract Recent advances in the understanding of lipid metabolism suggest a critical role of endoplasmic reticulum (ER) stress in obesity‐induced kidney injury. Hepatocyte growth factor (HGF) is a pleiotropic cytokine frequently featured in stem ce
Externí odkaz:
https://doaj.org/article/a453fdba754f45889e9cc16ac51176ae
Autor:
Wai Han Yiu, Sarah W.Y. Lok, Rui Xue, Jiaoyi Chen, Kar Neng Lai, Hui Yao Lan, Sydney C.W. Tang
Publikováno v:
Clinical Science. 137:317-331
Kidney inflammation contributes to the progression of chronic kidney disease (CKD). Modulation of Toll-like receptor 4 (TLR4) signaling is a potential therapeutic strategy for this pathology, but the regulatory mechanisms of TLR4 signaling in kidney
Autor:
Wai Han Yiu, Kam Wa Chan, Loretta Y. Y. Chan, Joseph C. K. Leung, Kar Neng Lai, Sydney C. W. Tang
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase involved in signal transduction in a variety of immune responses. It has been demonstrated that Syk plays a pathogenic role in orchestrating inflammatory responses and cell proliferation
Externí odkaz:
https://doaj.org/article/a4a3de2399374b749e791af0560293a5