Výsledky vyhledávání - "Kapur B. Dhami"

Development of a Simple and Effective Lipid-A Antagonist Based on Computational Prediction

Autor: Olivia Slater, Kapur B. Dhami, Ganesh Shrestha, Maria Kontoyianni, Michael R. Nichols, Alexei V. Demchenko

Publikováno v: ACS Infect Dis

Sepsis is a serious medical condition characterized by bacterial infection and a subsequent massive systemic inflammatory response. In an effort to identify compounds that block lipopolysaccharide (LPS)-induced inflammation reported herein is the dev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850fe349441a73af2495ff7a9bd060f8
https://europepmc.org/articles/PMC9402072/

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Effect of mesoporous silica nanoparticles loaded with α-tomatine on HepG2 cancer cells studied in vitro

Autor: Bishal Nepal, Jay K. Bhattarai, Kapur B. Dhami, Michael R. Nichols, Keith J. Stine

Publikováno v: Journal of Drug Delivery Science and Technology. 79:104033

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::603d1520f8ca4cd463a63a9bc24230f9
https://doi.org/10.1016/j.jddst.2022.104033

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Development of β-sheet structure in Aβ aggregation intermediates diminishes exposed hydrophobic surface area and enhances proinflammatory activity

Autor: Kapur B. Dhami, Sanjib Karki, Antanisha Parks, Cameron G. Nichols, Michael R. Nichols

Publikováno v: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1870:140817

Three decades of research, both in vitro and in vivo, have demonstrated the conformational heterogeneity that is displayed by the amyloid β peptide (Aβ) in Alzheimer's disease (AD). Understanding the distinct properties between Aβ conformations an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052971597fe464a3be5057a9a579d615
https://doi.org/10.1016/j.bbapap.2022.140817

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