Protocol for a randomised, multicentre, four-arm, double-blinded, placebo-controlled trial to assess the benefits and safety of iron supplementation with malaria chemoprevention to children in Malawi: IRMA trial.

Autor: Mwangi MN; Training and Research Unit of Excellence (TRUE), Blantyre, Malawi mmwangi@true.mw.; The Micronutrient Forum, Healthy Mothers Healthy Babies Consortium, Washington DC, Washington, USA., Mzembe G; Training and Research Unit of Excellence (TRUE), Blantyre, Malawi.; Department of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Ngwira CC; Training and Research Unit of Excellence (TRUE), Blantyre, Malawi., Vokhiwa M; Training and Research Unit of Excellence (TRUE), Blantyre, Malawi.; Department of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Kapulula MD; Training and Research Unit of Excellence (TRUE), Blantyre, Malawi., Larson LM; Department of Health Promotion, Education, and Behaviour, University of South Carolina Arnold School of Public Health, Columbia, South Carolina, USA., Braat S; Department of Infectious Diseases at the Peter Doherty Institute of Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.; Centre for Epidemiology and Biostatistics, University of Melbourne School of Population and Global Health, Carlton, Victoria, Australia.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Harding R; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., McLean ARD; Centre for Epidemiology and Biostatistics, University of Melbourne School of Population and Global Health, Carlton, Victoria, Australia.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Hamadani JD; International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh., Biggs BA; Department of Infectious Diseases at the Peter Doherty Institute of Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.; Diagnostic Haematology, The Royal Melbourne Hospital; and Clinical Haematology, Melbourne, Victoria, Australia., Ataíde R; Department of Infectious Diseases at the Peter Doherty Institute of Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Phiri KS; Training and Research Unit of Excellence (TRUE), Blantyre, Malawi.; Department of Public Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Pasricha SR; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Diagnostic Haematology, The Royal Melbourne Hospital; and Clinical Haematology, Melbourne, Victoria, Australia.; Department of Medical Biology, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.

Publikováno v: BMJ open [BMJ Open] 2023 Oct 13; Vol. 13 (10), pp. e069011. Date of Electronic Publication: 2023 Oct 13.