Synthesis of 1-alkyl-2,3-dihydro-2-(4-pyridinyl)-1 H-isoindoles as potential selective serotonin reuptake inhibitors.

Autor: Kapples, Kevin J., Shutske, Gregory M.

Publikováno v: Journal of Heterocyclic Chemistry; Jul1997, Vol. 34 Issue 4, p1335-1338, 4p

Synthesis of novel pyrido[3,4- f]pyrrolo[1,2- b][1,2,5]triazepines. A Novel heterocyclic ring system.

Autor: Effland, Richard C., Davis, Larry, Kapples, Kevin J., Olsen, Gordon E.

Publikováno v: Journal of Heterocyclic Chemistry; May1990, Vol. 27 Issue 4, p1015-1019, 5p

Aminopyridine Carbamic Acid Esters: Synthesis and Potential as Acetylcholinesterase Inhibitors and Acetylcholine Releasers

Autor: Shutske, Gregory M., Tomer, John D., Kapples, Kevin J., Hrib, Nicholas J., Jurcak, John G., Bores, Gina M., Huger, Francis P., Petko, Wayne, Smith, Craig P.

Publikováno v: Journal of Pharmaceutical Sciences; April 1992, Vol. 81 Issue: 4 p380-385, 6p

Synthesis and biological activity of putative mono-hydroxylated metabolites of velnacrine

Autor: Shutske, Gregory M., Bores, Gina M., Bradshaw, Katherine C., Huger, Francis P., Kapples, Kevin J., Larsen, Raymond D., Rush, Douglas K., Tomer, John D.

Publikováno v: In Bioorganic & Medicinal Chemistry Letters 1992 2(8):865-870

Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.

Autor: Hendrix JA; Aventis Pharmaceuticals Route, 202-206, PO Box 6800, Bridgewater, NJ 08807-0800, USA. james.hendrix@aventis.com, Shimshock SJ, Shutske GM, Tomer JD 4th, Kapples KJ, Palermo MG, Corbett TJ, Vargas HM, Kafka S, Brooks KM, Laws-Ricker L, Lee DK, de Lannoy I, Bordeleau M, Rizkalla G, Owolabi J, Kamboj RK

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2002 Oct 04; Vol. 3 (10), pp. 999-1009.