The development of HPLC-DAD method for determination of active pharmaceutical ingredient in the potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio) acetate substance

Autor: Shcherbyna Roman, Parchenko Volodymyr, Varynskyi Boris, Kaplaushenko Andriy

Publikováno v: Current Issues in Pharmacy and Medical Sciences, Vol 32, Iss 1, Pp 5-9 (2019)

Derivatives of 1,2,4-triazole are actively researched by scientists and synthetic pharmacologists. The last studies have shown that potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio)acetate with low toxicity series exhibits antiox

Externí odkaz: https://doaj.org/article/de330a60157e4878b5e6031eba97b795

Синтез та дослідження фізико-хімічних властивостей похідних 1,2,4-триазолу, що містять фенетильний замісник у положенні 5

Autor: Ihnatova, Tetiana V., Kaplaushenko, Andriy G., Frolova, Yuliia S.

Publikováno v: Журнал органічної та фармацевтичної хімії; Том 18, № 2(70) (2020); 48-53
Journal of Organic and Pharmaceutical Chemistry; Том 18, № 2(70) (2020); 48-53
Журнал органической и фармацевтической химии; Том 18, № 2(70) (2020); 48-53

During the last decade, national and foreign scientists have been constantly examining an example of studying the physicochemical and biological properties of nitrogen containing heterocycles, particularly with the nucleus of 1,2,4-triazole. The main

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=scientific_p::30573cf6a2e2c7bb7491d3ee0e17c943
http://ophcj.nuph.edu.ua/article/view/ophcj.20.175671

Synthesis and antioxidant properties of new (2,4- and 3,4-dimethoxyphenyl)-1,2,4-triazoles.

Autor: Dovbnya, Dmitro V., Kaplaushenko, Andriy H., Frolova, Yuliia S., Pruglo, Evheniy S.

Publikováno v: Pharmacia (0428-0296); 2022, Vol. 69 Issue 1, p135-142, 8p

Tryfuzol - New original veterinary drug

Autor: BUSHUEVA, Inna, PARCHENKO, Volodymyr, SHCHERBYNA, Roman, SAFONOV, Andriy, KAPLAUSHENKO, Andriy, GUTYJ, Bogdan, HARIV, Ivan

Publikováno v: Volume: 41, Issue: 1
Journal of Faculty of Pharmacy of Ankara University

Bilimsel ekibimiz, son yıllardaki incelediği bilimsel yayımlar sonucunda furan ile sübstitüe 1,2,4- triazollerin düşük toksisitesi ve çeşitli aktivitelerinden dolayı gelecek çalışmalar için umut verici olduğunu bulmuştur. Ukrayna’d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=tubitakulakb::6489e5c5f7392c808f476ad87d1cfcfd
https://dergipark.org.tr/tr/pub/jfpanu/issue/35473/394042

ELECTROSPRAY IONIZATION MASS SPECTROMETRY FRAGMENTATION PATHWAYS OF SALTS OF SOME 1,2,4-TRIAZOLYLTHIOACETATE ACIDS, THE ACTIVE PHARMACEUTICAL INGREDIENTS

Autor: Varynskyi Borys, Kaplaushenko Andriy, Parchenko Vladymyr

Publikováno v: Asian Journal of Pharmaceutical and Clinical Research. 11:303

Objective: The goal of this research was to study fragmentation pathways of series salts of 1,2,4-triazolylthioacetate acids. Methods: The study was done in the Electrospray ionization source with single quadrupole mass spectrometer Agilent 6120 afte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::436eb5978e8c3095d5de46ef23651254
https://doi.org/10.22159/ajpcr.2018.v11i10.16564