Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kapish Gupta"'
Autor:
Kapish Gupta, Jimmy P Xu, Tamir Diamond, Iris E M de Jong, Andrew Glass, Jessica Llewellyn, Neil D Theise, Orith Waisbourd-Zinman, Jeffrey D Winkler, Edward M Behrens, Clementina Mesaros, Rebecca G Wells
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301824 (2024)
Biliary atresia is a neonatal disease characterized by damage, inflammation, and fibrosis of the liver and bile ducts and by abnormal bile metabolism. It likely results from a prenatal environmental exposure that spares the mother and affects the fet
Externí odkaz:
https://doaj.org/article/74507efcbeca4a1daf62e83fff6e33fb
Autor:
Alec O’Keeffe, Christine Hale, James A. Cotton, Vanessa Yardley, Kapish Gupta, Abhishek Ananthanarayanan, Sudaxshina Murdan, Simon L. Croft
Publikováno v:
Microorganisms, Vol 8, Iss 6, p 831 (2020)
The discovery of novel anti-leishmanial compounds remains essential as current treatments have known limitations and there are insufficient novel compounds in development. We have investigated three complex and physiologically relevant in vitro assay
Externí odkaz:
https://doaj.org/article/d2fc0f3ef4dc41758400f1ead02e723e
Autor:
Kapish Gupta
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology.
Hepatocytes produce bile components and secrete them into a lumen, known as a bile canaliculus, that is formed by the apical membranes of adjoining hepatocytes. Bile canaliculi merge to form tubular structures that subsequently connect to the canal o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8966348b5639cd3cbe0180676bc14bb3
https://doi.org/10.1152/ajpgi.00165.2022
https://doi.org/10.1152/ajpgi.00165.2022
Autor:
Kapish Gupta, Jimmy P. Xu, Tamir Diamond, Iris De Jong, Andrew Glass, Jessica Llewellyn, Neil D. Theise, Jeffrey D. Winkler, Edward M. Behrens, Clementina Mesaros, Rebecca G. Wells
Background & AimsBiliary atresia is a neonatal disease characterized by bile duct and liver damage, fibrosis, inflammation and abnormal bile metabolism. It appears to result from a prenatal exposure that spares the mother and affects the fetus. Our a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645ec5fd81d29f6607add99a95ae9e63
https://doi.org/10.1101/2023.03.02.530913
https://doi.org/10.1101/2023.03.02.530913
Autor:
Yu Du, Kapish Gupta, Orith Waisbourd-Zinman, Adi Har-Zahav, Carol J. Soroka, James L. Boyer, Jessica Llewellyn, Chengyang Liu, Ali Naji, William J. Polacheck, Rebecca G. Wells
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease in which the bile ducts of the liver become inflamed and scarred. Scarred bile ducts eventually narrow and obstruct and can cause additional liver pathology including liver f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7eef1236aff159191bd79bb02fe9291
https://doi.org/10.1101/2023.03.02.530888
https://doi.org/10.1101/2023.03.02.530888
Autor:
Iris E.M. de Jong, Mallory L. Hunt, Dongning Chen, Yu Du, Jessica Llewellyn, Kapish Gupta, Dorothea Erxleben, Felipe Rivas, Adam R. Hall, Emma E. Furth, Ali Naji, Chengyang Liu, Abhishek Dhand, Jason Burdick, Marcus G. Davey, Alan W. Flake, Robert J. Porte, Pierre A. Russo, J. William Gaynor, Rebecca G. Wells
IntroductionBiliary atresia (BA) is an obstructive cholangiopathy that initially affects the extrahepatic bile ducts (EHBDs) of neonates. The etiology is uncertain, but evidence points to a prenatal cause; however, the response of the fetal EHBD to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::272df5e6ba1a178955de99f3f74a99e8
https://doi.org/10.1101/2022.12.15.520656
https://doi.org/10.1101/2022.12.15.520656
Autor:
Iris de Jong, Mallory Hunt, Kapish Gupta, Yu Du, Jessica Llewellyn, Abhishek Dhand, Robert Porte, William Gaynor, Rebecca Wells
Publikováno v:
Journal of Hepatology. 77:S740
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::194f04c1dc71b39c427b4ebe05a57ddb
https://doi.org/10.1016/s0168-8278(22)01800-1
https://doi.org/10.1016/s0168-8278(22)01800-1
Autor:
Zhihua Li, Zijian Chen, Yanan Gao, Yi Xing, Yuping Zhou, Yucheng Luo, Weihong Xu, Zhengchang Chen, Xu Gao, Kapish Gupta, Karthic Anbalakan, Lei Chen, Chuang Liu, Jian Kong, Hwa Liang Leo, Chengzhi Hu, Hanry Yu, Qiongyu Guo
Publikováno v:
Biomaterials. 283:121426
Transcatheter medical micro-devices through circulatory system show great potential for therapy but lack strategies to stably anchor them at the desired site in vascularized tissues to take actions. Here a shape memory functionalized biodegradable ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd6f58b232f41623e6a00cc0eab4e4f
https://doi.org/10.1016/j.biomaterials.2022.121426
https://doi.org/10.1016/j.biomaterials.2022.121426
Autor:
Sudaxshina Murdan, Simon L. Croft, Kapish Gupta, Alec O'Keeffe, Christine Hale, Vanessa Yardley, James Cotton, Abhishek Ananthanarayanan
Publikováno v:
Microorganisms
Volume 8
Issue 6
Microorganisms, Vol 8, Iss 831, p 831 (2020)
Volume 8
Issue 6
Microorganisms, Vol 8, Iss 831, p 831 (2020)
The discovery of novel anti-leishmanial compounds remains essential as current treatments have known limitations and there are insufficient novel compounds in development. We have investigated three complex and physiologically relevant in vitro assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dda562efbd1a1d8cae8491e192e9af3
Autor:
Aimin Li, Zenan Wang, Lei Xia, Xiaobei Luo, Abhishek Ananthanarayanan, Side Liu, Hanry Yu, Rashidah Binte Sakban, Kapish Gupta
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports
Scientific Reports
Shortage of functional hepatocytes hampers drug safety testing and therapeutic applications because mature hepatocytes cannot be expanded and maintain functions in vitro. Recent studies have reported that liver progenitor cells can originate from mat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb021e5f8ff3aa63acaac81e07bf469b
http://link.springer.com/article/10.1038/s41598-018-20304-5
http://link.springer.com/article/10.1038/s41598-018-20304-5