Design and Synthesis of Various Aryl Amide Derivatives of Imidazo[1,5-a] Pyridine-1,2,4-Thiadiazoles: In Vitro Cytotoxicity Evaluation and In Silico Molecular Docking Studies.

Autor: Ghanta S; Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar, Andhra Pradesh, India., Chandrasekhar C; Department of Chemistry, University College of Engineering (Autonomous), Jawaharlal Nehru Technological University, Kakinada, Andhra Pradesh, India., Sravani D; Department of Humanities & Basic Sciences, Aditya College of Engineering & Technology, Surampalem, Andhra Pradesh, India., Tej MB; Department of Healthcare Informatics, Sacred Heart University, Fair Fields, Connecticut, USA., Syed T; Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha, Saudi Arabia., Kapavarapu RK; Department of Pharmaceutical Chemistry and Phytochemistry, Nirmala College of Pharmacy, Mangalagiri, Andhra Pradesh, India., Raju RR; Department of Chemistry, Acharya Nagarjuna University, Nagarjuna Nagar, Andhra Pradesh, India.

Publikováno v: Chemistry & biodiversity [Chem Biodivers] 2024 Nov 18, pp. e202401380. Date of Electronic Publication: 2024 Nov 18.

InCl 3 mediated heteroarylation of indoles and their derivatization via CH activation strategy: Discovery of 2-(1H-indol-3-yl)-quinoxaline derivatives as a new class of PDE4B selective inhibitors for arthritis and/or multiple sclerosis.

Autor: Sunke R; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Bankala R; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Thirupataiah B; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, 576 104, Karnataka, India., Ramarao EVVS; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Kumar JS; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Doss HM; Immunopathology Lab, School of BioSciences and Technology, VIT University, Vellore, 632014, India., Medishetti R; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Kulkarni P; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Kapavarapu RK; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India., Rasool M; Immunopathology Lab, School of BioSciences and Technology, VIT University, Vellore, 632014, India., Mudgal J; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, 576 104, Karnataka, India., Mathew JE; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, 576 104, Karnataka, India., Shenoy GG; Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Madhav Nagar, 576 104, Karnataka, India., Parsa KVL; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India. Electronic address: KishoreP@DRILS.ORG., Pal M; Immunopathology Lab, School of BioSciences and Technology, VIT University, Vellore, 632014, India. Electronic address: manojitpal@rediffmail.com.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2019 Jul 15; Vol. 174, pp. 198-215. Date of Electronic Publication: 2019 Apr 16.