Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Kaoxiang Sun"'
Autor:
Wenyan Wang, Xiaofeng Wang, Ying Dong, David P. Walling, Pinglan Liu, Wanhui Liu, Yanan Shi, Kaoxiang Sun
Publikováno v:
Neurology and Therapy, Vol 13, Iss 2, Pp 355-372 (2024)
Abstract Introduction RYKINDO® (Rykindo) is a novel, long-acting injectable risperidone formulation administered biweekly (Q2W) through intramuscular gluteal injection for the treatment of schizophrenia in adult patients. This analysis was conducted
Externí odkaz:
https://doaj.org/article/eb5a4c92c10c427c9cebda73cdd8fb85
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractTriptorelin is a first-line drug for assisted reproductive technology (ART), but the low bioavailability and frequent subcutaneous injection of triptorelin impair the quality of life of women preparing to become pregnant. We report silk fibro
Externí odkaz:
https://doaj.org/article/e92cbe4a481b42f49475f94ddacae8b0
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractDoxorubicin (DOX) is a commonly studied chemotherapeutic agent for the treatment of solid tumors, but the severe side effects limit its clinical application. It is shown that DOX-metal chelate has lower in vitro cytotoxicity compared with DOX
Externí odkaz:
https://doaj.org/article/83ea033f1db540cb9c49649dcf77e60f
Autor:
Tianyu Zhang, Nuannuan Li, Ru Wang, Yiying Sun, Xiaoyan He, Xiaoyan Lu, Liuxiang Chu, Kaoxiang Sun
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractDoxorubicin (DOX), a commonly used anti-cancer drug, is limited by its cardiotoxicity and multidrug resistance (MDR) of tumor cells. Epigallocatechin gallate (EGCG), a natural antioxidant component, can effectively reduce the cardiotoxicity o
Externí odkaz:
https://doaj.org/article/03145bf4157f4b49a8c3258f69c1f6ec
Autor:
Jibiao He, Ruihuan Ding, Yuping Tao, Zhenyu Zhao, Ranran Yuan, Houqian Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractThe oral absorption of exenatide, a type 2 diabetes medication, can be increased by employing lipid nanocapsules (LNC). To increase mucus permeability and exenatide intestinal absorption, reverse micelle lipid nanocapsules (RM-LNC) were prepa
Externí odkaz:
https://doaj.org/article/01af0ca650e54fb5b133f6bdf4c70e57
Autor:
Ru Wang, Nuannuan Li, Tianyu Zhang, Yiying Sun, Xiaoyan He, Xiaoyan Lu, Liuxiang Chu, Kaoxiang Sun
Publikováno v:
Drug Delivery, Vol 30, Iss 1 (2023)
AbstractMitoxantrone (MX) can induce the immunogenic-cell death (ICD) of tumor cells and activate anti-tumor immune responses. However, it can also cause high expression of indole amine 2, 3-dioxygenase (IDO) during ICD, leading to T-cell apoptosis a
Externí odkaz:
https://doaj.org/article/2fb7697ded2b4d45b98cd7482ceb1b6d
Autor:
Yanzi Liang, Ruihuan Ding, Huihui Wang, Lanze Liu, Jibiao He, Yuping Tao, Zhenyu Zhao, Jie Zhang, Aiping Wang, Kaoxiang Sun, Youxin Li, Yanan Shi
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 305-315 (2022)
Oral drug delivery to treat diabetes is being increasingly researched. The mucus and the epithelial cell layers hinder drug delivery. We designed a self-ablating nanoparticle to achieve smart oral delivery to overcome the gastrointestinal barrier. We
Externí odkaz:
https://doaj.org/article/9558765b16e14ea6a28354b8dcaa8ab5
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 574-587 (2022)
A novel hyaluronic acid (HA)-modified hybrid nanocomplex HA-SeSe-COOH/siR-93C@PAMAM, which could efficiently deliver siRNA into tumor cells via a redox-mediated intracellular disassembly, was constructed for enhanced antitumor efficacy. Thereinto, si
Externí odkaz:
https://doaj.org/article/626934ea5a084af5b2cb8f23d4579379
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/ab46e323c20747e3ae92ba921b327af7
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-27 (2022)
Abstract Surface charge of biological and medical nanocarriers has been demonstrated to play an important role in cellular uptake. Owing to the unique physicochemical properties, charge-reversal delivery strategy has rapidly developed as a promising
Externí odkaz:
https://doaj.org/article/864e383f097c48b6bb942f23371fe79a