Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kaoru Terai"'
Autor:
Eun K. Choi, Kaoru Terai, In-Mi Ji, Yeon H. Kook, Kyung H. Park, Eun T. Oh, Robert J. Griffin, Byung U. Lim, Jin-Seok Kim, Doo S. Lee, David A. Boothman, Melissa Loren, Chang W. Song, Heon Joo Park
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 8, Pp 634-642 (2007)
We found that (β-Lapachone ((β-Lap), a novel bioreductive drug, caused rapid apoptosis, clonogenic cell death in A549 human lung epithelial cancer cells in vitro in a dose-dependent manner. The clonogenic cell death caused by (β-Lap could be signi
Externí odkaz:
https://doaj.org/article/d5fb5abdfc0140cea846617cc3fda72d
Autor:
Albert C Sek, Zhihui Xie, Kaoru Terai, Lauren M Long, Celeste Nelson, Arkadiusz Z Dudek, Kirk M Druey
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133266 (2015)
Idiopathic systemic capillary leak syndrome (SCLS) is a rare and potentially fatal vascular disorder characterized by reversible bouts of hypotension and edema resulting from fluid and solute escape into soft tissues. Although spikes in permeability-
Externí odkaz:
https://doaj.org/article/3e179512b00a4ccbab14894d4edda239
Correction: Endothelial Expression of Endothelin Receptor A in the Systemic Capillary Leak Syndrome.
Autor:
Albert C Sek, Zhihui Xie, Kaoru Terai, Lauren M Long, Celeste Nelson, Arkadiusz Z Dudek, Kirk M Druey
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137373 (2015)
Externí odkaz:
https://doaj.org/article/fd90a774d94841d782d3ad2d29a72353
Autor:
Danse Bi, Tuba Esfandyari, Christopher Jones, Roya Dolatkhah, Faris Farassati, Kyle Kimura, Allison Bright, Zhengian Liu, Mina Soleimani, Zohreh Sanaat, Kaoru Terai
Publikováno v:
Stem Cells. 36:1154-1169
The topic of cancer stem cells (CSCs) is of significant importance due to its implications in our understanding of the tumor biology as well as the development of novel cancer therapeutics. However, the question of whether targeting CSCs can hamper t
Autor:
Kevin F. Ginn, Kyle Kimura, Robyn Gartrell, Daniel Ziazadeh, Ben Fangman, Faris Farassati, Kaoru Terai, Emma Borrego-Diaz, Amanda L. Wise, Kushal J. Shah, Brandon Ricke, Sharad C. Mathur
Publikováno v:
Journal of Neuro-Oncology. 130:99-110
Medulloblastoma (MDB) represents a major form of malignant brain tumors in the pediatric population. A vast spectrum of research on MDB has advanced our understanding of the underlying mechanism, however, a significant need still exists to develop no
Autor:
Kristin E. Knutzen, Kaoru Terai, Austin K. Fuller, Jacob Kosyakovsky, Lucas Haase, Katherine A. Faltesek, William H. Frey, Leah R. Hanson, Jared M. Fine, Benjamin M. Stroebel, Tate J. Bowe
Publikováno v:
Neuroscience Letters. 714:134567
Emerging evidence continues to demonstrate that disrupted insulin signaling and altered energy metabolism may play a key role underpinning pathology in neurodegenerative conditions. Intranasally administered insulin has already shown promise as a mem
Autor:
Zhihui Xie, Lauren M. Long, Eunice C. Chan, Wei-Sheng Chen, Kirk M. Druey, Kaoru Terai, Timothy G. Myers, Yuzhi Yin, Arkadiusz Z. Dudek
Publikováno v:
Journal of leukocyte biology. 103(4)
Background Systemic Capillary Leak Syndrome (SCLS) is an extremely rare and life-threatening vascular disorder of unknown etiology. SCLS is characterized by abrupt and transient episodes of hypotensive shock and edema due to plasma leakage into perip
Publikováno v:
Oncotarget
Arylsulfatase B (ARSB; N-acetylgalactosamine 4-sulfatase) is reduced in several malignancies, but levels in melanoma have not been investigated previously. Experiments were performed in melanoma cell lines to determine ARSB activity and impact on mel
Autor:
Jorge Galvez, Kaoru Terai, Vidya Bodempudi, Arkadiusz Z. Dudek, Rachel Isaksson Vogel, David Land, Pawel Zwolak, Piotr Jasinski
Publikováno v:
Investigational New Drugs. 29:846-852
Molecular topology (MT) was used to develop quantitative structure-activity relationship (QSAR) models to screen databases for new anticancer compounds. One of the selected compounds was MT103, an isoborneol derivative, with a promising profile predi
Publikováno v:
Translational Research. 153:275-282
The insulin-like growth factor receptor is overexpressed on many types of cancer cells and has been implicated in metastasis and resistance to apoptosis. We report here the development of a novel covalent conjugate that contains the antifolate drug m