Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kaoru Sekihashi"'
Autor:
Yu F. Sasaki, Kazushige Hori, Ayako Saga, Kaoru Sekihashi, Hiromi Saitoh, Makoto Miyagawa, Munehiro Nakagawa
Publikováno v:
Environmental Mutagen Research. 25:83-86
Some mutagens are inactivated rapidly by components included in culture media, especially by serum. Long incubation periods may not be appropriate for the comet assay because DNA lesions may be repaired during the time that mutagens are inactivated,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92cc4d54e84df9362f7d048d87d67fa1
https://doi.org/10.3123/jems.25.83
https://doi.org/10.3123/jems.25.83
Autor:
Yukie Matsumura, Yu F. Sasaki, Mie Watanabe-Akanuma, Ayumu Yamamoto, Shunji Ueno, Kaoru Sekihashi, Shuji Tsuda, Fekadu Kassie, Siegfried Knasmüller
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 517:53-75
Mice and/or rats are usually used to detect chemical carcinogenicity and it has been known that there are species differences in carcinogenicity. To know whether there are species difference in genotoxicity, we conducted comparative investigation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6ec9b8c63a21e802120e104ed936bd6
https://doi.org/10.1016/s1383-5718(02)00034-7
https://doi.org/10.1016/s1383-5718(02)00034-7
Autor:
Kumiko Ishida, Shuji Tsuda, Youichi Miyamae, Kaoru Sekihashi, Naonori Matsusaka, Yu F. Sasaki, Hiroo Madarame, Mana Satoh
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 467:83-98
The genotoxicity of 22 mono-functional alkylating agents (including 9 dialkyl N-nitrosoamines) and 10 DNA crosslinkers selected from IARC (International Agency for Research on Cancer) groups 1, 2A, and 2B was evaluated in eight mouse organs with the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8163d4c01e904b3fa66667ad27870cbe
https://doi.org/10.1016/s1383-5718(00)00014-0
https://doi.org/10.1016/s1383-5718(00)00014-0
Autor:
Yu F. Sasaki, Kaoru Sekihashi, Noriko Kawamura, Naonori Matsusaka, Shuji Tsuda, Nobuyuki Susa, Hiroo Madarame, Kumiko Ishida, Shunji Ueno
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 465:11-26
The genotoxicity of 24 azo compounds selected from IARC (International Agency for Research on Cancer) groups 2A, 2B, and 3 were determined by the comet (alkaline single cell gel electrophoresis, SCG) assay in eight mouse organs. We treated groups of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbfa7fc2ebf8fbe9341036af42b1873
https://doi.org/10.1016/s1383-5718(99)00199-0
https://doi.org/10.1016/s1383-5718(99)00199-0
Autor:
Yu F. Sasaki, Kaoru Sekihashi, Shuji Tsuda, Emi Nishidate, Ayako Saga, Kumiko Ishida, Fusako Izumiyama
Publikováno v:
Critical Reviews in Toxicology. 30:629-799
The comet assay is a microgel electrophoresis technique for detecting DNA damage at the level of the single cell. When this technique is applied to detect genotoxicity in experimental animals, the most important advantage is that DNA lesions can be m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bfd43319b7a2f9ca7d97ef94463710c
https://doi.org/10.1080/10408440008951123
https://doi.org/10.1080/10408440008951123
Autor:
Aki Chiba, Makiko Tanaka, Sayuri Moribayashi, Yasuko Hara, Kaoru Sekihashi, Chihiro Kudou, Takanori Nakamura, YūF. Sasaki, Mikako Takahoko, Michiko Murakami, Yoshihisa Nakazawa, Shigenori Onizuka
Publikováno v:
Mutation Research/Genetic Toxicology. 371:203-214
The effect of Tochu tea, which is an aqueous extract of Eucommia ulmoides leaves and a popular beverage in Japan, on the urine mutagenicity before and after ingestion of raw fish and cooked beef was studied using Salmonella typhimurium YG1024. Urines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a86317f6fdfc5036eb55ea901cbcdd
https://doi.org/10.1016/s0165-1218(96)90108-1
https://doi.org/10.1016/s0165-1218(96)90108-1
Autor:
Takamasa Nonaka, Hajime Kobayashi, Yoichiro Arata, Sachie Nishizaki, Takashi Itagaki, Yuichiro Kezuka, Shun-ichi Kidokoro, Kaoru Sekihashi, Jun Hirabayashi, Ken-ichi Kasai
Publikováno v:
Protein and peptide letters. 15(4)
Galectin LEC-1 isolated from the nematode Caenorhabditis elegans was the first galectin found in invertebrates and also the first tandem-repeat-type galectin identified, containing two homologous carbohydrate-binding sites. This galectin is localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911ad6f071990179b084a175b92e3d06
https://pubmed.ncbi.nlm.nih.gov/18473958
https://pubmed.ncbi.nlm.nih.gov/18473958
Publikováno v:
The Journal of toxicological sciences. 27
The genotoxicity of steviol, a metabolite of stevia extract, was evaluated for its genotoxic potential using the comet assay. In an in vitro study, steviol at 62.5, 125, 250, and 500 micrograms/ml did not damage the nuclear DNA of TK6 and WTK1 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8d64ca997d5d1b08b7dc51581b0b58b3
https://pubmed.ncbi.nlm.nih.gov/12533916
https://pubmed.ncbi.nlm.nih.gov/12533916
Autor:
Kaoru Sekihashi, Takuro Sasaki, Shuji Tsuda, Yu F. Sasaki, Tsuguo Ikka, Ayumu Yamamoto, Kohtaro Kawamura
Publikováno v:
Mutation research. 493(1-2)
One of the important advantages of the comet assay is its ability to detect genotoxicity in many different organs. Since the exposure route of the test compounds is likely to influence the genotoxicity detected in a given organ, it is an important fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866e529176713daf455eb52af25130fe
https://pubmed.ncbi.nlm.nih.gov/11516714
https://pubmed.ncbi.nlm.nih.gov/11516714