Zobrazeno 1 - 10
of 704
pro vyhledávání: '"Kaoru Sato"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 18 (2024)
The blood–brain barrier (BBB) blocks harmful substances from entering the brain and dictates the central nervous system (CNS)-specific pharmacokinetics. Recent studies have shown that perivascular astrocytes and microglia also control BBB functions
Externí odkaz:
https://doaj.org/article/f8d7c493500b43c0b72bc45205182e0f
Autor:
Tetsuya Inoue, Yuichiro Yamamoto, Kaoru Sato, Yuko Okemoto-Nakamura, Yoshimi Shimizu, Motohiko Ogawa, Taishi Onodera, Yoshimasa Takahashi, Takaji Wakita, Mika K. Kaneko, Masayoshi Fukasawa, Yukinari Kato, Kohji Noguchi
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109363- (2024)
Summary: A current challenge is the emergence of SARS-CoV-2 variants, such as BQ.1.1 and XBB.1.5, that can evade immune defenses, thereby limiting antibody drug effectiveness. Emergency-use antibody drugs, including the widely effective bebtelovimab,
Externí odkaz:
https://doaj.org/article/249593eb8a2848489d26e0422c0f2000
Autor:
Sora Hayashida, Tatsuro Hagi, Miho Kobayashi, Ken-Ichi Kusumoto, Hideyuki Ohmori, Satoru Tomita, Satoshi Suzuki, Hideyuki Yamashita, Kaoru Sato, Takayuki Miura, Masaru Nomura
Publikováno v:
Journal of Dairy Science, Vol 106, Iss 10, Pp 6701-6709 (2023)
ABSTRACT: Koji mold, classified in the genus Aspergillus, is used to produce traditional Japanese fermented foods such as miso, soy sauce, and sake. In recent years, the application of koji mold to cheese ripening has attracted attention, and cheese
Externí odkaz:
https://doaj.org/article/5fa007a6538048b899710122c0564e1c
Autor:
Kanako Takahashi, Kaoru Sato
Publikováno v:
Membranes, Vol 14, Iss 4, p 77 (2024)
In our recent report, we clarified the direct interaction between the excitatory amino acid transporter (EAAT) 1/2 and polyunsaturated fatty acids (PUFAs) by applying electrophysiological and molecular biological techniques to Xenopus oocytes. Xenopu
Externí odkaz:
https://doaj.org/article/ea3fff1e49fd4f659d0d4184e5df9757
Autor:
Kimiko Nakayama-Kitamura, Yukari Shigemoto-Mogami, Hiroko Toyoda, Ikue Mihara, Hiroyuki Moriguchi, Hitoshi Naraoka, Tomomi Furihata, Seiichi Ishida, Kaoru Sato
Publikováno v:
Regenerative Therapy, Vol 22, Iss , Pp 192-202 (2023)
Microphysiological system (MPS), a new technology for in vitro testing platforms, have been acknowledged as a strong tool for drug development. In the central nervous system (CNS), the blood‒brain barrier (BBB) limits the permeation of circulating
Externí odkaz:
https://doaj.org/article/3a7be36fbabe4fde848f665ea305901f
Autor:
Kaoru Sato, Kazuhiko Hiramoto
Publikováno v:
IET Control Theory & Applications, Vol 17, Iss 4, Pp 433-445 (2023)
Abstract Advances in image processing technology have made it possible to measure the surface shape of the road ahead while driving. A new semi‐active suspension control method considering the forward road surface shape is proposed. A vehicle model
Externí odkaz:
https://doaj.org/article/c4ef5d743e0a42f4a5a7431fbf760b5e
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
While estrogens are well known for their pivotal role in the female reproductive system, they also play a crucial function in regulating physiological processes associated with learning and memory in the brain. Moreover, they have neuroprotective eff
Externí odkaz:
https://doaj.org/article/4dc35a37f16e4c5d88d33fb15185c63b
Autor:
Tatsuro Hagi, Atsushi Kurahashi, Yoshifumi Oguro, Kazuya Kodaira, Miho Kobayashi, Sora Hayashida, Hideyuki Yamashita, Yousuke Arakawa, Takayuki Miura, Kaoru Sato, Satoru Tomita, Satoshi Suzuki, Ken-Ichi Kusumoto, Naoko Moriya, Masaru Nomura
Publikováno v:
Journal of Dairy Science, Vol 105, Iss 6, Pp 4868-4881 (2022)
ABSTRACT: More than 2,000 varieties of cheese currently exist in the world, and cheese manufacture continues to flourish. To develop the cheese ripening process, additional ingredients are used during cheese production. In this study, the effect of s
Externí odkaz:
https://doaj.org/article/ae91abcd6b144bf3890c48885f62c2e5
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are caused by neuronal loss and dysfunction. Despite remarkable improvements in our understanding of these pathogenes
Externí odkaz:
https://doaj.org/article/a5ac27eef9c041e1ab097d81d28843de
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12605 (2023)
Human induced pluripotent stem cell (hiPSC)-derived neural cells have started to be used in safety/toxicity tests at the preclinical stage of drug development. As previously reported, hiPSC-derived neurons exhibit greater tolerance to excitotoxicity
Externí odkaz:
https://doaj.org/article/36cd9bd868e04c7ea31e9997bd1e5276