Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Kaoru Isa"'
Autor:
Masahiro Mitsuhashi, Reona Yamaguchi, Toshinari Kawasaki, Satoko Ueno, Yiping Sun, Kaoru Isa, Jun Takahashi, Kenta Kobayashi, Hirotaka Onoe, Ryosuke Takahashi, Tadashi Isa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Whether and how the non-lesional sensorimotor cortex is activated and contributes to post-injury motor recovery is controversial. Here, we investigated the role of interhemispheric pathway from the contralesional to ipsilesional premotor cor
Externí odkaz:
https://doaj.org/article/1b6bcb85086648e28ecb0b681dfcc717
Autor:
Kenta Yamauchi, Shinichiro Okamoto, Yoko Ishida, Kohtarou Konno, Kisara Hoshino, Takahiro Furuta, Megumu Takahashi, Masato Koike, Kaoru Isa, Masahiko Watanabe, Tadashi Isa, Hiroyuki Hioki
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Tyramide signal amplification (TSA) is a highly sensitive method for histochemical analysis. Previously, we reported a TSA system, biotinyl tyramine-glucose oxidase (BT-GO), for bright-filed imaging. Here, we develop fluorochromized tyramide
Externí odkaz:
https://doaj.org/article/de14391ad4aa4ee1ac5b140c4236f532
Autor:
Norihiro Takakuwa, Kaoru Isa, Reona Yamaguchi, Hirotaka Onoe, Jun Takahashi, Masatoshi Yoshida, Tadashi Isa
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101960- (2023)
Summary: Patients with damage to the primary visual cortex (V1) can respond correctly to visual stimuli in their lesion-affected visual field above the chance level, an ability named blindsight. Here, we present a protocol for making an animal model
Externí odkaz:
https://doaj.org/article/273f3c4188614876b73e11f9a2e9793a
Autor:
Yasumi Ohta, Mark Christian Guinto, Takashi Tokuda, Mamiko Kawahara, Makito Haruta, Hironari Takehara, Hiroyuki Tashiro, Kiyotaka Sasagawa, Hirotaka Onoe, Reona Yamaguchi, Yoshinori Koshimizu, Kaoru Isa, Tadashi Isa, Kenta Kobayashi, Yasemin M. Akay, Metin Akay, Jun Ohta
Publikováno v:
IEEE Access, Vol 9, Pp 127937-127949 (2021)
Optogenetics is a powerful tool for controlling biological functions using light. Optical fibers have been extensively utilized in optical stimulation devices for optogenetics. However, the use of optical fibers results in a small photo-stimulation r
Externí odkaz:
https://doaj.org/article/c817aae2c6ff4211a1a582b24ada8946
Autor:
Etsuo A. Susaki, Chika Shimizu, Akihiro Kuno, Kazuki Tainaka, Xiang Li, Kengo Nishi, Ken Morishima, Hiroaki Ono, Koji L. Ode, Yuki Saeki, Kazunari Miyamichi, Kaoru Isa, Chihiro Yokoyama, Hiroki Kitaura, Masako Ikemura, Tetsuo Ushiku, Yoshihiro Shimizu, Takashi Saito, Takaomi C. Saido, Masashi Fukayama, Hirotaka Onoe, Kazushige Touhara, Tadashi Isa, Akiyoshi Kakita, Mitsuhiro Shibayama, Hiroki R. Ueda
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-22 (2020)
Tissue clearing has revolutionised histology, but limited penetration of antibodies and stains into thick tissue segments is still a bottleneck. Here, the authors characterise optically cleared tissue as an electrolyte gel and apply this knowledge to
Externí odkaz:
https://doaj.org/article/fef62ea755aa42a98c3b75bb70274b5d
Autor:
Kaoru Isa, Kota Tokuoka, Sakura Ikeda, Sara Karimi, Kenta Kobayashi, Thongchai Sooksawate, Tadashi Isa
Publikováno v:
Frontiers in Neural Circuits, Vol 15 (2022)
In our previous study, we showed that the defense responses induced by the selective optogenetic activation of the uncrossed output pathway from the deeper layer of the superior colliculus were environment dependent in the mouse. In a small closed bo
Externí odkaz:
https://doaj.org/article/87383db613ec4aacaedbfd056eb51e7c
Autor:
Takahiro Furuta, Kenta Yamauchi, Shinichiro Okamoto, Megumu Takahashi, Soichiro Kakuta, Yoko Ishida, Aya Takenaka, Atsushi Yoshida, Yasuo Uchiyama, Masato Koike, Kaoru Isa, Tadashi Isa, Hiroyuki Hioki
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103601- (2022)
Summary: The mammalian brain is organized over sizes that span several orders of magnitude, from synapses to the entire brain. Thus, a technique to visualize neural circuits across multiple spatial scales (multi-scale neuronal imaging) is vital for d
Externí odkaz:
https://doaj.org/article/708868f67aef4da0999575f7cce6ba6e
Autor:
Masaharu Kinoshita, Rikako Kato, Kaoru Isa, Kenta Kobayashi, Kazuto Kobayashi, Hirotaka Onoe, Tadashi Isa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Blindsight refers to visual behaviours that are spared following lesions to the primary visual cortex and is thought to involve pulvinar circuits. Here, the authors report that selective inactivation of the ventral pulvinar or the superior colliculus
Externí odkaz:
https://doaj.org/article/500073790e6e40a28486840572180477
Autor:
Masanori Sawamura, Hirotaka Onoe, Hideo Tsukada, Kaoru Isa, Hodaka Yamakado, Shinya Okuda, Masashi Ikuno, Yusuke Hatanaka, Shigeo Murayama, Norihito Uemura, Tadashi Isa, Ryosuke Takahashi
Publikováno v:
Movement Disorders. 37(10):2033-2044
[Background] Lewy body diseases (LBDs), which are pathologically defined as the presence of intraneuronal α-synuclein (α-Syn) inclusions called Lewy bodies, encompass Parkinson's disease, Parkinson's disease with dementia, and dementia with Lewy bo
Autor:
Ryo Sasaki, Yasumi Ohta, Hirotaka Onoe, Reona Yamaguchi, Takeshi Miyamoto, Takashi Tokuda, Yuki Tamaki, Kaoru Isa, Jun Takahashi, Kenta Kobayashi, Jun Ohta, Tadashi Isa
Publikováno v:
Science; 1/5/2024, Vol. 383 Issue 6678, p55-61, 7p, 5 Diagrams