Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Kaoru, Shimokata"'
Autor:
Yoshitaka Sekido, Jean-Pierre J. Issa, Takumi Kishimoto, Nobukazu Fujimoto, Toyoaki Hida, Keitaro Matsuo, Kaoru Shimokata, Yoshinori Hasegawa, Masashi Kondo, Noriyasu Usami, Tetsuo Taniguchi, Hirotaka Osada, Hideki Murakami, Makiko Fujii, Byonggu An, Wentao Gao, Hiromu Suzuki, Minoru Toyota, Lanlan Shen, Yutaka Kondo, Keiko Shinjo, Yasuhiro Goto
Malignant pleural mesothelioma (MPM) is a fatal thoracic malignancy, the epigenetics of which are poorly defined. We performed high-throughput methylation analysis covering 6,157 CpG islands in 20 MPMs and 20 lung adenocarcinomas. Newly identified ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832adae405cb5e08c36f72afc82b8458
https://doi.org/10.1158/0008-5472.c.6500178
https://doi.org/10.1158/0008-5472.c.6500178
Autor:
Yoshitaka Sekido, Jean-Pierre J. Issa, Takumi Kishimoto, Nobukazu Fujimoto, Toyoaki Hida, Keitaro Matsuo, Kaoru Shimokata, Yoshinori Hasegawa, Masashi Kondo, Noriyasu Usami, Tetsuo Taniguchi, Hirotaka Osada, Hideki Murakami, Makiko Fujii, Byonggu An, Wentao Gao, Hiromu Suzuki, Minoru Toyota, Lanlan Shen, Yutaka Kondo, Keiko Shinjo, Yasuhiro Goto
Supplementary Figures 1-3, Tables 1-5 from Epigenetic Profiles Distinguish Malignant Pleural Mesothelioma from Lung Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebbba568dd36d8da23649d9a0ca5220
https://doi.org/10.1158/0008-5472.22382367
https://doi.org/10.1158/0008-5472.22382367
Autor:
Toyokazu Sashio, Hiroaki Kume, Naoya Takeda, Toshiaki Asano, Seita Tsuji, Masashi Kondo, Yoshinori Hasegawa, Kaoru Shimokata
Publikováno v:
Allergology International, Vol 61, Iss 2, Pp 283-293 (2012)
Background: Sphingosine-1-phosphate (S1P), a lysophospholipid released from inflammatory cells, causes cell migration by increasing cytokines and chemokines. This study was designed to determine whether S1P causes adherence of eosinophils to pulmonar
Externí odkaz:
https://doaj.org/article/71d36080c4ed48e38aaa70988aeec893
Autor:
Ryujiro Suzuki, Masashi Yamamoto, Kosuke Takahashi, Yoshimasa Tanikawa, Hiroyuki Taniguchi, Joe Shindoh, Kazuyoshi Imaizumi, Motoyasu Okuno, Hideo Saka, Hiroshi Saito, Yoshinori Hasegawa, Kaoru Shimokata
Publikováno v:
Journal of Infection and Chemotherapy. 20:365-369
We assessed the efficacy and safety of cefepime monotherapy (1 g intravenously every 8 h) for febrile neutropenia in patients with lung cancer in a multi-institutional phase II study. Patients treated with chemotherapy with or without radiotherapy fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a666459a59ee1fdc9e051125cac336e
https://doi.org/10.1016/j.jiac.2014.02.002
https://doi.org/10.1016/j.jiac.2014.02.002
Autor:
Masashi Kondo, Mitsuo Sato, Naozumi Hashimoto, Yukihiro Noda, Tsutomu Kawabe, Kaoru Shimokata, Naoyuki Imai, Kazuyoshi Imaizumi, Tomomi Ogawa, Yoshinori Hasegawa, Masaki Matsuo, Izumi Hashimoto, Satoru Ito, Toyohiro Honda, Hiroshi Furukawa
Publikováno v:
Respirology. 18:340-347
Background and objective: Bronchiolitis obliterans (BO) has been reported to develop following ingestion of Sauropus androgynus (SA), a leafy shrub distributed in Southeast Asia. Little is known about direct effects of SA on airway resident cells or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5c259ff6fcd44365f62a1e691f3989
https://doi.org/10.1111/j.1440-1843.2012.02286.x
https://doi.org/10.1111/j.1440-1843.2012.02286.x
Autor:
Toru Hara, Naozumi Hashimoto, Yoshinori Hasegawa, Tamio Ohno, Kaoru Shimokata, Tsutomu Kawabe, Miyoko Matsushima, Masahiko Nishimura, Kazuyoshi Imaizumi, Masakazu Okamoto
Publikováno v:
Immunogenetics. 65:17-24
Asthma is regarded as a multifactorial inflammatory disorder arising as a result of inappropriate immune responses in genetically susceptible individuals to common environmental antigens. However, the precise molecular basis is unknown. To identify g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbc0270da958fa8b645e5e0b3c76e035
https://doi.org/10.1007/s00251-012-0656-7
https://doi.org/10.1007/s00251-012-0656-7
Autor:
Akiko Noda, Masato Okuda, Fumihiko Yasuma, Kaoru Shimokata, Yuki Fujii, Seiko Miyata, Chie Nakazaki, Shigeaki Hinohara, Tsutomu Nakashima, Hironao Otake, Seiichi Nakata, Atsuko Maekawa, Yasuo Koike
Publikováno v:
The Open General and Internal Medicine Journal. 5:9-12
The rapid improvement in blood oxygenation has been observed in patients with acute respiratory failure placed in a prone position. The gravitational effect relieves upper airway narrowing in the prone position, resulting in an improvement in sleep q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::314b40995917f82aaf2e7d1570dacccb
https://doi.org/10.2174/1874076601205010009
https://doi.org/10.2174/1874076601205010009
Autor:
Masataka Shibasaki, Naozumi Hashimoto, Yoshinori Hasegawa, Kazuyoshi Imaizumi, Kaoru Shimokata, Tsutomu Kawabe, Yuta Hayashi, Toshinobu Nakamura, Miyoko Matsushima
Publikováno v:
Biochemical and Biophysical Research Communications. 417:169-174
The lung is a primary target for oxygen toxicity because of its constant exposure to high oxygen levels and environmental oxidants. Quercetin is one of the most commonly found dietary flavonoids, and it provides cytoprotective actions via activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88173a33829ecf18d07e76915d83648d
https://doi.org/10.1016/j.bbrc.2011.11.078
https://doi.org/10.1016/j.bbrc.2011.11.078
Autor:
Naozumi Hashimoto, Toshinobu Nakamura, Kaoru Shimokata, Tsutomu Kawabe, Yoshinori Hasegawa, Masataka Shibasaki, Kazuyoshi Imaizumi, Yuta Hayashi, Miyoko Matsushima
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:614-620
Quercetin is a flavonoid with a wide variety of cytoprotective and modulatory functions. Heme oxygenase-1 (HO-1) is an inducible enzyme. Its reaction product, carbon monoxide (CO), confers cellular protection in a number of conditions and diseases as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920984a6c22097110a53c93e28851ecf
https://doi.org/10.1165/rcmb.2010-0338oc
https://doi.org/10.1165/rcmb.2010-0338oc
Autor:
Yoshinori Hasegawa, Harunori Nakashima, Naozumi Hashimoto, Sem H. Phan, Kaoru Shimokata, Kazuyoshi Imaizumi, Tsutomu Kawabe, Masaki Matsuo
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 43:161-172
The pathological hallmark lesions in idiopathic pulmonary fibrosis are the fibroblastic foci, in which fibroblasts are thought to be involved in the tissue remodeling, matrix deposition, and cross-talk with alveolar epithelium. Recent evidence indica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cb03448605bed9a8d6ecf7bd464d71
https://doi.org/10.1165/rcmb.2009-0031oc
https://doi.org/10.1165/rcmb.2009-0031oc