Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kaori Takama"'
Autor:
Masato Ohbuchi, Kaori Takama, Shunji Yamazaki, Akira Fujimori, Kazuhiro Tetsuka, Takayuki Goto, Fumiko Kiyonaga, Tetsuhiro Kawabe
Publikováno v:
Biologicalpharmaceutical bulletin. 43(3)
Recent progress in the fields of tissue engineering, micro-electro mechanical systems, and materials science have greatly improved cell culture systems, which were traditionally performed in a static two-dimensional manner. This progress has led to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90cfc80486bb687169794516b75c8e6
https://pubmed.ncbi.nlm.nih.gov/32115499
https://pubmed.ncbi.nlm.nih.gov/32115499
Autor:
Takeshi Nakamura, Kaori Takama, Dorien Groenendaal, Radboud van Trigt, Yoshiaki Ohtsu, Kiyoshi Noguchi, Akitsugu Takada
Publikováno v:
Chromatographia. 80:217-227
This is a case study of the difficulties caused by supersaturation of an analyte during the quantification of a drug in urine. To support the clinical development of the potent helicase–primase inhibitor ASP2151, we developed and validated simple a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a69f0116fd579e7559b692311f9c97c
https://doi.org/10.1007/s10337-016-3236-4
https://doi.org/10.1007/s10337-016-3236-4
Autor:
Wataru Hamaguchi, Kaori Takama, Kiyohiro Samizu, Takuma Mihara, Naoyuki Masuda, Toshihiro Watanabe
Publikováno v:
Chemical and Pharmaceutical Bulletin. 62:1200-1213
A novel class of phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability in mouse liver microsomes were designed and synthesized starting from 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline (MP-10). Repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9877dc6c89ebb4477ac5fad4ce9f6d50
https://doi.org/10.1248/cpb.c14-00509
https://doi.org/10.1248/cpb.c14-00509
Autor:
Tomomi Furihata, Kaori Takama, Kaoru Kobayashi, Kan Chiba, Tomoaki Higuchi, Masakiyo Hosokawa, Sachiyo Kawashima
Publikováno v:
Drug Metabolism and Disposition. 34:1012-1018
CYP2C9 and CYP2C19 are clinically important drug-metabolizing enzymes. The expression level of CYP2C9 is much higher than that of CYP2C19, although the factor(s) responsible for the difference between the expression levels of these genes is still unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f81accee8853ae77d618149c6acaa09
https://doi.org/10.1124/dmd.106.009365
https://doi.org/10.1124/dmd.106.009365
Autor:
Wataru, Hamaguchi, Naoyuki, Masuda, Kiyohiro, Samizu, Takuma, Mihara, Kaori, Takama, Toshihiro, Watanabe
Publikováno v:
Chemicalpharmaceutical bulletin. 62(12)
A novel class of phosphodiesterase 10A (PDE10A) inhibitors with improved metabolic stability in mouse liver microsomes were designed and synthesized starting from 2-({4-[1-methyl-4-(pyridin-4-yl)-1H-pyrazol-3-yl]phenoxy}methyl)quinoline (MP-10). Repl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec04b4ec2913d80c7268ced00ca35637
https://pubmed.ncbi.nlm.nih.gov/25450629
https://pubmed.ncbi.nlm.nih.gov/25450629