Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kaori Hosoda"'
Publikováno v:
Pharmacology Research & Perspectives
Equol is a product formed during the biotransformation of the naturally occurring isoflavone daidzein by intestinal bacteria. The role of equol in the prevention of several hormone‐dependent diseases such as prostate cancer and osteoporosis as well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d453ed081e4c2906120bc137a99896
http://europepmc.org/articles/PMC6507113
http://europepmc.org/articles/PMC6507113
Publikováno v:
Analytical and Bioanalytical Chemistry. 397:1563-1572
Much attention has been paid to the metabolism and disposition of isoflavones daidzein (Dein) and genistein (Gein) with regard to the prevention of several hormone-dependent diseases. Recent studies have reported that several conjugates as well as ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ba1cd75d8f6bf333e2370de4e84309
https://doi.org/10.1007/s00216-010-3714-8
https://doi.org/10.1007/s00216-010-3714-8
Publikováno v:
Pharmacology Research & Perspectives; Jun2019, Vol. 7 Issue 3, p1-11, 11p
Autor:
Hiromi Shibasaki, Mari Goto, Atsushi Suzuki, Kazuo Ishii, Takashi Furuta, Akitomo Yokokawa, Kaori Hosoda
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 41(2)
This study was designed to evaluate the in vivo activity of cytochrome P450 3A (CYP3A) in 49 healthy Japanese subjects aged 22-58 years using endogenous cortisol 6β-hydroxylation clearance [CLm(6β)], a novel biomarker for CYP3A phenotyping. CLm(6β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d27aef4cef7d839ee1e49ad687ae7efe
https://pubmed.ncbi.nlm.nih.gov/23175666
https://pubmed.ncbi.nlm.nih.gov/23175666
Several methods for the determination of glucuronic acid- and/or sulfuric acid-conjugated metabolites of daidzein and genistein in human plasma have been reported. The methods can be classified into two general types: direct and indirect assays of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90e15b6750e1b3a2e0e1ca24aa4f537
https://doi.org/10.1039/9781849735094-00196
https://doi.org/10.1039/9781849735094-00196
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 39(9)
Isoflavone aglycones daidzein (Dein) and genistein (Gein) are present primarily as glucuronides and sulfates in human plasma; however, very little is known about the plasma pharmacokinetics of isoflavone conjugates after soy ingestion. The aim of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c317597fb01835c74ea5d0726c2272d4
https://pubmed.ncbi.nlm.nih.gov/21622628
https://pubmed.ncbi.nlm.nih.gov/21622628
Autor:
Akira Hiratsuka, Kazuo Ishii, Kenichiro Ogura, Takashi Furuta, Akitomo Yokokawa, Kaori Hosoda
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 36(8)
The roles of isoflavones in the prevention of several hormone-dependent cancers and osteoporosis are of great interest. Despite many pharmacokinetics studies of the isoflavones, the actual types of conjugates circulating in the body and the position(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d996c065a290134ef1ae53073bce2e
https://pubmed.ncbi.nlm.nih.gov/18443032
https://pubmed.ncbi.nlm.nih.gov/18443032