Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Kaori Sakamoto"'
Autor:
Robert M. Cox, Josef D. Wolf, Nicole A. Lieberman, Carolin M. Lieber, Hae-Ji Kang, Zachary M. Sticher, Jeong-Joong Yoon, Meghan K. Andrews, Mugunthan Govindarajan, Rebecca E. Krueger, Elizabeth B. Sobolik, Michael G. Natchus, Andrew T. Gewirtz, Rik L. deSwart, Alexander A. Kolykhalov, Khan Hekmatyar, Kaori Sakamoto, Alexander L. Greninger, Richard K. Plemper
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Measles cases have surged pre-COVID-19 and the pandemic has aggravated the problem. Most measles-associated morbidity and mortality arises from destruction of pre-existing immune memory by measles virus (MeV), a paramyxovirus of the morbilli
Externí odkaz:
https://doaj.org/article/c318e8440b28489e92886789df7a2812
Autor:
Andrew R. Moorhead, Christopher C. Evans, Kaori Sakamoto, Michael T. Dzimianski, Abdelmoneim Mansour, Utami DiCosty, Crystal Fricks, Scott McCall, Ben Carson, C. Thomas Nelson, John W. McCall
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Background The American Heartworm Society canine guidelines recommend treatment with doxycycline prior to adulticide administration to reduce levels of Wolbachia and its associated metabolites, which are known to be a leading cause of pulmon
Externí odkaz:
https://doaj.org/article/0b7512faaf6a4602968a09f1f167ece9
Autor:
Carolin M. Lieber, Robert M. Cox, Julien Sourimant, Josef D. Wolf, Kate Juergens, Quynh Phung, Manohar T. Saindane, Meghan K. Smith, Zachary M. Sticher, Alexander A. Kalykhalov, Michael G. Natchus, George R. Painter, Kaori Sakamoto, Alexander L. Greninger, Richard K. Plemper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Molnupiravir was the first orally available SARS-CoV-2 antiviral approved for outpatient use against SARS-CoV-2, but its efficacy against variants of concern, especially delta, was questioned. Here the authors evaluate molnupiravir against variant of
Externí odkaz:
https://doaj.org/article/4980daa3f2c04201ae020f4e00503ea0
Autor:
Carolin M Lieber, Megha Aggarwal, Jeong-Joong Yoon, Robert M Cox, Hae-Ji Kang, Julien Sourimant, Mart Toots, Scott K Johnson, Cheryl A Jones, Zachary M Sticher, Alexander A Kolykhalov, Manohar T Saindane, Stephen M Tompkins, Oliver Planz, George R Painter, Michael G Natchus, Kaori Sakamoto, Richard K Plemper
Publikováno v:
PLoS Pathogens, Vol 19, Iss 4, p e1011342 (2023)
Influenza outbreaks are associated with substantial morbidity, mortality and economic burden. Next generation antivirals are needed to treat seasonal infections and prepare against zoonotic spillover of avian influenza viruses with pandemic potential
Externí odkaz:
https://doaj.org/article/6936c60659ba4a96b921b668517dfbee
Autor:
Tuhina Gupta, Demba Sarr, Kayla Fantone, Nuha Milad Ashtiwi, Kaori Sakamoto, Frederick D. Quinn, Balázs Rada
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMycobacterium tuberculosis (Mtb) is the primary cause of human tuberculosis (TB) and is currently the second most common cause of death due to a singleinfectious agent. The first line of defense against airborne pathogens, including Mtb,
Externí odkaz:
https://doaj.org/article/5d27c5154f804d7480a104cb4c550d89
Bovine tuberculosis in African buffalo (Syncerus caffer): Progression of pathology during infection.
Autor:
Hilary Ann Lakin, Hannah Tavalire, Kaori Sakamoto, Peter Buss, Michele Miller, Sarah A Budischak, Kristina Raum, Vanessa O Ezenwa, Brianna Beechler, Anna Jolles
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 11, p e0010906 (2022)
BackgroundBovine tuberculosis (BTB) is a zoonotic disease of global importance endemic in African buffalo (Syncerus caffer) in sub-Saharan Africa. Zoonotic tuberculosis is a disease of global importance, accounting for over 12,000 deaths annually. Ca
Externí odkaz:
https://doaj.org/article/923995b0e9c149ab8d7b581eaec1f2ab
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Excessive inflammation in patients with severe influenza disease may lead to acute lung injury that results in acute respiratory distress syndrome (ARDS). ARDS is associated with alveolar damage and pulmonary edema that severely impair gas e
Externí odkaz:
https://doaj.org/article/70a6d14eeee34cc5b7768114305903de
Autor:
Tuhina Gupta, Naveen Somanna, Thomas Rowe, Monica LaGatta, Shelly Helms, Simon Odera Owino, Tomislav Jelesijevic, Stephen Harvey, Wayne Jacobs, Thomas Voss, Kaori Sakamoto, Cheryl Day, Christopher Whalen, Russell Karls, Biao He, S. Mark Tompkins, Abhijeet Bakre, Ted Ross, Frederick D. Quinn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Even with the COVID-19 pandemic, tuberculosis remains a leading cause of human death due to a single infectious agent. Until successfully treated, infected individuals may continue to transmit Mycobacterium tuberculosis bacilli to contacts. As with o
Externí odkaz:
https://doaj.org/article/bac15bebae5d430ea77a8a4d1409cd23
Autor:
Christopher C. Evans, Katherine M. Day, Yi Chu, Bridget Garner, Kaori Sakamoto, Andrew R. Moorhead
Publikováno v:
Parasites & Vectors, Vol 14, Iss 1, Pp 1-10 (2021)
Abstract Background The Mongolian jird (Meriones unguiculatus) has long been recognized as a permissive host for the filarial parasite Brugia malayi; however, it is nonpermissive to another filarial parasite, canine heartworm (Dirofilaria immitis). B
Externí odkaz:
https://doaj.org/article/96d9d50f22c346e391f74099c1a15048
Autor:
Molly D. Savadelis, Amanda E. Coleman, Gregg S. Rapoport, Ajay Sharma, Kaori Sakamoto, Deborah A. Keys, Cameon M. Ohmes, Joe A. Hostetler, Michael T. Dzimianski, Andrew R. Moorhead
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 5, Pp 1734-1745 (2020)
Abstract Background Administration of moxidectin topically and doxycycline PO has been utilized experimentally as an alternative treatment for heartworm disease. However, clinical effects of this protocol remain poorly characterized. Objective To eva
Externí odkaz:
https://doaj.org/article/0a35c91886fe4fe4b9caa53d47fd36ff