Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Kaomei, Guan"'
Autor:
Juliane Hannemann, Katrin Wasser, Yoana Mileva, Fiona Kleinsang, Mario Schubert, Edzard Schwedhelm, Kaomei Guan, Rolf Wachter, Rainer Böger
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 17 (2024)
Background Atrial fibrillation (AF) is a stroke risk factor that often remains undetected at hospital admission. Long‐term Holter monitoring helps to identify patients with previously unrecognized AF. Asymmetric (ADMA) and symmetric dimethylarginin
Externí odkaz:
https://doaj.org/article/70f7f2dad8af4eb195e2aa580ffe32bb
Autor:
Erik Klapproth, Anke Witt, Pauline Klose, Johanna Wiedemann, Nikitha Vavilthota, Stephan R. Künzel, Susanne Kämmerer, Mario Günscht, David Sprott, Mathias Lesche, Fabian Rost, Andreas Dahl, Erik Rauch, Lars Kattner, Silvio Weber, Peter Mirtschink, Irakli Kopaliani, Kaomei Guan, Kristina Lorenz, Paul Saftig, Michael Wagner, Ali El-Armouche
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Therapeutic interference with the immune response after myocardial infarction holds the potential to close a clinically relevant gap. Here, the authors show that inhibition of a cardiomyocyte-specific ADAM10 / CX3CL1 axis improves post infarction sur
Externí odkaz:
https://doaj.org/article/8d786fd470964db7bb4c1cae17ec3150
Autor:
Binh Y. Nguyen, Fangchao Zhou, Pablo Binder, Wei Liu, Susanne S. Hille, Xiaojing Luo, Min Zi, Hongyuan Zhang, Antony Adamson, Fozia Z. Ahmed, Sam Butterworth, Elizabeth J. Cartwright, Oliver J. Müller, Kaomei Guan, Elizabeth M. Fitzgerald, Xin Wang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background Prolonged activation of angiotensin II is the main mediator that contributes to the development of heart diseases, so converting angiotensin II into angiotensin 1‐7 has emerged as a new strategy to attenuate detrimental effects of angiot
Externí odkaz:
https://doaj.org/article/0de15311822a4ff99e0f184b803b44a8
Autor:
Gunnar Weninger, Tatiana Pochechueva, Dana El Chami, Xiaojing Luo, Tobias Kohl, Sören Brandenburg, Henning Urlaub, Kaomei Guan, Christof Lenz, Stephan E. Lehnart
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Calpains are calcium-activated neutral proteases involved in the regulation of key signaling pathways. Junctophilin-2 (JP2) is a Calpain-specific proteolytic target and essential structural protein inside Ca2+ release units required for exci
Externí odkaz:
https://doaj.org/article/4776fbc39c47406b95dc5134504a6b9e
Publikováno v:
Heliyon, Vol 8, Iss 9, Pp e10365- (2022)
The combination of the human induced pluripotent stem cell (hiPSC) and organoid technology enables the generation of human 3D culture systems, providing the opportunity to model human tissue-like structures in vitro. This protocol offers the details
Externí odkaz:
https://doaj.org/article/7a2e3177805842fbbd172e70d251bb7f
Autor:
Francesca Murganti, Wouter Derks, Marion Baniol, Irina Simonova, Palina Trus, Katrin Neumann, Shahryar Khattak, Kaomei Guan, Olaf Bergmann
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
One of the major goals in cardiac regeneration research is to replace lost ventricular tissue with new cardiomyocytes. However, cardiomyocyte proliferation drops to low levels in neonatal hearts and is no longer efficient in compensating for the loss
Externí odkaz:
https://doaj.org/article/9a97d389d0f2464d88479a76c4e7860d
Autor:
Pablo Binder, Binh Nguyen, Lucy Collins, Min Zi, Wei Liu, Foteini Christou, Xiaojing Luo, Susanne S. Hille, Norbert Frey, Elizabeth J. Cartwright, Jonathan Chernoff, Oliver J. Müller, Kaomei Guan, Xin Wang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Endoplasmic Reticulum (ER) stress and oxidative stress have been highly implicated in the pathogenesis of cardiac hypertrophy and heart failure (HF). However, the mechanisms involved in the interplay between these processes in the heart are not fully
Externí odkaz:
https://doaj.org/article/cf127567c6ca4514b48d2a9c96e5f4e9
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102565- (2021)
Recently, there have been great advances in cardiovascular channelopathy modeling and drug safety pharmacology using human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). The automated patch-clamp (APC) technique overcomes the disadv
Externí odkaz:
https://doaj.org/article/7887c497b2d548b08bc98d7f4f99e75b
Autor:
Wener Li, Sarah Henze, Xiaojing Luo, Ying Ulbricht, Anja Richter, Nataliya Di Donato, Arthur A.M. Wilde, Kaomei Guan
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102259- (2021)
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a severe inheritable cardiac disorder, which is characterized by life-threatening cardiac arrhythmias, syncope, seizures, or sudden cardiac death in response to physical exercise or emot
Externí odkaz:
https://doaj.org/article/689c830c4748464aa6af631e5412e926
Autor:
Chao Yi, Tim WGM Spitters, Ezz Al-Din Ahmed Al-Far, Sen Wang, TianLong Xiong, Simian Cai, Xin Yan, Kaomei Guan, Michael Wagner, Ali El-Armouche, Christopher L Antos
Publikováno v:
eLife, Vol 10 (2021)
The increase in activity of the two-pore potassium-leak channel Kcnk5b maintains allometric juvenile growth of adult zebrafish appendages. However, it remains unknown how this channel maintains allometric growth and how its bioelectric activity is re
Externí odkaz:
https://doaj.org/article/7348d8ea1e6e41b1b7721c4f46973f84