Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Kanya Tonda"'
Autor:
Takuji Mizui, Tsutomu Shike, Junko Higaki, Seijiro Hara, Kenji Miyata, Nobuo Takasu, Kiyoshi Nagata, Kanya Tonda
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 18(8)
Abstract —The ileal Na + /bile acid cotransporter (IBAT) plays an important role in the enterohepatic circulation of bile acids. We investigated the effects of IBAT inhibition on the maintenance of serum cholesterol level by using a novel IBAT inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928ebee7b2fc60bc652fe6e716921d6f
https://pubmed.ncbi.nlm.nih.gov/9714138
https://pubmed.ncbi.nlm.nih.gov/9714138
Autor:
Kenji Miyata, Takuji Mizui, Seijiro Hara, Ken-ichi Higashino, Yasumasa Goh, Kanya Tonda, Nobuo Takasu, Mie Iwai, Junko Higaki, Kiyoshi Nagata
Publikováno v:
Life sciences. 60(24)
The ileal Na+/bile acid cotransporter (IBAT) maintains the reabsorption of bile acids from the intestine in the enterohepatic circulation of bile acids. In the present study, we showed that S-8921 could dose-dependently inhibit the uptake of [ 3 H]ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521b58fdf28f767d0036dd1273cce0de
https://pubmed.ncbi.nlm.nih.gov/9188770
https://pubmed.ncbi.nlm.nih.gov/9188770
Publikováno v:
Steroids. 58(2)
The inhibitory effect of SSF-109 on cholesterol synthesis in isolated hepatocytes was studied using a radio-high-performance liquid chromatography system, and the results were compared with those of other inhibitors, triparanol and AMO-1618. SSF-109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71e8ca99a647b00a465fa52d958693e
https://pubmed.ncbi.nlm.nih.gov/8484187
https://pubmed.ncbi.nlm.nih.gov/8484187
Autor:
Kanya Tonda, Masaharu Hirata
Publikováno v:
Chemico-biological interactions. 77(2)
Effects of phenobarbital (PB) and l -methionine on 2-carboxybenzaldehyde (CBA) reductase in rat hepatocyte primary culture were examined. Inclusion of PB in the culture medium markedly enhanced the CBA reductase activity while l -methionine, which el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9c10122b8bdadd1b3d3cbcb8861bb8
https://pubmed.ncbi.nlm.nih.gov/1991334
https://pubmed.ncbi.nlm.nih.gov/1991334
Publikováno v:
Japanese Journal of Pharmacology. 76:106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ad142495eb00095477adbe315894052
https://doi.org/10.1016/s0021-5198(19)40544-1
https://doi.org/10.1016/s0021-5198(19)40544-1
Autor:
Atsuko Uomori, Yasuyoshi Takeuchi, Kanya Tonda, Hiroyuki Saito, Masaharu Hirata, Ushio Sankawa, Yohko Yoshimura, Yasuhiro Nishibe, Haruo Seto, Ken'ichi Takeda, Hiroshi Noguchi, Shujiro Seo, Yutaka Ebizuka
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2065
Since isolated dog hepatocytes have been shown to exhibit potent activity for the synthesis of cholesterol from acetic acid, an analysis of cholesterol and lanosterol biosynthesized from [1,2-13C2]- or [2-13C2H3] acetate in fresh isolated hepatocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c77352d174995e51e7cd12667af4c95c
https://doi.org/10.1039/p19910002065
https://doi.org/10.1039/p19910002065
Drug interactions in biotransformation of 1-phthalidyl 5-fluorouracil to 5-fluorouracil in rat liver
Autor:
Kanya Tonda, Masaharu Hirata
Publikováno v:
Chemico-Biological Interactions. 52:141-150
Two rat liver hydrolases were found to be involved in the metabolism of 1-phthalidyl 5-fluorouracil (PH-FU) to 5-fluorouracil (5-FU), one of which was induced by phenobarbital (PB) treatment of rats. Both inducible and constitutive enzyme were solubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30aead0652f6e5cf3d0db7ae2b9808c3
https://doi.org/10.1016/0009-2797(84)90068-1
https://doi.org/10.1016/0009-2797(84)90068-1
Publikováno v:
Japanese Journal of Pharmacology. 28:205-211
Effects of l-methyl-2-(β-naphthyl)-aziridine (250059-S), which possesses characteristic tranquilizing actions, on levels of blood glucose and liver glycogen, and on adrenaline release from the adrenal gland were studied in rats. While there was no e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d1985ebf9a5d764d90251eced577fa2
https://doi.org/10.1254/jjp.28.205
https://doi.org/10.1254/jjp.28.205
Autor:
Toshio YOSHIZAKI, Kanya TONDA
Publikováno v:
Japanese Journal of Pharmacology. 31:443-450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f4c73ce06883cb019f311c3f1c2aa8
https://doi.org/10.1016/s0021-5198(19)52851-7
https://doi.org/10.1016/s0021-5198(19)52851-7
Publikováno v:
Biochemical and Biophysical Research Communications. 112:356-360
The metabolism of 2-bromoethylaminonaphthoquinone in hepatocytes isolated from rats was studied. This compound was chemically inert in the reaction system used. However, in buffer solution containing isolated hepatocytes, it was gradually converted i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2d6588306512fb544f933598a41cc9
https://doi.org/10.1016/0006-291x(83)91470-5
https://doi.org/10.1016/0006-291x(83)91470-5