Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kanwal, Minhas"'
Publikováno v:
Journal of Oncology, Vol 2012 (2012)
Journal of Oncology
Journal of Oncology
Antiangiogenic therapy is theoretically a promising anticancer approach but does not always produce significant tumor control. Combinations of antiangiogenic therapies are therefore being investigated as strategies to enhance clinical benefit. Common
Publikováno v:
International Journal of Experimental Pathology. 92:106-116
It is well established that solid tumour growth beyond a size of 1–2 mm in diameter is angiogenesis dependent, based on the observation that human microscopic, non-angiogenic, tumours can persist in a state of dormancy for long periods of time (Fol
Autor:
Brenda L. Coomber, Una Adamcic, Siranoush Shahrzad, Sirin A. Adham, Claire L. Plumb, Kanwal Minhas
Publikováno v:
The American Journal of Pathology. 175:1662-1674
Dysregulation or mislocalization of cell adhesion molecules and their regulators, such as E-cadherin, beta-catenin, and alpha-catenin, usually correlates with loss of polarity, dedifferentiation, invasive tumor growth, and metastasis. A subpopulation
Autor:
Janice D. Greenwood, Brenda L. Coomber, Daniel J. Dumont, Courtney M. Stone, Kanwal Minhas, Jason J.A. Marriott, Kelly E. Fathers
Publikováno v:
The American Journal of Pathology. 167:1753-1762
To evaluate the expression of the Tie2/Tek tyrosine kinase receptor in tumor blood vessels, we examined Tie2lacZ + /RAG1 − mice. There was considerable heterogeneity (Tie2-negative, Tie2-positive, or Tie2-composite blood vessels) in subcutaneous xe
Publikováno v:
Infection and Immunity. 72:4393-4400
Mannheimia haemolyticainfection of the lower respiratory tract of cattle results in a bronchofibrinous pneumonia characterized by massive cellular influx and lung tissue remodeling and scarring. Since altered levels of gelatinases and their inhibitor
Publikováno v:
The Anatomical Record. 266:69-80
Pulmonary intravascular macrophages (PIMs) contain a unique electron-dense globular surface-coat which is sensitive to heparin treatment, halothane anesthesia, and the digestive effect of lipolytic lipase (LPL), suggesting that the coat is predominan
Publikováno v:
Journal of Anatomy. 198:611-624
The pulmonary intravascular macrophages (PIMs) of domestic ungulates are recognised by their specific surface coat, consisting of linearly arranged globules along the external leaf of the plasma membrane. The coat is sensitive to in vitro digestion w
Publikováno v:
International journal of experimental pathology. 92(2)
Transgenic mice are important tools for our study of breast cancer pathobiology. In order to evaluate changes in cell phenotype with breast cancer progression, we examined vascular and progenitor cell characteristics in tumours derived from MMTV-PyVm
Publikováno v:
Cancer letters. 297(1)
We examined the effect of hypoxia on apoptosis of human colorectal cancer (CRC) cells in vitro and in vivo. All cell lines tested were susceptible to hypoxia-induced apoptosis. DCA treatment caused significant apoptosis under normoxia in SW480 and Ca
Publikováno v:
The Anatomical Record. 234:223-239
We previously reported that the pulmonary intravascular macrophages (PIMs) of sheep, goat, and calf lung contained a heparin and a lipolytic lipase sensitive surface coat by using tannic acid as a component of paraformaldehyde-glutaraldehyde-based fi