Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Kanury V S Rao"'
Publikováno v:
Molecular Systems Biology, Vol 3, Iss 1, Pp 1-17 (2007)
Abstract We examined responses of the B‐cell antigen receptor‐dependent intracellular signaling network to targeted perturbations induced through siRNA‐mediated depletion of select signaling intermediates. The constituent nodes displayed graded
Externí odkaz:
https://doaj.org/article/2fb81ff6a09b48daa4df6d7c628c79a4
Autor:
Parul Mehrotra, Shilpa V Jamwal, Najmuddin Saquib, Neeraj Sinha, Zaved Siddiqui, Venkatasamy Manivel, Samrat Chatterjee, Kanury V S Rao
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004265 (2014)
The success of Mycobacterium tuberculosis as a pathogen derives from its facile adaptation to the intracellular milieu of human macrophages. To explore this process, we asked whether adaptation also required interference with the metabolic machinery
Externí odkaz:
https://doaj.org/article/0af258e6759c41edb7411f061e5363b5
Autor:
Shilpi Jayaswal, Md Azhar Kamal, Raina Dua, Shashank Gupta, Tanmay Majumdar, Gobardhan Das, Dhiraj Kumar, Kanury V S Rao
Publikováno v:
PLoS Pathogens, Vol 6, Iss 4, p e1000839 (2010)
The stable infection of host macrophages by Mycobacterium tuberculosis (Mtb) involves, and depends on, the attenuation of the diverse microbicidal responses mounted by the host cell. This is primarily achieved through targeted perturbations of the ho
Externí odkaz:
https://doaj.org/article/3240037cfe9c499a8e3f4e5608a5561d
Autor:
Rania Bouzeyen, Saurabh Chugh, Tannu Priya Gosain, Mohamed-Ridha Barbouche, Meriam Haoues, Kanury V. S. Rao, Makram Essafi, Ramandeep Singh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The failure of M. bovis BCG to induce long-term protection has been endowed to its inability to escape the phagolysosome, leading to mild activation of CD8+ mediated T cell response. Induction of apoptosis in host cells plays an important role in pot
Externí odkaz:
https://doaj.org/article/ffaa4ea1e899451aad6a467a6a8a48ab
Autor:
Ankur Gupta, Ganga Sagar, Zaved Siddiqui, Kanury V. S. Rao, Sujata Nayak, Najmuddin Saquib, Rajat Anand
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
We integrated untargeted serum metabolomics using high-resolution mass spectrometry with data analysis using machine learning algorithms to accurately detect early stages of the women specific cancers of breast, endometrium, cervix, and ovary across
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a414cf5a2df9caa6c22b83348f20f89
https://pubmed.ncbi.nlm.nih.gov/35145183
https://pubmed.ncbi.nlm.nih.gov/35145183
Autor:
Tannu Priya Gosain, Ramandeep Singh, Saurabh Chugh, Rania Bouzeyen, Mohamed-Ridha Barbouche, Meriam Haoues, Kanury V S Rao, Makram Essafi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
The failure of M. bovis BCG to induce long-term protection has been endowed to its inability to escape the phagolysosome, leading to mild activation of CD8+ mediated T cell response. Induction of apoptosis in host cells plays an important role in pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2410a6ad728c222543716344d34efd3
https://www.frontiersin.org/articles/10.3389/fimmu.2021.645962/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.645962/full
Autor:
Kanury V. S. Rao, Prasanth R. Nyalapatla, Hiroaki Mitsuya, Hironori Hayashi, Arun K. Ghosh, Debananda Das, Hiromi Aoki-Ogata, David A. Davis, Shin-ichiro Hattori, Haydar Bulut, Manabu Aoki
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
HIV-1 protease inhibitors (PIs), such as darunavir (DRV), are the key component of antiretroviral therapy. However, HIV-1 often acquires resistance to PIs. Here, seven novel PIs were synthesized, by introducing single atom changes such as an exchange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f538916898916206ff82e08ff58f97a9
https://doi.org/10.1038/s41598-020-65993-z
https://doi.org/10.1038/s41598-020-65993-z
Autor:
Satish Kovela, Heather L. Osswald, Manabu Aoki, Arun K. Ghosh, Masayuki Amano, Kanury V. S. Rao, Johnson Agniswamy, Yuan-Fang Wang, Irene T. Weber, Hiroaki Mitsuya, Prasanth R. Nyalapatla, Margherita Brindisi
Publikováno v:
Journal of Medicinal Chemistry. 61:4561-4577
The design, synthesis, and biological evaluation of a new class of HIV-1 protease inhibitors containing stereochemically defined fused tricyclic polyethers as the P2 ligands and a variety of sulfonamide derivatives as the P2′ ligands, are described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca06c578663722668527273bbfc1ad4e
https://doi.org/10.1021/acs.jmedchem.8b00298
https://doi.org/10.1021/acs.jmedchem.8b00298
Publikováno v:
Data in Brief
Data in Brief, Vol 17, Iss, Pp 604-609 (2018)
Data in Brief, Vol 17, Iss, Pp 604-609 (2018)
The Rb protein is a tumor suppressor protein that regulates the key G1S checkpoint consequently blocking the progression of cell cycle into S-phase. Despite its pertinent role in cell cycle regulation, comprehensive information on its interacting par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3798ab93d69dd4be3166402fc88d05f9
http://europepmc.org/articles/PMC5852261
http://europepmc.org/articles/PMC5852261
Autor:
Ravikiran S. Yedidi, Masayuki Amano, Arun K. Ghosh, Hirotomo Nakata, Hiroaki Mitsuya, Kanury V. S. Rao, Pedro Miguel Salcedo-Gómez, Nicole S. Delino
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
We report that GRL-09510, a novel HIV-1 protease inhibitor (PI) containing a newly-generated P2-crown-tetrahydrofuranylurethane (Crwn-THF), a P2′-methoxybenzene, and a sulfonamide isostere, is highly active against laboratory and primary clinical H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd46ec03ebbf385e627102799899521f
http://link.springer.com/article/10.1038/s41598-017-12052-9
http://link.springer.com/article/10.1038/s41598-017-12052-9