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The twisted path of the 3D genome: where does it lead?

Autor: Razin SV; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia. Electronic address: sergey.v.razin@inbox.ru., Kantidze OL; Institute of Gene Biology, Russian Academy of Sciences, Moscow, 119334, Russia. Electronic address: kantidze@gmail.com.

Publikováno v: Trends in biochemical sciences [Trends Biochem Sci] 2022 Sep; Vol. 47 (9), pp. 736-744. Date of Electronic Publication: 2022 May 08.

Suppression of liquid-liquid phase separation by 1,6-hexanediol partially compromises the 3D genome organization in living cells.

Autor: Ulianov SV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Faculty of Biology, Lomonosov Moscow State University, 119992 Moscow, Russia., Velichko AK; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia.; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, 119991 Moscow, Russia., Magnitov MD; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia.; Department of Biological and Medical Physics, Moscow Institute of Physics and Technology (National Research University), 141701 Dolgoprudny, Russia., Luzhin AV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Golov AK; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia., Ovsyannikova N; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia., Kireev II; A.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 119992 Moscow, Russia.; V.I. Kulakov National Medical Research Center for Obstetrics, Gynecology, and Perinatology, 117997 Moscow, Russia., Gavrikov AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Mishin AS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Garaev AK; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia., Tyakht AV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Gavrilov AA; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Kantidze OL; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia., Razin SV; Institute of Gene Biology Russian Academy of Science, 119334 Moscow, Russia.

Publikováno v: Nucleic acids research [Nucleic Acids Res] 2021 Oct 11; Vol. 49 (18), pp. 10524-10541.

DNA G-Quadruplexes Contribute to CTCF Recruitment.

Autor: Tikhonova P; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Pavlova I; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia., Isaakova E; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Tsvetkov V; A.V. Topchiev Institute of Petrochemical Synthesis RAS, 119071 Moscow, Russia.; WCRC Russia 'Digital Biodesign and Personalized Healthcare', Sechenov First Moscow State Medical University, 119146 Moscow, Russia., Bogomazova A; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Vedekhina T; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Luzhin AV; Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Sultanov R; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Severov V; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Klimina K; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Kantidze OL; Institute of Gene Biology Russian Academy of Sciences, 119334 Moscow, Russia., Pozmogova G; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Lagarkova M; Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia., Varizhuk A; Moscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 30; Vol. 22 (13). Date of Electronic Publication: 2021 Jun 30.

LASCA: loop and significant contact annotation pipeline.

Autor: Luzhin AV; Institute of Gene Biology Russian Academy of Science, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, Moscow, Russia., Golov AK; Institute of Gene Biology Russian Academy of Science, Moscow, Russia., Gavrilov AA; Institute of Gene Biology Russian Academy of Science, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, Moscow, Russia., Velichko AK; Institute of Gene Biology Russian Academy of Science, Moscow, Russia.; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology Russian Academy of Sciences, Moscow, Russia.; Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russia., Ulianov SV; Institute of Gene Biology Russian Academy of Science, Moscow, Russia., Razin SV; Institute of Gene Biology Russian Academy of Science, Moscow, Russia. sergey.v.razin@usa.net., Kantidze OL; Institute of Gene Biology Russian Academy of Science, Moscow, Russia. kantidze@gmail.com.

Publikováno v: Scientific reports [Sci Rep] 2021 Mar 18; Vol. 11 (1), pp. 6361. Date of Electronic Publication: 2021 Mar 18.