Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kanta Mikami"'
Autor:
Koichi Tanaka, Mohammed E. Choudhury, Satoshi Kikuchi, Ikuko Takeda, Kensuke Umakoshi, Noriyuki Miyaue, Kanta Mikami, Ayane Takenaga, Harumichi Yagi, Rintaro Shinabe, Hironori Matsumoto, Hajime Yano, Masahiro Nagai, Jun Takeba, Junya Tanaka
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109587- (2024)
Summary: In this study, a murine sepsis model was developed using the cecum ligation and puncture (CLP) technique. The expression of the proinflammatory cytokines tumor necrosis factor alpha (TNF-α) and interleukin-1β (IL-1β) in the brain increase
Externí odkaz:
https://doaj.org/article/7d116aa1574c4a7fb90662063b090b33
Autor:
Satoru Taguchi, Mohammed E. Choudhury, Kanta Mikami, Ryo Utsunomiya, Hajime Yano, Junya Tanaka
Publikováno v:
Annals of Rehabilitation Medicine, Vol 46, Iss 6, Pp 320-328 (2022)
Objective To determine the appropriate time points to start regular exercise which could reduce age-related anxiety and impaired social behavior. Methods For this study, 8-week-old male Wistar rats were divided into three groups: no exercise (NoEX),
Externí odkaz:
https://doaj.org/article/96ef89218aff4846bc742bc10e4ce887
Autor:
Shirabe Matsumoto, Mohammed E. Choudhury, Haruna Takeda, Arisa Sato, Nanako Kihara, Kanta Mikami, Akihiro Inoue, Hajime Yano, Hideaki Watanabe, Yoshiaki Kumon, Takeharu Kunieda, Junya Tanaka
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Ischemic stroke is a leading cause of mortality and permanent disability. Chronic stroke lesions increase gradually due to the secondary neuroinflammation that occurs following acute ischemic neuronal degeneration. In this study, the ameliorating eff
Externí odkaz:
https://doaj.org/article/4ecd7bcc070346809c94f2c50fc1e634
Autor:
Mohammed E. Choudhury, Saya Ozaki, Noriyuki Miyaue, Taisei Matsuura, Kanta Mikami, Afsana Islam, Madoka Kubo, Rina Ando, Hajime Yano, Takeharu Kunieda, Masahiro Nagai, Junya Tanaka
Publikováno v:
Brain Sciences, Vol 13, Iss 1, p 55 (2022)
Activated microglia potentially cause neurodegeneration in Parkinson’s disease (PD). Matrix metalloproteinase (MMP)-9 plays a crucial role in the pathogenesis of PD, but the modulator of microglial release of MMP-9 remains obscure. Given the modula
Externí odkaz:
https://doaj.org/article/39b91d4a0d7b4387b7e6242fa12d6833
Autor:
Ryo Utsunomiya, Kanta Mikami, Tomomi Doi, Mohammed E. Choudhury, Toshihiro Jogamoto, Naohito Tokunaga, Eiichi Ishii, Mariko Eguchi, Hajime Yano, Junya Tanaka
Publikováno v:
Cells, Vol 11, Iss 22, p 3649 (2022)
In addition to genetic factors, environmental factors play a role in the pathogenesis of attention deficit/hyperactivity disorder (ADHD). This study used Lister hooded rats (LHRs) as ADHD model animals to evaluate the effects of environmental factors
Externí odkaz:
https://doaj.org/article/12ea81b0b95f4879be9a5fba735fe764
Publikováno v:
Cancers, Vol 14, Iss 19, p 4890 (2022)
CLICs are the dimorphic protein present in both soluble and membrane fractions. As an integral membrane protein, CLICs potentially possess ion channel activity. However, it is not fully clarified what kinds of roles CLICs play in physiological and pa
Externí odkaz:
https://doaj.org/article/0da6ff26f9564dd580f09e1c1a3aa467
Autor:
Yuki Nishikawa, Mohammed E. Choudhury, Kanta Mikami, Taisei Matsuura, Madoka Kubo, Masahiro Nagai, Satoru Yamagishi, Tomomi Doi, Manami Hisai, Haruto Yamamoto, Chisato Yajima, Tasuku Nishihara, Naoki Abe, Hajime Yano, Toshihiro Yorozuya, Junya Tanaka
Publikováno v:
Neurochemistry International. 163:105479
Microglia play a central role in neuroinflammatory processes by releasing proinflammatory mediators. This process is tightly regulated along with neuronal activities, and neurotransmitters may link neuronal activities to the microglia. In this study,
Autor:
Mohammed E, Choudhury, Kanta, Mikami, Yuiko, Nakanishi, Taisei, Matsuura, Ryo, Utsunomiya, Hajime, Yano, Madoka, Kubo, Rina, Ando, Jun, Iwanami, Masakatsu, Yamashita, Masahiro, Nagai, Junya, Tanaka
Publikováno v:
Journal of Neuroimmunology. 363:577794
Myeloid differentiation primary response gene 88 (MyD88) is essential for microglial activation. Despite the significant role of microglia in regulating sleep homeostasis, the contribution of MyD88 to sleep is yet to be determined. To address this, w