Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kansas Sparks"'
Autor:
Amanda Hott, Amanda Rutter, Kansas Sparks, Debora Casandra, Geocel-Grace Castanares, Dennis E. Kyle, Lindsay Morton
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:3156-3167
Artemisinin derivatives are used in combination with other antimalarial drugs for treatment of multidrug-resistant malaria worldwide. Clinical resistance to artemisinin recently emerged in southeast Asia, yet in vitro phenotypes for discerning mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810e6393a04524408043126433a2284b
https://doi.org/10.1128/aac.00197-15
https://doi.org/10.1128/aac.00197-15
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:302-314
Emergence of artemisinin resistance in Cambodia highlights the importance of characterizing resistance to this class of drugs. Previously, intermediate levels of resistance in Plasmodium falciparum were generated in vitro for artelinic acid (AL) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168e83d2e7b5534d5375ff4d4d857769
https://doi.org/10.1128/aac.05540-11
https://doi.org/10.1128/aac.05540-11
Publikováno v:
The Journal of antimicrobial chemotherapy. 70(10)
Objectives Drug resistance confers a fitness advantage to parasites exposed to frequent drug pressure, yet these mutations also may incur a fitness cost. We assessed fitness advantages and costs of artemisinin resistance in Plasmodium falciparum in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b00ed7de60e08834014a1a9e08059cf2
https://pubmed.ncbi.nlm.nih.gov/26203183
https://pubmed.ncbi.nlm.nih.gov/26203183
Publikováno v:
Malaria Journal
Materials and methods In this study we culture adapted and characterized a series of P. falciparum clones from Cambodia; these included parasites from cases with reduced parasite clearance rates in vivo. In vitro artemisinin resistance phenotypes wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958a31665427756e1a9bdf73fe56ee1d
https://doi.org/10.1186/1475-2875-13-s1-p43
https://doi.org/10.1186/1475-2875-13-s1-p43
Publikováno v:
Journal of clinical microbiology. 49(12)
A novel multitarget real-time PCR (RT-PCR) assay for the rapid identification of Bordetella pertussis , B. parapertussis , and B. holmesii was developed using multicopy insertion sequences (ISs) in combination with the pertussis toxin subunit S1 ( pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb4f23951fe76f9b52796c2a4b4880c
https://pubmed.ncbi.nlm.nih.gov/21940464
https://pubmed.ncbi.nlm.nih.gov/21940464