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Bromo- and Extra-Terminal Domain Inhibitors Induce Mitochondrial Stress in Pancreatic Ductal Adenocarcinoma.

Autor: Rana M; Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Kansal RG; Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Bisunke B; Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Transplant Research Institute, James D. Eason Transplant Institute, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Fang J; St. Jude Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee., Shibata D; Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Bajwa A; Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Transplant Research Institute, James D. Eason Transplant Institute, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Department of Genetics, Genomics, and Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Department of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Yang J; Transplant Research Institute, James D. Eason Transplant Institute, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; St. Jude Graduate School of Biomedical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.; Department of Genetics, Genomics, and Informatics, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Comprehensive Cancer Center, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee., Glazer ES; Department of Surgery, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.; Center for Cancer Research, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2023 Aug 01; Vol. 22 (8), pp. 936-946.