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RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain
Autor:
Kim, Jung In, Nakahama, Taisuke, Yamasaki, Ryuichiro, Costa Cruz, Pedro Henrique, Vongpipatana, Tuangtong, Inoue, Maal, Kanou, Nao, Xing, Yanfang, Todo, Hiroyuki, Shibuya, Toshiharu, Kato, Yuki, Kawahara, Yukio
Publikováno v:
PLoS Genetics
Adenosine deaminase acting on RNA 1 (ADAR1), an enzyme responsible for adenosine-to-inosine RNA editing, is composed of two isoforms: nuclear p110 and cytoplasmic p150. Deletion of Adar1 or Adar1 p150 genes in mice results in embryonic lethality with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b057fe7c12c8a7ac0694af9e76d8093c
http://europepmc.org/articles/PMC8118328
http://europepmc.org/articles/PMC8118328
