Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Kannankeril P"'
Autor:
Allison J. Weatherly, MD, Cassandra A. Johnson, MS, Dandan Liu, PhD, Prince J. Kannankeril, MD, MSCI, Heidi A.B. Smith, MD, MSCI, FAAP, Kristina A. Betters, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1119 (2024)
OBJECTIVE:. ICU delirium commonly complicates critical illness associated with factors such as cardiopulmonary bypass (CPB) time and the requirement of mechanical ventilation (MV). Recent reports associate hyperoxia with poorer outcomes in critically
Externí odkaz:
https://doaj.org/article/a3e492835f584a11830f0227d8cc3d18
Autor:
Nejumal Kannankeril Khalid, Maud Le Calvez, Mélanie Lemire, Quoc Tuc Dinh, Justine Fontaine, Stéphane Lair, Sébastien Sauvé
Publikováno v:
Frontiers in Environmental Chemistry, Vol 5 (2024)
Limited data are available for the occurrence of more recent per and polyfluorinated alkyl substances (PFAS) in marine mammals, especially from the St. Lawrence Estuary and Gulf. This study investigates the occurrence of PFAS in liver and muscle tiss
Externí odkaz:
https://doaj.org/article/95db25d86029490da8a910ea986d55f1
Autor:
Megan J. Puckelwartz, Lorenzo L. Pesce, Edgar J. Hernandez, Gregory Webster, Lisa M. Dellefave-Castillo, Mark W. Russell, Sarah S. Geisler, Samuel D. Kearns, Felix Karthik, Susan P. Etheridge, Tanner O. Monroe, Tess D. Pottinger, Prince J. Kannankeril, M. Benjamin Shoemaker, Darlene Fountain, Dan M. Roden, Meghan Faulkner, Heather M. MacLeod, Kristin M. Burns, Mark Yandell, Martin Tristani-Firouzi, Alfred L. George, Elizabeth M. McNally
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Sudden unexpected death in children is a tragic event. Understanding the genetics of sudden death in the young (SDY) enables family counseling and cascade screening. The objective of this study was to characterize genetic variatio
Externí odkaz:
https://doaj.org/article/754c31b062b14f8fb5738e1f18f62142
Autor:
Eric L. Eisenstein, Kevin D. Hill, Nancy Wood, Jerry L. Kirchner, Kevin J. Anstrom, Christopher B. Granger, Sunil V. Rao, H. Scott Baldwin, Jeffrey P. Jacobs, Marshall L. Jacobs, Prince J. Kannankeril, Eric M. Graham, Sean M. O'Brien, Jennifer S. Li
Publikováno v:
Contemporary Clinical Trials Communications, Vol 38, Iss , Pp 101257- (2024)
Background: Registry-based trials have the potential to reduce randomized clinical trial (RCT) costs. However, observed cost differences also may be achieved through pragmatic trial designs. A systematic comparison of trial costs across different des
Externí odkaz:
https://doaj.org/article/7912ef2ef50e4a909f9255670edbac5b
Autor:
Morgan L. Shannon, Ayesha Muhammad, Nathan T. James, Michael L. Williams, Joseph Breeyear, Todd Edwards, Jonathan D. Mosley, Leena Choi, Prince Kannankeril, Sara Van Driest
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 9, Pp 1628-1638 (2023)
Abstract Despite complex pathways of drug disposition, clinical pharmacogenetic predictors currently rely on only a few high effect variants. Quantification of the polygenic contribution to variability in drug disposition is necessary to prioritize t
Externí odkaz:
https://doaj.org/article/78760351264f4889bf9ad2b11ae5f4e8
Autor:
Aleksandra Polic, MD, Stacy A.S. Killen, MD, MSCI, Janette F. Strasburger, MD, Prince J. Kannankeril, MD, MSCI, Ronald T. Wakai, PhD, Soha S. Patel, MD, MSPH
Publikováno v:
JACC: Case Reports, Vol 29, Iss 3, Pp 102183- (2024)
A low baseline fetal heart rate at 20 weeks’ gestation was detected in a fetus without cardiac structural anomalies. Fetal echocardiography and magnetocardiography were used to diagnose congenital long QT syndrome. It was confirmed in the neonate,
Externí odkaz:
https://doaj.org/article/354f972781f04be78996603f2c6f53b7
Akademický článek
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Akademický článek
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Autor:
Sudeep D. Sunthankar, Prince J. Kannankeril, Andrea Gaedigk, Andrew E. Radbill, Frank A. Fish, Sara L. Van Driest
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 7, Pp 1787-1795 (2022)
Abstract Propafenone is an antiarrhythmic drug metabolized primarily by cytochrome P450 2D6 (CYP2D6). In adults, propafenone adverse events (AEs) are associated with CYP2D6 poor metabolizer status; however, pediatric data are lacking. Subjects were t
Externí odkaz:
https://doaj.org/article/6026c7e303044f3babf4a37c9394b561
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Atrial fibrillation (AF) is the most common human arrhythmia and is associated with increased risk of stroke, dementia, heart failure, and death. Among several animal models that have been used to investigate the molecular determinants of AF, mouse m
Externí odkaz:
https://doaj.org/article/ef7c31c6489b4e488f970b79020cb8d4