Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kanji Yoshida"'
Publikováno v:
Japanese Journal of Applied Physics. 59:SKKE13
Publikováno v:
Blood. 97:3498-3504
CD100/Sema4D is a 150-kd transmembrane protein that belongs to the semaphorin family. The interaction of CD100 with CD72 is critical for the immune system. In CD100-deficient mice, the production of specific antibodies against T-cell-dependent antige
Autor:
Hitoshi Kikutani, Wei Shi, Atsushi Kumanogoh, Jane R. Parnes, Xiaosong Wang, Teruhito Yasui, Kazunori Yukawa, Chie Watanabe, Junji Uchida, Masaru Okabe, Kanji Yoshida, Masahito Ikawa
Publikováno v:
Immunity. 13(5):633-642
The class IV semaphorin CD100/Sema4D differentially utilizes two distinct receptors: plexin-B1 in nonlymphoid tissues, such as brain and kidney, and CD72 in lymphoid tissues. We have generated CD100-deficient mice and demonstrated that they have func
Autor:
Haruhiko Hirata, Teruhito Yasui, Junji Uchida, Ihn-Sook Lee, Makoto Matsumoto, Hidetaka Yakura, Chin Pan, Hitoshi Kikutani, Jane R. Parnes, Hiroshi Araki, Xiaosong Wang, Wei Shi, Chie Watanabe, Kota Iwahori, Kanji Yoshida, Atsushi Kumanogoh
Publikováno v:
Immunity. 13(5):621-631
We have identified the lymphocyte semaphorin CD100/Sema4D as a CD40-inducible molecule by subtractive cDNA cloning. CD100 stimulation significantly enhanced the effects of CD40 on B cell responses. Administration of soluble CD100 markedly accelerated
Autor:
Werner Müller, Maries van den Broek, Tetsuya Taga, Ulrich A. K. Betz, Tadamitsu Kishimoto, Klaus Rajewsky, Wilhelm Bloch, Klaus Addicks, Kanji Yoshida
Publikováno v:
The Journal of Experimental Medicine
The pleiotrophic but overlapping functions of the cytokine family that includes interleukin (IL)-6, IL-11, leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and cardiotrophin 1 are mediated by the cytokine receptor subunit gp130
Autor:
Hiromichi Norimatsu, Tatsuo Suda, Toshitaka Nakamura, Kojiro Kawasaki, Kanji Yoshida, Satoshi Yokose, Tadamitsu Kishimoto, Takahito Yuasa, Yoshio Kaji, Hiroko Kataoka, Tetsuya Taga, Yu-Hao Gao, Akira Yamaguchi
Publikováno v:
Endocrinology. 138:4959-4965
Interleukin (IL)-6, IL-11, leukemia inhibitory factor, and oncostatin M similarly induce osteoclast formation in cocultures of osteoblastic cells and bone marrow cells. These cytokines share a common signal transducer, gp130, which forms a receptor c
Autor:
Satoko Marukawa, Ihn-Sook Lee, Tadamitsu Kishimoto, Atsushi Kumanogoh, Teruhito Yasui, Kanji Yoshida, Takayuki Kumanogoh, Hisao Hirota, Tetsuya Taga, Kenji Yoshida
Publikováno v:
Proceedings of the National Academy of Sciences. 94:2478-2482
gp130 is a common signal-transducing receptor component for the interleukin 6 family of cytokines functioning in, for example, immune, hematopoietic, and nervous systems. In this study, to investigate the physiological functions of gp130 and to deter
Autor:
Ryoichi Yoshimura, Tadamitsu Kishimoto, Hiroshi Kiyama, Tetsuya Taga, Dai Watanabe, M. Khalil, Kanji Yoshida
Publikováno v:
European Journal of Neuroscience. 8:1630-1640
The localization of gp130, the signal transducing receptor component used in common for interleukin (IL)-6, IL-11, ciliary neurotrophic factor (CNTF), LIF and OSM, in the rat brain was demonstrated by immunohistochemistry using an antibody specific t
Publikováno v:
Trends in Cardiovascular Medicine. 6:109-115
gp130 was initially identified as a signal-transducing receptor component that associates with the interleukin 6 receptor (IL-6R) when the receptor is occupied by interleukin 6 (IL-6). It has been revealed that the receptor complexes for IL-6, IL-11,
Autor:
Chisato Mori, Kohei Shiota, Kazuhiko Tanaka, Tetsuya Taga, Tatsutoshi Nakahata, Moritoshi Hirata, Tomoko Hirabayashi, Wei-Zhong Wang, Mikiyoshi Saito, Yoshihiro Yoneda, Nobuaki Yoshida, Hiroshi Fujiwara, Sachiko Suematsu, Tamotsu Yamagami, Takashi Tanaka, Tadamitsu Kishimoto, Atsushi Kumanogoh, Kanji Yoshida
Publikováno v:
Proceedings of the National Academy of Sciences. 93:407-411
gp130 is a ubiquitously expressed signal-transducing receptor component shared by interleukin 6, interleukin 11, leukemia inhibitory factor, oncostatin M, ciliary neurotrophic factor, and cardiotrophin 1. To investigate physiological roles of gp130 a