Zobrazeno 1 - 10 of 25 pro vyhledávání: '"Kanji Kobayashi"'
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Clinical Factors and Biomarkers Which Affect a New Universal Grading System for Ovarian Epithelial Carcinoma
Autor: Yoshihiro Nishioka, Ryuichi Kudo, Kanji Kobayashi, Shinichi Ishioka, Satoru Sagae, Masaki Sugimura
Publikováno v: Journal of Obstetrics and Gynaecology Research. 27:313-318
Objective: To detect clinical factors and biomarkers which affect a new grading system for ovarian epithelial cancer that was proposed by Shimizu et al. and to analyze the impact of those factors on malignant behaviors of the tumor. Methods: Review a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b0d64d3cdb5b5e0d2b5479c02f9ee0
https://doi.org/10.1111/j.1447-0756.2001.tb01278.x
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4
A Single Nucleotide Polymorphism in the Matrix Metalloproteinase-1 Promoter in Endometrial Carcinomas
Autor: Yoshihiro Nishioka, Ryuichi Kudo, Kanji Kobayashi, Satoru Sagae, Shinichi Ishioka, Akira Nishikawa, Takeo Minaguchi, Mieko Matsushima, Yasunobu Kanamori, Takashi Tokino, Yusuke Nakamura
Publikováno v: Japanese Journal of Cancer Research : Gann
Recent studies demonstrated that a single guanine insertion polymorphism in a matrix metalloprotease-1 promoter created an Ets binding site and affected the elevation of the transcriptional level of matrix metalloproteinase-1 (MMP-1). Furthermore, in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c338009195e15c0defa9782a65a439be
https://doi.org/10.1111/j.1349-7006.2000.tb00989.x
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5
Mutation of theSRCGene in Endometrial Carcinoma
Autor: Yoshihiro Nishioka, Katsuhiko Terasawa, Satoru Sagae, Masaki Sugimura, Shinichi Ishioka, Ryuichi Kudo, Kanji Kobayashi, Takashi Tokino
Publikováno v: Japanese Journal of Cancer Research : Gann
Recently, an activating mutation of the SRC gene has been implicated in about one-tenth of advanced colon cancers. The SRC 531 mutation results in truncation of SRC directly C-terminal to the regulatory Tyr 530 and appears to activate the Tyr 530. To
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77fe6547d5b4dc098cb9f677095bc5d
https://doi.org/10.1111/j.1349-7006.2000.tb00958.x
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6
Genetic analysis of familial and multiple malignancies of endometrial cancer
Autor: Yoshihiro Nishioka, Masaki Sugimura, Ryuichi Kudo, Kanji Kobayashi, T. Takeda, Satoru Sagae
Publikováno v: International Journal of Gynecology & Obstetrics. 66:149-153
The presence of the positive replication errors (RER) phenotype in familial and multiple primary malignancies of endometrial cancer, and its association with a poor prognosis was examined. We analyzed 40 endometrial cancers for RER. Eight endometrial
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ec5a264b57b01b647e94f42251a1d7
https://doi.org/10.1016/s0020-7292(99)00066-1
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7
Mutational Analysis of β-CateninGene in Japanese Ovarian Carcinomas: Frequent Mutations in Endometrioid Carcinomas
Autor: Masaki Sugimura, Ryuichi Kudo, Kanji Kobayashi, Masami Nagata, Shinichi Ishioka, Satoru Sagae, Yoshihiro Nishioka, Takashi Tokino, Katsuhiko Terasawa
Publikováno v: Japanese Journal of Cancer Research : Gann
To investigate the contribution of the beta-catenin gene to the development of ovarian carcinomas, mutational analysis of exon 3 of the beta-catenin gene was conducted. We analyzed 61 primary ovarian carcinomas, consisting of 49 non-endometrioid-type
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7288a45f50ac50fd776be06f42148a42
https://doi.org/10.1111/j.1349-7006.1999.tb00777.x
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8
Mutations in the BRCA1 gene in Japanese breast cancer patients
Autor: Yoshio Miki, Kanji Kobayashi, Mitsuru Emi, Masataka Yoshimoto, Toyomasa Katagiri, Fujio Kasumi, Mark H. Skolnick, Yusuke Nakamura, Takuji Iwase, Isao Ito
Publikováno v: Human Mutation. 7:334-339
Predisposing germline mutations in the BRCA1 gene were identified recently in families with 17q-linked breast and ovarian cancers. Using single-strand conformation polymorphism (SSCP) analysis, we examined primary breast cancers for mutations in codi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec9d4a8a5341bf29735af22486a92238
https://doi.org/10.1002/(sici)1098-1004(1996)7:4<334::aid-humu7>3.0.co
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9
Microsatellite instability in endometrial carcinomas: Frequent replication errors in tumors of early onset and/or of poorly differentiated type
Autor: Sumiko Koi, Ryuichi Kudo, Hiroko Saito, Yusuke Nakamura, Kanji Kobayashi, Satoru Sagae
Publikováno v: Genes, Chromosomes and Cancer. 14:128-132
Endometrial and ovarian carcinomas are common among women belonging to hereditary nonpolyposis colorectal carcinoma (HNPCC) families; tumors developing in them are characterized by genetic instability due to an inherited dysfunction of the DNA-mismat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e1193a5c175c6bddb939e0b09214a5
https://doi.org/10.1002/gcc.2870140207
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10
Mutation analysis of the BRCA1 gene in 76 Japanese ovarian cancer patients: four germline mutations, but no evidence of somatic mutation
Autor: Mitsuru Emi, Junko Saito, Kaoru Suzumori, Hiroko Saito, Yusuke Nakamura, Mieko Matsushima, Kanji Kobayashi
Publikováno v: Human Molecular Genetics. 4:1953-1956
To investigate the putative role of BRCA1, a gene involved in hereditary breast and ovarian cancer, in sporadic ovarian tumors among Japanese women, we examined 76 unselected primary ovarian cancers for mutations in the coding region of BRCA1 using t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48a6b0d1f01a901b0d54b814c82e5d8
https://doi.org/10.1093/hmg/4.10.1953
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