Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kaniz F. Urmi"'
Autor:
Adrian P. Campbell, Junli Chen, Michael Keem, Cameron Ding-Farington, Karmen Xu, Renate Griffith, Kaniz F. Urmi, Erica Leonar, Angela M. Finch
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO4-11
Publikováno v:
Journal of Molecular Graphics and Modelling. 76:488-503
G protein-coupled receptors (GPCRs) are important targets for development of drugs for the treatment of many diseases. However, crystal structures are available for only a small fraction of these membrane bound proteins. Accurate homology models will
Autor:
Renate Griffith, Junli Chen, Kaniz F. Urmi, Laurence P. G. Wakelin, Angela M. Finch, William A. Denny, Adrian P. Campbell
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:5910-5916
A series of ring-substituted ethyl- and heptyl-linked 4-aminoquinoline dimers were synthesized and evaluated for their affinities at the 3 human α(1)-adrenoceptor (α(1)-AR) subtypes and the human serotonin 5-HT(1A)-receptor (5-HT(1A)-R). We find th