Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kanishka Basnayake"'
Autor:
Kanishka Basnayake, David Mazaud, Alexis Bemelmans, Nathalie Rouach, Eduard Korkotian, David Holcman
Publikováno v:
PLoS Biology, Vol 20, Iss 5, p e3001663 (2022)
[This corrects the article DOI: 10.1371/journal.pbio.2006202.].
Externí odkaz:
https://doaj.org/article/3ed1809f336446fbadd96910dd463e0d
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12321 (2022)
While neuronal mitochondria have been studied extensively in their role in health and disease, the rules that govern calcium regulation in mitochondria remain somewhat vague. In the present study using cultured rat hippocampal neurons transfected wit
Externí odkaz:
https://doaj.org/article/202cab85df4647738d127f49c4f7694f
Autor:
Kanishka Basnayake, David Mazaud, Alexis Bemelmans, Nathalie Rouach, Eduard Korkotian, David Holcman
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e2006202 (2019)
Fast calcium transients (
Externí odkaz:
https://doaj.org/article/7111061f3b914fb3b29676d4e72a118d
Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines
Autor:
David Mazaud, Alexis Bemelmans, Lilia Kushnireva, David Holcman, Kanishka Basnayake, Nathalie Rouach, Eduard Korkotian
Publikováno v:
Science Advances
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (38), ⟨10.1126/sciadv.abh1376⟩
Dendritic spines are critical components of neuronal synapses as they receive and transform synaptic inputs into a succession of calcium-regulated biochemical events. The spine apparatus (SA), an extension of smooth endoplasmic reticulum, regulates s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3335daeaa50771d97c5333c970ab0eab
Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines
Autor:
Kanishka Basnayake, David Holcman
We present here the simulation codes associated with publication [1] written in Python and Mathematica. The simulations concern calcium dynamics in dendritic spines, where each ion motion is modeled as Brownian. Spines have a geometry of a spherical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::c9c35f3139625d1380c45df5a96d225e
https://zenodo.org/record/5547895
https://zenodo.org/record/5547895
Nanoscale molecular architecture controls calcium diffusion and ER replenishment in dendritic spines
Autor:
Alexis Bemelmans, Kanishka Basnayake, David Mazaud, Lilia Kushnireva, Eduard Korkotian, David Holcman, Nathalie Rouach
Dendritic spines are critical components of the neuronal synapse as they receive and transform the synaptic input into a succession of biochemical events regulated by calcium signaling. The spine apparatus (SA), an extension of smooth endoplasmic ret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7757cd7e0d6fd297e11448ef941f49c6
https://doi.org/10.1101/2021.06.08.447402
https://doi.org/10.1101/2021.06.08.447402
Publikováno v:
Physics of Life Reviews. 28:52-79
The paradigm of chemical activation rates in cellular biology has been shifted from the mean arrival time of a single particle to the mean of the first among many particles to arrive at a small activation site. The activation rate is set by extremely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d318f5d8554a52364c911e4ea5fae132
https://doi.org/10.1016/j.plrev.2019.01.001
https://doi.org/10.1016/j.plrev.2019.01.001
Autor:
David Holcman, Kanishka Basnayake
Publikováno v:
Physics of Life Reviews. 28:96-99
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eab090cb386dbc269d2303456287275a
https://doi.org/10.1016/j.plrev.2019.03.017
https://doi.org/10.1016/j.plrev.2019.03.017
Publikováno v:
Physics Letters A. 382:3449-3454
What are the paths associated with the fastest Brownian particles that reach a narrow window located on the boundary of a microdomain? Although the distribution of the fastest arrival times has been well studied in dimension 1, much less is known in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ad5c75242e4b54a50bf6ebcd46b30c3
https://doi.org/10.1016/j.physleta.2018.09.040
https://doi.org/10.1016/j.physleta.2018.09.040
Autor:
Kanishka Basnayake, David Holcman
General description: The first ones among N identical and independently distributed (i.i.d.) Brownian trajectories that arrives to a small target have timescales that are much faster than the average arrival time of a single particle [1]. As introduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf1504750155e11a79ecf67f2197f27