Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kanishk Jain"'
Discovering individual-specific gait signatures from data-driven models of neuromechanical dynamics.
Autor:
Taniel S Winner, Michael C Rosenberg, Kanishk Jain, Trisha M Kesar, Lena H Ting, Gordon J Berman
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011556 (2023)
Locomotion results from the interactions of highly nonlinear neural and biomechanical dynamics. Accordingly, understanding gait dynamics across behavioral conditions and individuals based on detailed modeling of the underlying neuromechanical system
Externí odkaz:
https://doaj.org/article/1334012e51f4454280f4d4d1a810f0bf
Autor:
Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas L Young, Michael-Christopher Keogh, Brian D Strahl
Publikováno v:
eLife, Vol 12 (2023)
In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini availability to the epigenetic machinery. Notably, H3 tail acetylat
Externí odkaz:
https://doaj.org/article/4578fc571e78426c9ad347f2e09aa9c9
Autor:
Kanishk Jain, Caroline S. Fraser, Matthew R. Marunde, Madison M. Parker, Cari Sagum, Jonathan M. Burg, Nathan Hall, Irina K. Popova, Keli L. Rodriguez, Anup Vaidya, Krzysztof Krajewski, Michael-Christopher Keogh, Mark T. Bedford, Brian D. Strahl
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-11 (2020)
Abstract Background Plant homeodomain (PHD) fingers are central “readers” of histone post-translational modifications (PTMs) with > 100 PHD finger-containing proteins encoded by the human genome. Many of the PHDs studied to date bind to unmodifie
Externí odkaz:
https://doaj.org/article/42e1fad0bbb845c0b5d819ca89ab4149
Autor:
Kristin Kovach, Megan Davis-Fields, Yasuhiko Irie, Kanishk Jain, Shashvat Doorwar, Katherine Vuong, Numa Dhamani, Kishore Mohanty, Ahmed Touhami, Vernita D Gordon
Publikováno v:
npj Biofilms and Microbiomes, Vol 3, Iss 1, Pp 1-9 (2017)
Evolution: Toughening up biofilms in lungs Bacteria in lungs of people with cystic fibrosis can evolve through decades to build a tough biofilm that resists the body’s defences. Vernita Gordon and colleagues at the University of Texas, with co-work
Externí odkaz:
https://doaj.org/article/114d584f35b8491a97c9e4fd5cfa9a74
Publikováno v:
INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH. :34-35
Tubulointerstitial nephritis (TIN) is the main renal involvement associated with primary Sjögren syndrome (pSS). TIN can manifest as distal renal tubular acidosis (RTA), nephrogenic diabetes insipidus, proximal tubular dysfunction, and others. We pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01bbabec673ba653201f885e68e0b082
https://doi.org/10.36106/ijsr/0621862
https://doi.org/10.36106/ijsr/0621862
Autor:
Xijuan Liu, Jun Wang, Joshua A. Boyer, Weida Gong, Shuai Zhao, Ling Xie, Qiong Wu, Cheng Zhang, Kanishk Jain, Yiran Guo, Javier Rodriguez, Mingjie Li, Hidetaka Uryu, Chengheng Liao, Lianxin Hu, Jin Zhou, Xiaobing Shi, Yi-Hsuan Tsai, Qin Yan, Weibo Luo, Xian Chen, Brian D. Strahl, Alex von Kriegsheim, Qi Zhang, Gang Greg Wang, Albert S. Baldwin, Qing Zhang
Publikováno v:
Liu, X, Wang, J, Boyer, J A, Gong, W, Zhao, S, Xie, L, Wu, Q, Zhang, C, Jain, K, Guo, Y, Rodriguez, J, Li, M, Uryu, H, Liao, C, Hu, L, Zhou, J, Shi, X, Tsai, Y, Yan, Q, Luo, W, Chen, X, Strahl, B D, Von Kriegsheim, A, Zhang, Q, Wang, G G, Baldwin, A S & Zhang, Q 2022, ' Histone H3 proline 16 hydroxylation regulates mammalian gene expression ', Nature Genetics, vol. 54, pp. 1721-1735 . https://doi.org/10.1038/s41588-022-01212-x
Nat Genet
Nat Genet
Histone post-translational modifications (PTMs) are important forregulating various DNA-templated processes. Here, we report theexistence of a histone PTM in mammalian cells, namely histone H3 withhydroxylation of proline at residue 16 (H3P16oh), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aaaecdd9bf4cf8345029bce9bd5f842
https://www.pure.ed.ac.uk/ws/files/307760960/Histone_H3_proline_16_hydroxylation_regulates_mammalian_gene_expression_AAM.pdf
https://www.pure.ed.ac.uk/ws/files/307760960/Histone_H3_proline_16_hydroxylation_regulates_mammalian_gene_expression_AAM.pdf
Autor:
Kanishk Jain, Brian D. Strahl
Publikováno v:
Nature Reviews Molecular Cell Biology. 24:311-311
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ec99e27c8c410d4023670007cced654
https://doi.org/10.1038/s41580-023-00601-2
https://doi.org/10.1038/s41580-023-00601-2
Publikováno v:
Rheumatology. 61
Background/Aims Rheumatoid arthritis is a chronic inflammatory autoimmune condition associated with multi-system involvement, cardiovascular risk, worsening quality of life measures and increased mortality. Analysing registry data helps identify para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a6c27f80d8060df0a1cbac0b2e02eb
https://doi.org/10.1093/rheumatology/keac133.209
https://doi.org/10.1093/rheumatology/keac133.209
Autor:
Kanishk Jain, Matthew R Marunde, Jonathan M Burg, Susan L Gloor, Faith M Joseph, Karl F Poncha, Zachary B Gillespie, Keli L Rodriguez, Irina K Popova, Nathan W Hall, Anup Vaidya, Sarah A Howard, Hailey F Taylor, Laylo Mukhsinova, Ugochi C Onuoha, Emily F Patteson, Spencer W Cooke, Bethany C Taylor, Ellen N Weinzapfel, Marcus A Cheek, Matthew J Meiners, Geoffrey C Fox, Kevin EW Namitz, Martis W Cowles, Krzysztof Krajewski, Zu-Wen Sun, Michael S Cosgrove, Nicolas Young, Michael-C Keogh, Brian D Strahl
In nucleosomes, histone N-terminal tails exist in dynamic equilibrium between free/accessible and collapsed/DNA-bound states. The latter state is expected to impact histone N-termini availability to the epigenetic machinery. Notably, H3 tail acetylat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56293051dfd39cb6a2645e19d0fa20ad
https://doi.org/10.1101/2022.02.28.482307
https://doi.org/10.1101/2022.02.28.482307
Autor:
Kanishk Jain, Anurag Bharadwaj
Publikováno v:
Rheumatology Advances in Practice. 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5c6f59e39a6cb6957a431af287f1594
https://doi.org/10.1093/rap/rkac077
https://doi.org/10.1093/rap/rkac077