Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kanhaiya Lal Kumawat"'
Autor:
V Haridas, Kullampalayam Shanmugam Rajgokul, Sandhya Sadanandan, Tanvi Agrawal, Vats Sharvani, M V S Gopalakrishna, M B Bijesh, Kanhaiya Lal Kumawat, Anirban Basu, Guruprasad R Medigeshi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 1, p e2005 (2013)
Japanese encephalitis virus (JEV) is a major cause of viral encephalitis in South and South-East Asia. Lack of antivirals and non-availability of affordable vaccines in these endemic areas are a major setback in combating JEV and other closely relate
Externí odkaz:
https://doaj.org/article/43e05af414e744a5b3719a5616008a25
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35427 (2012)
Japanese encephalitis (JE), the most common form of viral encephalitis occurs periodically in endemic areas leading to high mortality and neurological deficits in survivors. It is caused by a flavivirus, Japanese encephalitis virus (JEV), which is tr
Externí odkaz:
https://doaj.org/article/ac4d71103a1f466d90b5500c0f1d65a4
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e32270 (2012)
Japanese Encephalitis virus (JEV) is a common cause of acute and epidemic viral encephalitis. JEV infection is associated with microglial activation resulting in the production of pro-inflammatory cytokines including Interleukin-1 β (IL-1β) and Int
Externí odkaz:
https://doaj.org/article/e980ce3bd57a4d4d8dce78671edd1c88
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17225 (2011)
Japanese encephalitis virus (JEV) induces neuroinflammation with typical features of viral encephalitis, including inflammatory cell infiltration, activation of microglia, and neuronal degeneration. The detrimental effects of inflammation on neurogen
Externí odkaz:
https://doaj.org/article/0e986c457d5543b196882797ee09df9a
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e9984 (2010)
BACKGROUND: Benzo[a]pyrene (B[a]P) belongs to a class of polycyclic aromatic hydrocarbons that serve as micropollutants in the environment. B[a]P has been reported as a probable carcinogen in humans. Exposure to B[a]P can take place by ingestion of c
Externí odkaz:
https://doaj.org/article/41ad01ce50ee400fbb954bd858ed4fca
Publikováno v:
Virology. 573:131-140
Japanese Encephalitis Virus (JEV), a member virus of Flaviviridae family causes Japanese encephalitis (JE). JE is a mosquito-borne disease, spread mainly by Culex spp. During JE, dysregulated inflammatory responses play a central role in neuronal dea
Publikováno v:
Science Signaling. 10
Effective recognition of viral components and the subsequent stimulation of the production of type I interferons (IFNs) is crucial for the induction of host antiviral immunity. The failure of the host to efficiently produce type I IFNs in response to
Publikováno v:
NeuroToxicology. 41:143-153
Lead is one of the major pollutants of environment and is highly toxic to the functioning of central nervous system (CNS). The chronic exposure of this heavy metal is debilitating to the functional behavior of an organism. Studies have shown that acu
Interleukin-1β orchestrates underlying inflammatory responses in microglia via Krüppel-like factor 4
Autor:
Malvika Gupta, Anirban Basu, Menaka C. Thounaojam, Deepak Kumar Kaushik, Kanhaiya Lal Kumawat
Publikováno v:
Journal of Neurochemistry. 127:233-244
Microglia are the resident macrophages of the CNS, which secrete several pro- and anti-inflammatory cyto-chemokines including interleukin-1β (IL-1β), in response to pathogenic stimuli. Once secreted, IL-1β binds to IL-1 receptor present on microgl
Publikováno v:
Scientific Reports
Japanese encephalitis virus (JEV) is a plus strand RNA virus, which infects brain. MicroRNAs are regulatory non-coding RNAs which regulate the expression of various genes in cells. Viruses modulate the expression of various microRNAs to suppress anti