Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Kangseok, Lee"'
Autor:
Hanyong Jin, Ji-Hyun Yeom, Eunkyoung Shin, Yoonjie Ha, Haifeng Liu, Daeyoung Kim, Minju Joo, Yong-Hak Kim, Hak Kyun Kim, Minkyung Ryu, Hong-Man Kim, Jeongkyu Kim, Keun P. Kim, Yoonsoo Hahn, Jeehyeon Bae, Kangseok Lee
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Transfer RNA halves (tRHs) have various biological functions. However, the biogenesis of specific 5′-tRHs under certain conditions remains unknown. Here, we report that inositol-requiring enzyme 1α (IRE1α) cleaves the anticodon stem-loop
Externí odkaz:
https://doaj.org/article/b4210d4c73d54d008503e0bd9a448d77
Autor:
Dokyun Na, Do‐Hwan Lim, Jae‐Sang Hong, Hyang‐Mi Lee, Daeahn Cho, Myeong‐Sang Yu, Bilal Shaker, Jun Ren, Bomi Lee, Jae Gwang Song, Yuna Oh, Kyungeun Lee, Kwang‐Seok Oh, Mi Young Lee, Min‐Seok Choi, Han Saem Choi, Yang‐Hee Kim, Jennifer M Bui, Kangseok Lee, Hyung Wook Kim, Young Sik Lee, Jörg Gsponer
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 12, Pp n/a-n/a (2023)
Abstract The accumulation of misfolded and aggregated proteins is a hallmark of neurodegenerative proteinopathies. Although multiple genetic loci have been associated with specific neurodegenerative diseases (NDs), molecular mechanisms that may have
Externí odkaz:
https://doaj.org/article/189ad69333ab48fca215c7cdd4f22dce
Autor:
Minju Joo, Ji-Hyun Yeom, Younkyung Choi, Hyeon Jun, Wooseok Song, Hyun-Lee Kim, Kangseok Lee, Eunkyoung Shin
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1103-1114 (2022)
The ribosome has long been thought to be a homogeneous cellular machine that constitutively and globally synthesises proteins from mRNA. However, recent studies have revealed that ribosomes are highly heterogeneous, dynamic macromolecular complexes w
Externí odkaz:
https://doaj.org/article/bc9983376d3549c493302094575708f2
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0289072 (2023)
Heterogeneity of ribosomal RNA (rRNA) sequences has recently emerged as a mechanism that can lead to subpopulations of specialized ribosomes. Our previous study showed that ribosomes containing highly divergent rRNAs expressed from the rrnI operon (I
Externí odkaz:
https://doaj.org/article/4bd9e7bab64842eab3e9885e1e0e9067
Autor:
Yeseul Choi, Eunji Jeong, Dong-Gi Lee, Jae-Hyung Jin, Yee-Seul So, Seong-Ryong Yu, Kyung-Jo Lee, Yoonjie Ha, Chi-Jan Lin, Ying-Lien Chen, Jun Bae Park, Hyun-Soo Cho, Anna F. Averette, Joseph Heitman, Kyu-Ho Lee, Kangseok Lee, Yong-Sun Bahn
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT The KEOPS (kinase, putative endopeptidase, and other proteins of small size) complex has critical functions in eukaryotes; however, its role in fungal pathogens remains elusive. Herein, we comprehensively analyzed the pathobiological functio
Externí odkaz:
https://doaj.org/article/be58f2538d9840a9b0c563fe73daf2e5
Autor:
Hanyong Jin, Boeun Lee, Yongyang Luo, Yuri Choi, Eui-Hwan Choi, Hong Jin, Kee-Beom Kim, Sang Beom Seo, Yong-Hak Kim, Hyung Ho Lee, Keun Pil Kim, Kangseok Lee, Jeehyeon Bae
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The Ku complex, formed by XRCC5/6 heterodimer, binds to double strand break (DSB) ends, initiating non homologous end joining (NHEJ) and preventing homologous recombination (HR). Here, the authors reveal that FOXL2, a forkhead family transcriptional
Externí odkaz:
https://doaj.org/article/dc3287deb2f54cbfa67a690e448af5a2
Publikováno v:
MSphere; Jan2024, Vol. 9 Issue 1, p1-16, 16p
Autor:
Minho Lee, Minkyung Ryu, Minju Joo, Young-Jin Seo, Jaejin Lee, Hong-Man Kim, Eunkyoung Shin, Ji-Hyun Yeom, Yong-Hak Kim, Jeehyeon Bae, Kangseok Lee
Publikováno v:
PLoS Pathogens, Vol 17, Iss 2, p e1009263 (2021)
Bacteria utilize endoribonuclease-mediated RNA processing and decay to rapidly adapt to environmental changes. Here, we report that the modulation of hns mRNA stability by the endoribonuclease RNase G plays a key role in Salmonella Typhimurium pathog
Externí odkaz:
https://doaj.org/article/072a8c48e9ad45429737aa77332e12c7
Autor:
Jaesung Choi, Jee-Hye Choi, Ho Woon Lee, Dongbeom Seo, Gavaachimed Lkhagvasuren, Jung-Woong Kim, Sang-Beom Seo, Kangseok Lee, Kwang-Ho Lee
Publikováno v:
BMB Reports. 56:120-125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159bb1723e67b5adc184d73dca98440c
https://doi.org/10.5483/bmbrep.2022-0180
https://doi.org/10.5483/bmbrep.2022-0180
Publikováno v:
Journal of Microbiology. 61:211-220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::788e58ab89055297c06dc3e626bbb474
https://doi.org/10.1007/s12275-023-00013-z
https://doi.org/10.1007/s12275-023-00013-z