Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Kangmei Chen"'
Autor:
Jing Bi, Zhihui Wu, Xin Zhang, Taoling Zeng, Wanjun Dai, Ningyuan Qiu, Mingfeng Xu, Yikai Qiao, Lang Ke, Jiayi Zhao, Xinyu Cao, Qi Lin, Xiao Lei Chen, Liping Xie, Zhong Ouyang, Jujiang Guo, Liangkai Zheng, Chao Ma, Shiying Guo, Kangmei Chen, Wei Mo, Guo Fu, Tong-Jin Zhao, Hong-Rui Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor outcome and lacks of approved targeted therapy. Overexpression of epidermal growth factor receptor (EGFR) is found in more than 50% TNBC and is suggested as a drivi
Externí odkaz:
https://doaj.org/article/95842eda3ab14914b484798d0140d8d0
Autor:
Yuanyuan Li, Bingbin Dong, Wei Wu, Jiawei Wang, Hao Jin, Kangmei Chen, Kangling Huang, Songyin Huang, Yandan Yao
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundGrowing evidence supports the modulatory role of human gut microbiome on neoadjuvant chemotherapy (NAC) efficacy. However, the relationships among the gut microbiome, tumor-infiltrating lymphocytes (TILs), and NAC response for breast cancer
Externí odkaz:
https://doaj.org/article/3963c6a9a3b9458faca9eebf43131d9f
Autor:
Kangmei Chen, Weimei Shi, Zhenhui Xin, Huifen Wang, Xilin Zhu, Xiaopan Wu, Zhuo Li, Hui Li, Ying Liu
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77315 (2013)
BACKGROUND: Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese po
Externí odkaz:
https://doaj.org/article/3ca744c7ac2a4b018111116e9221ef24
Autor:
Dakang Xu, Huijuan Yang, David W. Chan, Celia Sze Ling Mak, Michelle X Liu, Kangmei Chen, Karen K. L. Chan, Hextan Y.S. Ngan, Mingo M. H. Yung, Thomas Ho-Yin Leung, Siew Fei Ngu
Publikováno v:
Theranostics
Human growth factor receptor-bound protein-7 (GRB7) is a pivotal mediator involved in receptor tyrosine kinase signaling and governing diverse cellular processes. Aberrant upregulation of GRB7 is frequently associated with the progression of human ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b073c468be879ca535e220ef314779a0
http://europepmc.org/articles/PMC5743558
http://europepmc.org/articles/PMC5743558
Autor:
Xilin Zhu, Pengyin Zhang, Runhua Wang, Jianfeng Xu, Carly Conran, Ying Liu, Deke Jiang, Daru Lu, Xiaopan Wu, Xiao-Pin Ma, Fang Liu, Ji Qian, Zhuo Li, Kangmei Chen, Jingmin Yang, Jia Wu, Li Sun, Long Yu, S. Lilly Zheng
Publikováno v:
Hepatology. 63:1102-1111
Interferon (IFN)-α is a first-line therapy for chronic hepatitis B (CHB) patients but only initiates a response in a minority of patients. A genetic variant, rs7574865 in STAT4, was recently reported to be associated with risk of developing CHB and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4194ed4c5b78292d09b750abdc282d
https://doi.org/10.1002/hep.28423
https://doi.org/10.1002/hep.28423
Autor:
Kangmei Chen, Wenming Li, Kaimin Cai, Yan Bao, Jianjun Cheng, Yunjiang Jiang, Yang Bo, Jarron Roy
Publikováno v:
Biomaterials. 238:119843
The early in vivo diagnosis of infectious disease foci is largely hindered by invasion and concealment of pathogens in host cells, making it difficult for conventional probes to detect and analyze intracellular pathogens. Taking advantage of the exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901e0ef0133370d96e25337de4805b47
https://doi.org/10.1016/j.biomaterials.2020.119843
https://doi.org/10.1016/j.biomaterials.2020.119843
Autor:
Karen K. L. Chan, Thomas Ho-Yin Leung, Stephanie S. Liu, Celia S. L. Mak, Rui Liang, Lynn Hui, Yiming Qin, Hextan Y.S. Ngan, Kai-Fai Lee, Kangmei Chen, Leanne L. Leung, David W. Chan, Mingo M. H. Yung
Publikováno v:
Molecular Cancer
Background: Cancer metastasis is determined by the formation of the metastatic niche and the ability of cancer cells to adapt to microenvironmental stresses. Anoikis resistance is a fundamental feature of metastatic cancer cell survival during metast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70041f5461dd9c6a67b75d670500ed36
https://doi.org/10.1186/s12943-017-0582-2
https://doi.org/10.1186/s12943-017-0582-2
Autor:
Jia Wu, Hui Li, Ying Liu, Zhongping Duan, Xilin Zhu, Sujun Zheng, Xiaopan Wu, Weimei Shi, Zhuo Li, Kangmei Chen
Publikováno v:
Liver International. 34:1560-1565
Background & Aims Our previous study found that rs4845384 in ADAR1 gene to be associated with HBeAg seroconversion. However, the effect of rs4845384 on HBsAg seroclearance is unknown. To assess the relationship between rs4845384 and HBsAg seroclearan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fea67a7ea2f7275294ffef3c1b88a377
https://doi.org/10.1111/liv.12444
https://doi.org/10.1111/liv.12444
Autor:
Huifen Wang, Jia Wu, Zhenhui Xin, Ying Liu, Hui Li, Kangmei Chen, Zhongping Duan, Wei Zhang, Xiaopan Wu, Zhuo Li, Sujun Zheng, Xilin Zhu
Publikováno v:
International Journal of Cancer. 135:61-68
Accumulated evidences indicate that single nucleotide polymorphisms (SNP) are associated with risk of hepatocellular carcinoma (HCC). Activating transcription factor 6 (ATF6) is an important modulator of the unfolded protein response (UPR), which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c008e1be851c730df7feb871d8620cb7
https://doi.org/10.1002/ijc.28649
https://doi.org/10.1002/ijc.28649