Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Kangkai Wang"'
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107443- (2023)
Summary: Several heat shock proteins are implicated in the endogenous cardioprotective mechanisms, but little is known about the role of heat shock protein beta-1 (HSPB1). This study aims to investigate the oxidation state and role of HSPB1 in cardio
Externí odkaz:
https://doaj.org/article/a5ec154835fb4665a77952a75ae567ec
Aberrant HSF1 signaling activation underlies metformin amelioration of myocardial infarction in mice
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 312-328 (2022)
Myocardial infarction (MI) is a cardiovascular disease with high morbidity and mortality. Clinically, rehabilitation after massive MI often has a poor prognosis. Therefore, it is necessary to explore the therapeutic methods of myocardial protection a
Externí odkaz:
https://doaj.org/article/c0d494f102954efeb932cdc9696656a8
Autor:
Xueyan Shi, Tao Li, Yanting Liu, Leijin Yin, Lan Xiao, Liyao Fu, Yaxi Zhu, Huan Chen, Kangkai Wang, Xianzhong Xiao, Huali Zhang, Sichuang Tan, Sipin Tan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As an important transcription factor, heat shock factor 1 (HSF1) plays an endogenous anti-inflammation role in the body and can alleviate multiple organ dysfunction caused by sepsis, which contributes to an uncontrolled inflammatory response. The NLR
Externí odkaz:
https://doaj.org/article/0994e5f805e248ad8ba9330bb02756a8
Autor:
Shahid Khan, Kangkai Wang, Guangzhong Yuan, Mahmood ul Haq, Zhizheng Wu, Muhammad Usman, Chenlu Song, Gaorong Han, Yong Liu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Based on TiO2 as a model system, the sol-gel one step facile method is established to fabricate the macro-porous morphology films on the basis of Marangoni effect. In this proposed mechanism, the binary mixture of hydrophilic CuCl2 and lipop
Externí odkaz:
https://doaj.org/article/4797aef1f47a4486903ab41df6e23afb
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Fibrotic animal models are critical for the pathogenesis investigations and drug explorations in systemic sclerosis (SSc). The bleomycin (BLM)-induced mouse model is the classical and most widely used fibrosis model. However, traditional subcutaneous
Externí odkaz:
https://doaj.org/article/7ddea0c588674f5ab4720b73a7990226
Autor:
Lei Jiang, Hao Wang, Chunli Shi, Ke Liu, Meidong Liu, Nian Wang, Kangkai Wang, Huali Zhang, Guiliang Wang, Xianzhong Xiao
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111653 (2014)
ZNF667/Mipu1, a C2H2-type zinc finger transcription factor, was suggested to play an important role in oxidative stress. However, none of the target genes or potential roles of ZNF667 in cardiomyocytes have been elucidated. Here, we investigated the
Externí odkaz:
https://doaj.org/article/d2f780f3166f42f18cc6fc87bddd55c1
Autor:
Kangkai Wang, Jian Lei, Jiang Zou, Hui Xiao, Anlan Chen, Xiaoliu Liu, Ying Liu, Lei Jiang, Zihui Xiao, Xianzhong Xiao
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82827 (2013)
Mipu1 (myocardial ischemic preconditioning up-regulated protein 1), recently identified in our lab, is a novel zinc-finger transcription factor which is up-regulated during ischemic preconditioning. However, it is not clear what transcription factor
Externí odkaz:
https://doaj.org/article/b00254dbbc374a7ba3c6500644202af4
Autor:
Kangkai Wang, Jingnan Liao, Jinjin Wang, Wei Wu, Hong Zhou, Mingyuan Wang, Chang Tan, Yiming Li
Publikováno v:
Journal of Cellular and Molecular Medicine
Background MicroRNAs (miRNAs) are widely distributed in cells and participate in the regulation of the pathophysiological process of many diseases. As an important part of non‐coding RNA, miRNAs regulate a variety of molecules and signal pathways i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d236c535a7dfef7b4d30d1329e7aba0
http://europepmc.org/articles/PMC8034472
http://europepmc.org/articles/PMC8034472
Publikováno v:
Cancer Gene Therapy
Cervical cancer (CC) is the second most common cancer and the leading cause of cancer mortality in women. Numerous studies have found that the development of CC was associated with multiple genes. However, the mechanisms on gene level are enigmatic,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579503292570dcbe53021908148ff38a
https://doi.org/10.1038/s41417-020-00278-1
https://doi.org/10.1038/s41417-020-00278-1
Autor:
Huali Zhang, Meng Meng, Wenmei Wang, Nian Wang, Huafei Deng, Jiang Zou, Lili Zhu, Heng Ma, Sipin Tan, Xianzhong Xiao, Kangkai Wang, Qin Fei
Publikováno v:
Journal of Molecular and Cellular Cardiology. 145:1-13
Myocardial ischaemia is usually accompanied by inflammatory response which plays a critical role in the myocardial healing and scar formation, while persistent inflammatory response contributes greatly to the myocardial remodeling and consequent hear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc322e501554f6c6ba8024ef18dafd3
https://doi.org/10.1016/j.yjmcc.2020.05.016
https://doi.org/10.1016/j.yjmcc.2020.05.016